- Patent Title: Small molecule N-(alpha-peroxy) indole compounds and methods of use
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Application No.: US16099853Application Date: 2017-05-10
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Publication No.: US10689341B2Publication Date: 2020-06-23
- Inventor: Xinbo Wang , Zhiping Lai , Yupeng Pan , Kuowei Huang , Zhigang Wang
- Applicant: King Abdullah University of Science and Technology
- Applicant Address: SA Thuwal
- Assignee: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Current Assignee: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: SA Thuwal
- Agency: Billion & Armitage
- Agent Lisbeth C. Robinson
- International Application: PCT/IB2017/052742 WO 20170510
- International Announcement: WO2017/195136 WO 20171116
- Main IPC: C07D209/08
- IPC: C07D209/08 ; C07D209/16 ; C07D209/24 ; C07D209/48 ; A61K31/404 ; A61K31/4045 ; A61K45/06 ; C07D209/14 ; C07D209/26 ; C07D403/06

Abstract:
The invention relates to novel N-(α-peroxy)indole compounds of Formula I and methods for use. (I) The N-(α-peroxy)indole compounds described herein are useful for treating or preventing parastic infections, bacterial infections, and cancer in subjects. The methods include administering an N-(α-peroxy)indole compound as described herein to a subject. Also described herein are methods for synthesizing N-(α-peroxy)indole compounds.
Public/Granted literature
- US20190112267A1 SMALL MOLECULE N-(ALPHA-PEROXY) INDOLE COMPOUNDS AND METHODS OF USE Public/Granted day:2019-04-18
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