Invention Grant
US08715640B2 Packaging cells for producing retrovirus pseudotyped with an E2 alphavirus glycoprotein
有权
用于产生用E2甲病毒糖蛋白假型包装的逆转录病毒的包装细胞
- Patent Title: Packaging cells for producing retrovirus pseudotyped with an E2 alphavirus glycoprotein
- Patent Title (中): 用于产生用E2甲病毒糖蛋白假型包装的逆转录病毒的包装细胞
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Application No.: US12688689Application Date: 2010-01-15
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Publication No.: US08715640B2Publication Date: 2014-05-06
- Inventor: Pin Wang , Lilli Yang , David Baltimore
- Applicant: Pin Wang , Lilli Yang , David Baltimore
- Applicant Address: US CA Pasadena
- Assignee: California Institute of Technology
- Current Assignee: California Institute of Technology
- Current Assignee Address: US CA Pasadena
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A01N65/00 ; C12N5/00
Abstract:
Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers.
Public/Granted literature
- US20100120122A1 TARGETED GENE DELIVERY FOR DENDRITIC CELL VACCINATION Public/Granted day:2010-05-13
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