Invention Application
- Patent Title: SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORS
- Patent Title (中): 氨基酸连接基团的合成和组合与用于靶向成像肿瘤的化合物
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Application No.: US14715799Application Date: 2015-05-19
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Publication No.: US20160011199A1Publication Date: 2016-01-14
- Inventor: Sumith A. Kularatne , Sakkarapalayam M. Mahalingam , Philip S. Low
- Applicant: Purdue Research Foundation
- Main IPC: G01N33/574
- IPC: G01N33/574 ; G01N33/58 ; A61K49/00 ; C07D475/04
Abstract:
The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds.
Public/Granted literature
Information query
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