公开(公告)号：US20170176320A1

公开(公告)日：2017-06-22

申请号：US15379546

申请日：2016-12-15

Applicant: rap.ID Particle Systems GMBH

Inventor： Karsten GOEDE ,  Lothar HOLZ ,  Markus LANKERS ,  Oliver K. VALET

IPC: G01N21/03 ,  G01N33/483 ,  G01N21/65

CPC classification number: G01N21/03 ,  G01J3/44 ,  G01N21/65 ,  G01N33/483 ,  G01N2021/0385 ,  G01N2021/0389 ,  G01N2201/0846 ,  G01N2201/10

Abstract: The invention relates to a system (1) for confocal Raman-spectroscopic measurements, comprising at least the following components: a sample chamber (10), wherein said sample chamber (10) is configured to house a sample (2) in a closed chamber volume (12) of the sample chamber (10), an excitation light source (3), an objective lens (4), configured to focus excitation light (32) of the excitation light source (3) through a ceiling portion (11) of the sample chamber (10) in a focal volume (31) in the chamber volume (12) and to collect inelastically scattered light (33) stemming from the focal volume (31), a confocal detection arrangement (20), comprising means for a confocal detection (22, 23) of a Raman signal comprised in the inelastically scattered light (33) from the focal volume (31), and a detector (21) that is configured to detect and to record said Raman signal, wherein the distance (5) between the ceiling portion (11) of the sample chamber (10) and the focal volume (31) is greater than one millimetre during operation of the system (1).