Invention Grant
US09233175B2 Methods of imaging inflammatory diseases by ligands conjugated to fluorescent compounds
有权
通过与荧光化合物缀合的配体成像炎症疾病的方法
- Patent Title: Methods of imaging inflammatory diseases by ligands conjugated to fluorescent compounds
- Patent Title (中): 通过与荧光化合物缀合的配体成像炎症疾病的方法
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Application No.: US14135099Application Date: 2013-12-19
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Publication No.: US09233175B2Publication Date: 2016-01-12
- Inventor: Philip S. Low , Sumith A. Kularatne , Lindsay E. Kelderhouse , Sakkarapalayam M. Mahalingam
- Applicant: Purdue Research Foundation
- Applicant Address: US IN West Lafayette
- Assignee: Purdue Research Foundation
- Current Assignee: Purdue Research Foundation
- Current Assignee Address: US IN West Lafayette
- Agency: McAndrews, Held & Malloy, Ltd.
- Main IPC: A61K49/00
- IPC: A61K49/00 ; G01N33/569 ; G01N33/566 ; G01N33/50
Abstract:
The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods of imaging of inflammatory diseases using the compounds.
Public/Granted literature
- US20140271484A1 Methods of Imaging Inflammatory Diseases by Ligands Conjugated to Fluorescent Compounds Public/Granted day:2014-09-18
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