Invention Publication
- Patent Title: POLYPHENOL INFUSED PROBIOTICS AND METHODS FOR IMPROVED GUT SURVIVABILITY, PERSISTENCE AND COLONIZATION
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Application No.: US18542860Application Date: 2023-12-18
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Publication No.: US20240150705A1Publication Date: 2024-05-09
- Inventor: Nitin Nitin , Rewa Rai , Marluci Palazzolli da Silva Padilha
- Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Applicant Address: US CA Oakland
- Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee Address: US CA Oakland
- Main IPC: C12N1/04
- IPC: C12N1/04 ; A61K35/745 ; A61K35/747 ; A61K36/61 ; A61K36/77 ; A61K36/87 ; C12N1/20 ; C12R1/23 ; C12R1/245 ; C12R1/25
Abstract:
Vacuum infusion of plant extracts in live probiotic cells significantly enhances the viability of probiotics during in vitro gastrointestinal digestion with the retention of their metabolic and antagonistic activities. In-vivo results validate the significantly enhanced persistence and mucoadhesion of probiotic cells with infused plant extracts.
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