公开(公告)号：US20140128582A1

公开(公告)日：2014-05-08

申请号：US13669691

申请日：2012-11-06

Applicant: Zer-Ran Yu ,  Be-Jen Wang

Inventor： Zer-Ran Yu ,  Be-Jen Wang

IPC: C07J17/00 ,  C08B37/00

CPC classification number: C08B37/0003 ,  C07J17/005 ,  C08B37/00 ,  Y02P20/544

Abstract: The present invention provides a continuous preparation method of ginseng ginsenosides and polysaccharides, whereby the ginseng extract liquor and supercritical solvent are poured continuously into a separation tank at 10-30 MPa and 40-60° C. as well as a preset flow rate; so the ginseng extract liquor can be separated in the separation tank to obtain ginseng ginsenosides and polysaccharides at different positions of the separation tank.

Abstract translation: 本发明提供人参人参皂苷和多糖的连续制备方法，其中人参提取液和超临界溶剂在10-30MPa和40-60℃以及预设流速下连续注入分离罐中; 所以可以在分离罐中分离人参提取液，以在分离罐的不同位置获得人参人参皂苷和多糖。

公开(公告)号：US20120083592A1

公开(公告)日：2012-04-05

申请号：US12894387

申请日：2010-09-30

Applicant: Zer-Ran Yu ,  Be-Jen Wang

Inventor： Zer-Ran Yu ,  Be-Jen Wang

IPC: C07H1/08

CPC classification number: C08B37/0003 ,  B01J3/008 ,  B01J2219/00135 ,  C07J17/00 ,  C08B37/006 ,  Y02P20/544

Abstract: The present invention provides a continuous preparation method of ginseng ginsenosides and polysaccharides, whereby the ginseng extract liquor and supercritical solvent are poured continuously into a separation tank at 10-30 MPa and 40-60° C. as well as a preset flow rate; so the ginseng extract liquor can be separated in the separation tank to obtain ginsenosides and polysaccharides at different positions of the separation tank.

Abstract translation: 本发明提供人参人参皂苷和多糖的连续制备方法，其中人参提取液和超临界溶剂在10-30MPa和40-60℃以及预设流速下连续注入分离罐中; 所以可以在分离槽中分离人参提取液，以在分离罐的不同位置获得人参皂苷和多糖。

公开(公告)号：US08277855B2

公开(公告)日：2012-10-02

申请号：US12776091

申请日：2010-05-07

Applicant: Zer-Ran Yu ,  Be-Jen Wang

Inventor： Zer-Ran Yu ,  Be-Jen Wang

IPC: A23L1/48 ,  C12N1/00

CPC classification number: C11C3/003 ,  C11C1/08 ,  C12P7/6436 ,  Y02P20/544

Abstract: The present invention provides a method of continuously producing edible lipid-based composition, including the steps: preparing alcohol and organic acid in a predetermined ratio and a reaction tank received with immobilized candida cylindracea; continuously providing a supercritical state solvent into the reaction tank and draining the supercritical state solvent out, and mixing and pressurizing the alcohol and the organic acid and sending the alcohol and the organic acid to the reaction tank for a esterfication of the alcohol and the organic acid by the candida cylindracea; getting an edible lipid-based composition and water in the reaction tank; and quickly separating the edible lipid-based composition from the water and the supercritical state solvent.

Abstract translation: 本发明提供一种连续生产食用脂质基组合物的方法，包括以规定比例制备醇和有机酸和以固定的念珠菌圆柱菌收获的反应罐; 向反应槽中连续提供超临界状态溶剂，并排出超临界状态溶剂，并将醇和有机酸混合加压，并将醇和有机酸送入反应罐中，以使醇和有机酸进行酯化反应 由念珠菌圆柱菌 在反应罐中得到可食用的基于脂质的组合物和水; 并迅速将可食用的基于脂质的组合物与水和超临界状态溶剂分离。

公开(公告)号：US20130287927A1

公开(公告)日：2013-10-31

申请号：US13455542

申请日：2012-04-25

Applicant: Zer-Ran YU ,  Be-Jen Wang

Inventor： Zer-Ran YU ,  Be-Jen Wang

IPC: C12H1/06 ,  A23L1/308 ,  C12G1/00

CPC classification number: C12G3/06

Abstract: The present invention provides a preparation method and system for clarified plum wine and plum extract, blanching plum at 95° C. for 5 minutes, and then extracting the blanched plum with extracting solution containing 70-75% alcohol in volume ratio of 1:2 (w/v) at 8˜10° C. in vacuum for 30 minutes before centrifugation, cooling clarification of the plum juice at −8° C. and −20° C. is carried out immediately for 30 minutes respectively, so as to obtain clarified plum wine. Afterwards, the plum wine is concentrated in vacuum to ⅕ of original volume to obtain clarified plum extract; therefore, high quality plum wine and plum extract can be obtained without destroying the plum tissue, and the production efficiency is quite ideal.

Abstract translation: 本发明提供了一种澄清的李子酒和李子提取物的制备方法和系统，在95℃下漂白5分钟，然后用含有70-75％醇的提取溶液以1:2的体积比提取漂白的李子 （w / v）在8〜10℃下真空离心30分钟，分别在-8℃和-20℃下将李子汁冷却澄清30分钟， 获得澄清的李子酒。 之后，将李子酒真空浓缩至原来体积的1/5，得到澄清的李子提取物; 因此，可以在不破坏李子组织的情况下获得高品质的梅花酒和李子提取物，生产效率相当理想。

公开(公告)号：US20130075336A1

公开(公告)日：2013-03-28

申请号：US13241752

申请日：2011-09-23

Applicant: Zer-Ran Yu ,  Be-Jen Wang

Inventor： Zer-Ran Yu ,  Be-Jen Wang

IPC: B01D61/00 ,  B01D35/18

CPC classification number: A61K36/074 ,  A61K2236/00 ,  B01D61/142

Abstract: The present invention provides a method and system for continuous separation and purification of ganoderic acids and polysaccharides, which, via the help of supercritical fluid technology, could feed continuously Ganoderma extract and supercritical solvents at a predefined rate into a separator under operating pressure 10-30 MPa and temperature 40-60° C.; then ganoderic acids, polyphenols and polysaccharides can be separated from Ganoderma extract in the separator; with introduction of membrane purification technology, ganoderic acids, polyphenols and polysaccharides are fed continuously to different purifiers to obtain high-purity ganoderic acids, polyphenols and polysaccharides.

Abstract translation: 本发明提供了一种用于连续分离和纯化甘油酸和多糖的方法和系统，其通过超临界流体技术的帮助，可以将预定速率的灵芝提取物和超临界溶剂以工作压力10-30 MPa和温度40-60℃。 然后可以将甘油酸，多酚和多糖与分离器中的灵芝提取物分离; 通过引入膜纯化技术，将甘油酸，多酚和多糖连续进料到不同的净化器中，得到高纯度的甘油酸，多酚和多糖。

公开(公告)号：US20130289300A1

公开(公告)日：2013-10-31

申请号：US13455356

申请日：2012-04-25

Applicant: Zer-Ran Yu ,  Be-Jen Wang

Inventor： Zer-Ran Yu ,  Be-Jen Wang

IPC: C07C67/58

CPC classification number: C07C67/03 ,  C07C67/58 ,  Y02P20/544 ,  C07C69/145 ,  C07C69/732

Abstract: The present invention provides a method and system for separating linalyl acetate from Lavender essential oil and preparing its derivatives, whereby the supercritical fluid technology is used to feed Lavender essential oil and supercritical solvent into the first separating tank, where linalyl acetate and linalool are separated from Lavender essential oil; then linalyl acetate is conveyed to the second separating tank, where linalyl acetate is separated with wax-containing oily substance to obtain high-concentration linalyl acetate; next linalool and vitamin C solution are conveyed to a reaction tank for esterification synthesis, and the reaction tank is filled with acid resin catalyst to obtain linalool-vitamin C derivative; with this design, it is possible to reduce the nervous tension, and adjust high-concentration linalyl acetate affecting physiological and psychological stress, as well as vitamin C derivative with anti-oxidizing oily fragrance.

Abstract translation: 本发明提供了一种从薰衣草精油中分离乙酸里哪酯和制备其衍生物的方法和系统，由此使用超临界流体技术将薰衣草精油和超临界溶剂进料到第一分离罐中，其中乙酸芳樟醇和芳樟醇分离 薰衣草精油; 然后将乙酸里哪酯输送到第二分离罐，乙酸芳樟酯用含蜡油状物分离，得到高浓度的里哪醇乙酸酯; 将下一个芳樟醇和维生素C溶液输送到反应罐进行酯化合成，反应槽中充满酸性树脂催化剂，得到芳樟醇 - 维生素C衍生物; 通过这种设计，可以减轻神经紧张，并调节高浓度的醋酸里哪酯影响生理和心理压力，以及具有抗氧化油性香料的维生素C衍生物。

公开(公告)号：US20120309947A1

公开(公告)日：2012-12-06

申请号：US13151895

申请日：2011-06-02

Applicant: Zer-Ran YU ,  Be-Jen Wang

Inventor： Zer-Ran YU ,  Be-Jen Wang

IPC: C07J75/00 ,  B01D11/04

CPC classification number: B01D11/0407 ,  B01D11/0492 ,  C07J17/005 ,  Y02P20/544

Abstract: The present invention provides a method and system for continuous separation and purification of ginsenosides, whereby supercritical fluid technology is used to feed Ginseng extract liquor and supercritical solvent continuously into a separation tank at 20-30 Mpa and 40-60° C., such that ginsenosides can be separated from Ginseng extract liquor; then, ginsenosides are continuously fed to a purifying tank for obtaining highly pure ginsenosides; this system comprising: a holding tank, used to accommodate Ginseng extract liquor; a separation tank, connected with the holding tank, fitted with an electric heater, and used to separate ginsenosides from Ginseng extract liquor; a supercritical fluid vessel, connected with the separation tank to provide supercritical fluid; a high-pressure metering pump, connected between the supercritical fluid vessel and separation tank; a reactant metering pump, connected between the holding tank and separation tank; a precooler, connected between the supercritical fluid vessel and high-pressure metering pump; two preheaters, connected separately between the high-pressure metering pump, reactant metering pump and separation tank; a purifying tank, connected with the separation tank, fitted with an electric heater, and used to purify ginsenosides; two temperature controllers, connected separately with the electric heater in the separation tank and purifying tank.

Abstract translation: 本发明提供人参皂苷的连续分离纯化方法和系统，由此使用超临界流体技术将人参提取液和超临界溶剂连续加入到20-30Mpa和40-60℃的分离罐中，使得 人参皂甙可与人参提取液分离; 然后，将人参皂苷连续地加入纯化槽中以获得高纯度人参皂苷; 该系统包括：用于容纳人参提取液的容纳槽; 与储存罐连接的分离罐，装有电加热器，用于将人参皂甙与人参提取液分离; 超临界流体容器，与分离罐连接以提供超临界流体; 连接在超临界流体容器和分离罐之间的高压计量泵; 反应物计量泵，连接在储罐和分离罐之间; 连接在超临界流体容器和高压计量泵之间的预冷器; 两个预热器，分别连接在高压计量泵，反应物计量泵和分离罐之间; 净化罐，与分离罐相连，装有电加热器，用于净化人参皂苷; 两个温度控制器，分别与分离罐和净化罐中的电加热器相连。

公开(公告)号：US20110274784A1

公开(公告)日：2011-11-10

申请号：US12776091

申请日：2010-05-07

Applicant: Zer-Ran YU ,  Be-Jen Wang

Inventor： Zer-Ran YU ,  Be-Jen Wang

IPC: A23L1/48

CPC classification number: C11C3/003 ,  C11C1/08 ,  C12P7/6436 ,  Y02P20/544

Abstract: The present invention provides a method of continuously producing edible lipid-based composition, including the steps: preparing alcohol and organic acid in a predetermined ratio and a reaction tank received with immobilized candida cylindracea; continuously providing a supercritical state solvent into the reaction tank and draining the supercritical state solvent out, and mixing and pressurizing the alcohol and the organic acid and sending the alcohol and the organic acid to the reaction tank for a esterfication of the alcohol and the organic acid by the candida cylindracea; getting an edible lipid-based composition and water in the reaction tank; and quickly separating the edible lipid-based composition from the water and the supercritical state solvent.

Abstract translation: 本发明提供一种连续生产食用脂质基组合物的方法，包括以规定比例制备醇和有机酸和以固定的念珠菌圆柱菌收获的反应罐; 向反应槽中连续提供超临界状态溶剂，并排出超临界状态溶剂，并将醇和有机酸混合加压，并将醇和有机酸送入反应罐中，以使醇和有机酸进行酯化反应 由念珠菌圆柱菌 在反应罐中得到可食用的基于脂质的组合物和水; 并迅速将可食用的基于脂质的组合物与水和超临界状态溶剂分离。

公开(公告)号：US09266920B2

公开(公告)日：2016-02-23

申请号：US14151121

申请日：2014-01-09

Applicant: Zer-Ran Yu ,  Shuen-An Kang

Inventor： Zer-Ran Yu ,  Po-Wen Yu ,  Be-Jen Wang

IPC: C07J9/00

CPC classification number: C07J9/00 ,  Y02P20/544

Abstract: The present invention provides a preparation method of deglycosylated ginsenosides, which uses the supercritical fluid technology to conduct the deglycosylation of ginsenosides extract in supercritical solvent under preset pressure and temperature conditions. Under the same operational conditions, the deglycosylated ginsenosides extract and solvent at supercritical state are input into an adsorption tank at the preset volume flow rate ratio for the adsorption of ginsenosides. Then, the adsorbed ginsenosides are applied with gradient eluent by using the ethanol solution. Finally, the pressure is lowered for the separation and purification of ginsenosides to get the deglycosylated ginsenosides of high concentration.

Abstract translation: 本发明提供了一种去糖基化人参皂甙的制备方法，其使用超临界流体技术在预设的压力和温度条件下在超临界溶剂中进行人参皂苷提取物的去糖基化。 在相同的操作条件下，将去糖基化人参皂甙提取物和超临界状态的溶剂以预设的体积流量比输入吸附罐，用于吸附人参皂甙。 然后，使用乙醇溶液将吸附的人参皂苷施加梯度洗脱液。 最后，降低人参皂苷的分离和纯化的压力，得到高浓度的去糖基化人参皂苷。