公开(公告)号：US09433586B2

公开(公告)日：2016-09-06

申请号：US14515203

申请日：2014-10-15

Applicant: ABBOTT LABORATORIES

Inventor： Chron-Si Lai ,  Steven Davis ,  Keith Garleb ,  John Lasekan

IPC: A61K31/19 ,  A61K31/20 ,  A23D7/00 ,  A61K31/05 ,  A61K9/00 ,  A23K1/16 ,  A23K1/18 ,  A23L1/29 ,  A23L1/30

CPC classification number: A61K31/05 ,  A23K20/158 ,  A23K50/30 ,  A23L33/12 ,  A23L33/30 ,  A23L33/40 ,  A23V2002/00 ,  A61K9/00 ,  A61K31/20

Abstract: Disclosed are nutritional formulations including predigested fats that can be administered to preterm infants, infants, toddlers, and children for improving tolerance, digestion, and absorption of nutrients and for reducing the incidence of necrotizing enterocolitis, colic, and short bowel syndrome. The predigested fats include fatty acid-containing monoglycerides and/or a fatty acid component.

Abstract translation: 公开了营养配方，其包括可以对早产儿，婴儿，幼儿和儿童施用的预消化脂肪，用于改善营养物质的耐受性，消化和吸收以及降低坏死性小肠结肠炎，绞痛和短肠综合征的发生率。 预先消化的脂肪包括含脂肪酸的单甘油酯和/或脂肪酸组分。

公开(公告)号：US20160021921A1

公开(公告)日：2016-01-28

申请号：US14777187

申请日：2014-03-14

Applicant: ABBOTT LABORATORIES

Inventor： Steven Davis ,  Barbara Marriage ,  Christine Gallardo ,  Marti Bergana ,  Bridget Barrett-Reis

IPC: A23L1/305 ,  A23C9/20 ,  A23L1/29

CPC classification number: A23C9/206 ,  A23L33/175 ,  A23L33/40 ,  A23V2002/00

Abstract: Preterm infant nutritional compositions comprising beta-hydroxy-beta-methylbutyric acid for supporting growth, accretion of lean body mass, and a healthy body composition in preterm infants are provided. The preterm infant nutritional compositions may be liquid formulas, fortifiers, and supplements. Methods for supporting growth, accretion of lean body mass, and a healthy body composition in a preterm infant are also provided. The methods include administering a preterm infant nutritional composition comprising beta-hydroxy-beta-methylbutyric acid to the preterm infant.

Abstract translation: 提供了包含用于支持生长的β-羟基-β-甲基丁酸的早产儿营养组合物，瘦体重的增加以及早产儿的健康的身体组成。 早产儿营养组合物可以是液体配方，强化剂和补充剂。 还提供了用于支持早产儿的生长，瘦体重增加和健康的身体组成的方法。 所述方法包括向早产婴儿施用包含β-羟基-β-甲基丁酸的早产儿营养组合物。

公开(公告)号：US20160029683A1

公开(公告)日：2016-02-04

申请号：US14777206

申请日：2014-03-14

Applicant: ABBOTT LABORATORIES

Inventor： Steven Davis ,  Barbara Marriage ,  Christine Gallardo ,  Marti Bergana

IPC: A23L1/305 ,  A23L1/29

CPC classification number: A23L33/175 ,  A23L33/40 ,  A23V2002/00

Abstract: Low calorie nutritional compositions comprising beta-hydroxy-beta-methylbutyric acid which may support accretion of lean body mass and development of a healthy body composition in term infants are provided. The low calorie nutritional compositions may be liquid or powder infant formulas.

Abstract translation: 提供了包含可以支持瘦体重增加的β-羟基-β-甲基丁酸的低热量营养组合物以及在婴儿中发展健康的身体组合物。 低热量营养组合物可以是液体或粉末婴儿配方食品。

公开(公告)号：US10792294B2

公开(公告)日：2020-10-06

申请号：US15302793

申请日：2015-04-03

Applicant: ABBOTT LABORATORIES

Inventor： Rachael Buck ,  Geralyn Duska-McEwen ,  Steven Davis

IPC: A61K31/7016 ,  A61K31/702 ,  A23L33/00 ,  A23L2/52

Abstract: A method for enhancing an individual's mucosal innate immune response to pathogens is disclosed. The method includes a step of administering a nutritional composition to the individual. The nutritional composition includes about 0.05 to about 0.5 mg/mL 2′-fucosyllactose (2′-FL), about 0.05 to about 0.5 mg/mL lacto-N-neotetraose (LNnT), or a combination of both. Also disclosed is a method for enhancing an individual's mucosal innate immune detection of pathogens. The method includes a step of administering a nutritional composition to the individual. The nutritional composition includes a neutral human milk oligosaccharide.

公开(公告)号：US10568896B2

公开(公告)日：2020-02-25

申请号：US15037743

申请日：2014-11-18

Applicant: Abbott Laboratories

Inventor： Rachael Buck ,  Steven Davis ,  Paul Forsythe

IPC: A61K31/702 ,  A23L33/125 ,  A23L5/00 ,  A61K45/06 ,  A23L29/30 ,  A61K31/7016 ,  A61K31/4545 ,  A61K31/495 ,  A61K31/445 ,  A23L33/10 ,  A23L33/00 ,  A23L33/21 ,  A23L33/115 ,  A23L29/00 ,  A23L21/00

Abstract: A method for preventing or mitigating an acute allergic response in a subject is disclosed. The method includes a step of administering a nutritional composition to the subject. The nutritional composition includes at least one of an acidic or a neutral HMO, but does not include an N-acetyl-lactosamine.

公开(公告)号：US11135233B2

公开(公告)日：2021-10-05

申请号：US16730139

申请日：2019-12-30

Applicant: Abbott Laboratories

Inventor： Rachael Buck ,  Steven Davis ,  Paul Forsythe

IPC: A61K31/702 ,  A61K31/7016 ,  A23L33/125 ,  A23L5/00 ,  A61K45/06 ,  A23L29/30 ,  A61K31/4545 ,  A61K31/495 ,  A61K31/445 ,  A23L33/10 ,  A23L33/00 ,  A23L33/21 ,  A23L33/115 ,  A23L29/00 ,  A23L21/00

Abstract: A method for preventing or mitigating an acute allergic response in a subject is disclosed. The method includes a step of administering a nutritional composition to the subject. The nutritional composition includes at least one of an acidic or a neutral HMO, but does not include an N-acetyl-lactosamine.