Pharmaceutical tablet press control mechanism
    2.
    发明授权
    Pharmaceutical tablet press control mechanism 失效
    制药压片机控制机构

    公开(公告)号:US4817006A

    公开(公告)日:1989-03-28

    申请号:US414158

    申请日:1988-01-07

    Applicant: David A. Lewis

    Inventor: David A. Lewis

    CPC classification number: B30B15/32 B30B11/005

    Abstract: Control and monitoring instrumentation for a high speed double rotary tablet press mechanism is disclosed. Each tablet press side has strain gauges producing signals indicative of table compression. The strain gauges generate control signals received by a peak detector, which holds the maximum strain signal. The peak signals are converted to digital form and provided to a microprocessor that first controls operation of the reject gate and regulates tablet consistency by controlling powder fill into the dies, and second, passes information to RAM. The RAM is shared by a master CPU, clocked 180.degree. out of phase with the microprocessor. The master CPU produces either a CRT or printed output of both raw and statistically abstracted tablet press data.

    Abstract translation: 公开了一种用于高速双旋转压片机构的控制和监测仪器。 每个压片机侧都有应变仪产生表示压缩的信号。 应变计产生由峰值检测器接收的控制信号,峰值检测器保持最大应变信号。 峰值信号被转换为数字形式并提供给微处理器,其首先控制拒绝门的操作并通过控制粉末填充到管芯中来调节片剂一致性,其次将信息传递到RAM。 RAM由主CPU共享,与微处理器同步180度。 主CPU产生原始和统计抽象的平板电脑数据的CRT或打印输出。

    Method and apparatus for coating particulate granules
    3.
    发明授权
    Method and apparatus for coating particulate granules 失效
    用于涂覆颗粒的方法和设备

    公开(公告)号:US4639383A

    公开(公告)日:1987-01-27

    申请号:US854735

    申请日:1986-04-21

    Inventor: Thomas J. Casey

    CPC classification number: B05D1/02 A23G3/26 A61J3/005 B01F5/205 B01J2/006

    Abstract: A method and apparatus for coating particulate granules is disclosed. The method is practiced by providing a fluidized charge of granules suspended in a flow of a drying gas within a rotating perforated coating pan. A portion of the fluidized granules is drawn along the pan's surface to a position above the fluidized charge of granules and allowed to cascade back into the fluidized charge. Flow of the drying gas is concentrated in the vicinity of the granules movement, and a coating material is dispensed onto the moving granules. The apparatus disclosed comprises a rotating perforated pan having gas inlet and exhaust plenums in contact with the rotating pan's exterior. The inlet plenum introduces a stream of drying gas to fluidize and suspend the agitated granules; the outlet plenum exhausts the drying gas and thereby draws granules along the pan's inner surface to the outlet plenum's position. A means for rotating the pan is provided, as is a pump or vacuum source for drawing granules to the exhaust plenum's location. Means for dispensing coating material within the pan are provided. In an alternative embodiment, a purge system is disclosed that dislodges granules that have become attached to the pan's perforated surface.

    Abstract translation: 公开了一种用于涂覆颗粒的方法和设备。 该方法通过提供悬浮在旋转穿孔涂布盘内的干燥气体流中的颗粒的流化装料来实施。 流化颗粒的一部分沿着盘的表面被吸引到颗粒流化装置上方的位置,并使其逐级回到流化的装料中。 干燥气体的流动集中在颗粒运动附近,并且将涂料分配到移动的颗粒上。 所公开的装置包括旋转的多孔板,其具有与旋转盘的外部接触的气体入口和排气增压室。 入口增压室引入干燥气流,使搅拌颗粒流化并悬浮; 出口增压室排出干燥气体,从而将颗粒沿着锅的内表面吸收到出口压力室的位置。 提供用于旋转锅的装置,以及用于将颗粒吸入排气室的位置的泵或真空源。 提供了在锅内分配涂料的方法。 在替代实施例中,公开了一种清除系统,其清除已经附着到盘的穿孔表面上的颗粒。

    Method for monitoring and controlling the weights of each layer of a
multilayer tablet
    4.
    发明授权
    Method for monitoring and controlling the weights of each layer of a multilayer tablet 失效
    用于监测和控制多层片剂每层重量的方法

    公开(公告)号:US5322655A

    公开(公告)日:1994-06-21

    申请号:US20217

    申请日:1993-02-19

    Applicant: Glen C. Ebey

    Inventor: Glen C. Ebey

    Abstract: A method for controlling and monitoring instrumentation for a multilayer tablet press mechanism is disclosed. The compression for each layer, other than the first, takes the measured variable or error from the previous layer control loop and applies a transformation to that variable or error. The resulting transformation is then used as a compensation to the subsequent layer control loop in the form of a modified set point, modified measure variable, modified error, or modified control output. Additionally, the variable or error resulting from the previous control loop is fed back into the controller for the previous control loop so that any adjustments necessary in the previous layer loop may be completed. The variable or error is also used to determine whether to accept or reject the tablet.

    Abstract translation: 公开了一种用于多层压片机构的控制和监测仪器的方法。 除了第一个层之外,每个层的压缩取自前一层控制循环的测量变量或误差,并对该变量或错误应用变换。 然后将所得到的变换作为对修改的设定点,修改的测量变量,修改的错误或修改的控制输出的形式的后续层控制循环的补偿。 另外,由先前的控制回路产生的变量或误差被反馈到用于先前控制回路的控制器中,以便可以完成先前的层循环中所需的任何调整。 变量或错误也用于确定是否接受或拒绝平板电脑。

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