Invention Grant
US09117642B2 Interfacing capillary electrophoresis to a mass spectrometer via an impactor spray ionization source 有权
通过冲击器喷雾电离源将毛细管电泳与质谱仪连接

  • Patent Title: Interfacing capillary electrophoresis to a mass spectrometer via an impactor spray ionization source
  • Patent Title (中): 通过冲击器喷雾电离源将毛细管电泳与质谱仪连接
  • Application No.: US14367647
    Application Date: 2012-12-21
  • Publication No.: US09117642B2
    Publication Date: 2015-08-25
  • Inventor: Stevan Bajic
  • Applicant: Micromass UK Limited
  • Applicant Address: GB Wilmslow
  • Assignee: Micromass UK Limited
  • Current Assignee: Micromass UK Limited
  • Current Assignee Address: GB Wilmslow
  • Agency: Diederiks & Whitelaw, PLC
  • Priority: GB1122218.9 20111223; GB1202892.4 20120221; GB1219217.5 20121025
  • International Application: PCT/GB2012/053258 WO 20121221
  • International Announcement: WO2013/093517 WO 20130627
  • Main IPC: H01J49/16
  • IPC: H01J49/16 H01J49/04 H01J49/00 H01J49/10
Interfacing capillary electrophoresis to a mass spectrometer via an impactor spray ionization source
Abstract:
A mass spectrometer is disclosed comprising a separation device arranged and adapted to emit an eluent over a period of time. The separation device preferably comprises a Capillary Electrophoresis (“CE”) separation device. The mass spectrometer further comprises a nebulizer and a target. Eluent emitted by the separation device is nebulized, in use, by the nebulizer wherein a stream of analyte droplets are directed to impact upon the target so as to ionize the analyte to form a plurality of analyte ions.
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