The invention relates to a speech enhancement method based on a multi-head self-attention mechanism and relates to the technical field of speech enhancement. According to the method, for the problem that noises cannot be clearly suppressed in an attention computing process through adoption of the speech enhancement method based on an attention mechanism, on the basis of research and utilization ofmasking effect existing in an auditory perception process of people, the invention provides the speech enhancement method based on the multi-head self-attention mechanism. According to the method, the part of suppressing noises in the attention mechanism computing process is realized, and speech enhancement performance is improved.