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公开(公告)号:US12274499B2
公开(公告)日:2025-04-15
申请号:US17205501
申请日:2021-03-18
Applicant: OPTOS PLC
Inventor: Praveen Ashok , Alan Anderson
Abstract: A multimode optical coherence tomography (OCT) imaging system comprises a light source arranged to emit coherent light in a path to scan a sample. An optical parameter unit is arranged in the path and is operable in at least one selected mode from among a plurality of available operating modes, including at least a first mode, a second mode and a third mode. A detector is arranged to detect reflected light, the reflected light being light reflected in the path as a result of the coherence light scanning the sample. A controller is arranged to control at least one of the light source or the optical parameter unit. The first, second and third modes include a retina mode, anterior segment mode, and biometry mode, respectively. Also provided are a method for operating a multimode OCT imaging system, and a computer-readable storage medium storing a program for performing the method.
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公开(公告)号:US20250082199A1
公开(公告)日:2025-03-13
申请号:US18884958
申请日:2024-09-13
Applicant: Optos plc
Inventor: Miguel Preciado , Paul McCool , Margaret Normand , Ewan Rycroft , Alan Anderson
Abstract: A Fourier-domain OCT apparatus for acquiring optoretinography data, comprising: an optical system which applies an optical stimulus to a retina of an eye; an OCT imaging system which acquires OCT data from the retina; and a controller which: controls the OCT imaging system to acquire OCT data of a plurality of portions of the retina such that, for each portion, at least some of the OCT data from the portion is acquired after a respective optical stimulus has been applied to the portion; generates, based on the OCT data, respective ORG data for each portion which indicates the response of the portion to the optical stimulus; and stores respective ORG data generated for each portion in association with a respective position in a visual field of the eye that is optically conjugate with a position of the portion on the retina.
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3.
公开(公告)号:US20240415385A1
公开(公告)日:2024-12-19
申请号:US18743202
申请日:2024-06-14
Applicant: Optos plc
Inventor: David Clifton
Abstract: Aspects of the present invention relate to a method of suppressing a banding artefact in an ophthalmic image of a patient's eye. The method comprises: partitioning the ophthalmic image into a plurality of segments that partially overlap each other, applying an image correction algorithm, which computes a discrete cosine transform of each segment of the plurality of segments to suppress the banding artefact in the plurality of segments removing at least part of the one or more overlapping regions from each segment to remove an artefact introduced by the image correction algorithm to generate a respective corrected segment; and combining the corrected segments to generate a corrected ophthalmic image that comprises less of the banding artefact than the ophthalmic image.
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公开(公告)号:US12137976B2
公开(公告)日:2024-11-12
申请号:US17200800
申请日:2021-03-13
Applicant: OPTOS PLC
Inventor: Praveen Ashok , David Evans
IPC: A61B3/10 , A61B3/00 , G01B9/02091
Abstract: An ophthalmic optical coherence tomography instrument, method, and computer-readable medium. The instrument includes a scanner defining an apparent point source for scanning sample light across a subject position and an objective having a posterior imaging configuration to project the apparent point source onto a pivot point between the objective and the subject position. The objective is settable between the posterior imaging configuration for scanning the sample light across a retina of an eye at the subject position and an anterior imaging configuration for scanning the sample light across a pivot plane. An axial region from which an interferogram is detectable extends across the pivot plane while the objective is in the anterior imaging configuration. A pupil alignment method uses the anterior imaging modality to obtain a structure position of a structure of an eye's anterior segment and then an offset between the structure position and a reference position.
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公开(公告)号:US12059210B2
公开(公告)日:2024-08-13
申请号:US17035152
申请日:2020-09-28
Applicant: NIKON CORPORATION , OPTOS PLC
Inventor: Gonzalo Muyo , Alistair Gorman , David M. Williamson , Makoto Fujimoto , Yasufumi Nishi , Azuna Nonaka , Katsuya Watanabe , Miwako Yoshida , Kyoya Tokunaga , Masahiro Mizuta
CPC classification number: A61B3/14 , A61B3/0008 , A61B3/0041
Abstract: The ophthalmic optical system is configured to apply an angular scanning light ray to an eye. M=|ωout/ωin| is defined, where ωin represents an angle between an incident light ray to the ophthalmic optical system and an optical axis of the ophthalmic optical system, and ωout represents an angle between an exiting light ray exiting from the ophthalmic optical system toward the eye and the optical axis. The ophthalmic optical system satisfies a conditional expression Mpar
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公开(公告)号:US12048481B2
公开(公告)日:2024-07-30
申请号:US17207077
申请日:2021-03-19
Applicant: OPTOS PLC
CPC classification number: A61B3/0025 , A61B3/1005 , A61B3/102 , G16H30/40
Abstract: A technique for generating a mapping relating values of a scan parameter of an ocular imaging apparatus that are indicative of scan locations in an eye at which the apparatus acquires digital images of imaged regions of the eye, to respective values of a conversion factor for calculating a distance between designated ocular features in the imaged regions, by: simulating light ray propagation to relate each value of the scan parameter in a sequence of scan parameter values to a corresponding location in a model eye; calculating, for each scan parameter value, a distance between the corresponding location in the model eye and a location in the model eye corresponding to an adjacent value in the sequence; and using the calculated distances to generate a respective value of the conversion factor for each scan parameter value.
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公开(公告)号:US20240188822A1
公开(公告)日:2024-06-13
申请号:US18527639
申请日:2023-12-04
Applicant: Optos plc
Inventor: Brian Laffoley , Alan Williams
CPC classification number: A61B3/14 , A61B3/0033
Abstract: There is provided a control system for controlling two or more illuminates of a multi-modality ophthalmic imaging system that are arranged to generate light for imaging an eye, the control system comprising: a processor which selects, from the illuminates and based on a selected imaging modality of the ophthalmic imaging system, one or more illuminates that are to be used to image the eye, and to generate an input signal identifying the selected one or more illuminates. The control system further comprises a logic block, which receives the input signal and comprises logic that determines a respective operating power for each illuminate of the selected one or more illuminates, based on the received input signal. The logic block also generates a respective control signal for each illuminate of the selected one or more illuminates, each control signal indicating the respective operating power determined for the respective illuminate.
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公开(公告)号:US20230186683A1
公开(公告)日:2023-06-15
申请号:US17924993
申请日:2020-05-14
Applicant: OPTOS PLC
Inventor: Peter Robert Wakeford , Enrico Pellegrini
IPC: G06V40/18 , G06V10/764
CPC classification number: G06V40/197 , G06V10/764 , G06V2201/07
Abstract: An apparatus for generating an alert indicating an unreliability in a location of a landmark feature in a retinal image predicted by a machine learning algorithm, comprising: a receiver module which receives the predicted location; a probability indication determining module which uses the predicted location and a mixture model, which comprises a probability distribution of a landmark feature location and is based on determined locations of the landmark feature in retinal images having a plurality of retinal image classes, to determine, for each class, a respective probability indication indicating a probability that the retinal image belongs to the class; an outlier detector module which uses the probability indications to determine whether the retinal image is an outlier belonging to none of the classes; and an alert generator module which generates, when the retinal image belongs to none of the classes, an alert indicating unreliability of the predicted location.
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公开(公告)号:US11676255B2
公开(公告)日:2023-06-13
申请号:US17401957
申请日:2021-08-13
Applicant: Optos Plc
Inventor: Muzammil A. Arain , Jeffery Benshetler , Eugene Russiyanov , Tushar M. Ranchod
IPC: G06T5/50 , G06V40/18 , G06T7/73 , G06T3/40 , G06T11/00 , G06T7/11 , G06T7/64 , G06T7/00 , H04N23/90 , H04N23/698
CPC classification number: G06T5/50 , G06T3/4007 , G06T7/0014 , G06T7/11 , G06T7/64 , G06T7/73 , G06T11/00 , G06V40/193 , G06V40/197 , H04N23/698 , H04N23/90 , G06T2207/20021 , G06T2207/20068 , G06T2207/20081 , G06T2207/20221 , G06T2207/30041 , G06T2207/30204
Abstract: Generating a correction algorithm includes obtaining a model of an eye, the model including a front portion with optics to mimic a cornea and a lens of a human eye, and a rear portion having a generally hemispherical-shaped body to mimic a retina of the human eye. The rear portion includes physical reference lines on an inside surface of the generally hemispherical-shaped body. Images of the model are captured using an image capturing device aimed at the model. Vertices of the physical reference lines are identified according to a given projection technique for displaying generally hemispherical-shaped body in a two-dimensional image in the captured images. Idealized placement of the vertices of the physical reference lines is obtained according to the given projection technique. The result is a correction algorithm used to adjust any pixel of an image of an actual eye in the x-axis and in the y-axis.
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10.
公开(公告)号:US11568540B2
公开(公告)日:2023-01-31
申请号:US16594934
申请日:2019-10-07
Applicant: OPTOS PLC
Inventor: David Clifton
Abstract: A method, system, and computer-readable medium, for detecting whether an eye blink or non-blink is captured in the image. The method includes filtering, from the image, one or more objects that are predicted to be unsuitable for determining whether an eye blink or no-blink is captured in the image, to provide a filtered image. The method also includes correlating the filtered image with a reference image, and determining, based on the correlating, whether the eye blink or non-blink is captured in the image. The eye blink is a full eye blink or a partial eye blink, and the images may be sequentially captured IR SLO images, in one example embodiment herein. Images determined to include an eye blink can be omitted from inclusion in a final (e.g., OCT) image.
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