An overhead valve actuation mechanism for an engine includes a camshaft that is rotatably supported by the cylinder head and includes one or a plurality of valve cams. The camshaft operates opening and closing of an intake valve and an exhaust valve via the valve cam. The only one camshaft is disposed within the one cylinder head. The camshaft has an axis center biased to a side of the exhaust valve with respect to a cylinder axis line as viewed from an axial direction of the camshaft.