Invention Grant
- Patent Title: Systems and methods for screening a sample based on multiple reaction monitoring mass spectrometry
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Application No.: US15649763Application Date: 2017-07-14
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Publication No.: US10168312B2Publication Date: 2019-01-01
- Inventor: Robert Graham Cooks , Christina Ramires Ferreira , Tiago Sobreira
- Applicant: Purdue Research Foundation
- Applicant Address: US IN West Lafayette
- Assignee: PURDUE RESEARCH FOUNDATION
- Current Assignee: PURDUE RESEARCH FOUNDATION
- Current Assignee Address: US IN West Lafayette
- Agency: Purdue Research Foundation
- Main IPC: H01J49/42
- IPC: H01J49/42 ; G01N33/48 ; G01N33/487 ; G06F17/30 ; H01J49/00 ; H01J49/16 ; H04L1/00 ; G06F19/00
Abstract:
The invention generally relates to systems methods for screening a sample based on multiple reaction monitoring mass spectrometry. In certain embodiments, the invention provides methods for screening a sample that involve ionizing a sample. Mass spectrometry is then used in order to monitor specific transitions connecting one or more ion pairs within the sample in order to generate a multidimensional chemical profile of the sample. Then, the multidimensional chemical profile of the sample is compared to a database of reference multidimensional chemical profiles, thereby screening the sample. Each reference multidimensional chemical profile is produced from a training set of data.
Public/Granted literature
- US20180024108A1 SYSTEMS AND METHODS FOR SCREENING A SAMPLE BASED ON MULTIPLE REACTION MONITORING MASS SPECTROMETRY Public/Granted day:2018-01-25
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