Invention Grant
- Patent Title: Apparatus and methods for ion mobility spectrometry
- Patent Title (中): 用于离子迁移谱的装置和方法
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Application No.: US14379235Application Date: 2013-02-14
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Publication No.: US09207206B2Publication Date: 2015-12-08
- Inventor: Alexander Makarov
- Applicant: Thermo Fisher Scientific (Bremen) GmbH
- Applicant Address: DE Bremen
- Assignee: Thermo Fisher Scientific (Bremen) GmbH
- Current Assignee: Thermo Fisher Scientific (Bremen) GmbH
- Current Assignee Address: DE Bremen
- Agent David A. Schell
- Priority: GB1202895.7 20120221
- International Application: PCT/EP2013/052994 WO 20130214
- International Announcement: WO2013/124207 WO 20130829
- Main IPC: H01J49/24
- IPC: H01J49/24 ; G01N27/62 ; H01J49/00 ; H01J49/06

Abstract:
A method of ion mobility spectrometry comprising: (i) introducing a packet of ions into a drift space; (ii) passing the ions through the drift space wherein the ions separate according to their ion mobility; and (iii) reflecting or deflecting the ions that have passed through the drift space back into the drift space wherein the ions can further separate according to their ion mobility. The reflecting or deflecting takes place in a region at lower pressure than the drift space. The drift space may be re-used multiple times to extend the separation path length. The regions of low pressure preferably allow inertial ion motion wherein the mean free path between ion collisions with gas is significantly longer than in the stages of ion mobility separation. The low pressure reflecting or deflecting region enables a time of flight focusing of ions to be provided without ion mobility separation occurring therein.
Public/Granted literature
- US20150008318A1 Apparatus and Methods for Ion Mobility Spectrometry Public/Granted day:2015-01-08
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