Invention Grant
- Patent Title: Fusion proteins and methods for stimulating plant growth, protecting plants, and immobilizing bacillus spores on plants
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Application No.: US17025483Application Date: 2020-09-18
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Publication No.: US11882829B2Publication Date: 2024-01-30
- Inventor: Brian Thompson , Katie Thompson
- Applicant: Spogen Biotech Inc.
- Applicant Address: US MO St. Louis
- Assignee: Spogen Biotech Inc.
- Current Assignee: Spogen Biotech Inc.
- Current Assignee Address: US MO St. Louis
- Agency: Dentons US LLP
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A01N37/46 ; A01N63/50 ; A01N63/22 ; A01N63/10 ; A61K38/16 ; C07K14/32 ; C12N9/02 ; C12N9/16 ; C12N9/24 ; A01N37/48 ; C12N9/20 ; C12N9/42 ; C12N9/48 ; A61K39/07

Abstract:
The present invention is generally directed to fusion proteins containing a targeting sequence that targets the fusion protein to the exosporium of a Bacillus cereus family member. The invention also relates to recombinant Bacillus cereus family members expressing such fusion proteins and formulations containing the recombinant Bacillus cereus family members expressing the fusion proteins. Methods for stimulating plant growth, for protecting plants from pathogens, and for enhancing stress resistance in a plant by applying the recombinant Bacillus cereus family members or the formulations to plants or a plant growth medium are also described. The invention also relates to methods for immobilizing spores of a recombinant Bacillus cereus family member expressing a fusion protein on plants.
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