Invention Grant
- Patent Title: Methods for enhancing mucosal innate immune responses to and/or detection of pathogens using human milk oligosaccharides
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Application No.: US15302793Application Date: 2015-04-03
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Publication No.: US10792294B2Publication Date: 2020-10-06
- Inventor: Rachael Buck , Geralyn Duska-McEwen , Steven Davis
- Applicant: ABBOTT LABORATORIES
- Applicant Address: US IL Abbott Park
- Assignee: ABBOTT LABORATORIES
- Current Assignee: ABBOTT LABORATORIES
- Current Assignee Address: US IL Abbott Park
- Agency: Calfee Halter & Griswold LLP
- International Application: PCT/US2015/024205 WO 20150403
- International Announcement: WO2015/157098 WO 20151015
- Main IPC: A61K31/7016
- IPC: A61K31/7016 ; A61K31/702 ; A23L33/00 ; A23L2/52
Abstract:
A method for enhancing an individual's mucosal innate immune response to pathogens is disclosed. The method includes a step of administering a nutritional composition to the individual. The nutritional composition includes about 0.05 to about 0.5 mg/mL 2′-fucosyllactose (2′-FL), about 0.05 to about 0.5 mg/mL lacto-N-neotetraose (LNnT), or a combination of both. Also disclosed is a method for enhancing an individual's mucosal innate immune detection of pathogens. The method includes a step of administering a nutritional composition to the individual. The nutritional composition includes a neutral human milk oligosaccharide.
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