Invention Grant
- Patent Title: Chimeric influenza vaccines
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Application No.: US17998208Application Date: 2021-05-07
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Publication No.: US11918641B2Publication Date: 2024-03-05
- Inventor: Chi-Huey Wong , Hsin-Yu Liao , Shih-Chi Wang , Yi-An Ko , Kuo-I Lin , Che Ma , Ting-Jen Cheng
- Applicant: ACADEMIA SINICA
- Applicant Address: TW Taipei
- Assignee: ACADEMIA SINICA
- Current Assignee: ACADEMIA SINICA
- Current Assignee Address: TW Taipei
- Agency: Prosyla Group, PC
- International Application: PCT/US2021/031406 2021.05.07
- International Announcement: WO2021/226533A 2021.11.11
- Date entered country: 2022-11-08
- Main IPC: A61K39/145
- IPC: A61K39/145 ; A61K35/76 ; A61K39/00 ; A61K39/12 ; A61P31/16 ; C07K14/005 ; C07K14/11

Abstract:
The present disclosure relates to a chimeric influenza virus hemagglutinin (HA) polypeptide, comprising one or more stem domain sequence, each having at least 60% homology with a stem domain consensus sequence of H1 subtype HA (H1 HA) and/or H5 subtype HA (H5 HA), fused with one or more globular head domain sequence, each having at least 60% homology with a globular head domain consensus sequence of H1 subtype HA (H1 HA) or H5 subtype HA (H5 HA).
Public/Granted literature
- US20230302114A1 CHIMERIC INFLUENZA VACCINES Public/Granted day:2023-09-28
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