Invention Patent
- Patent Title: Adamantyl-acetamide derivatives as inhibitor of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
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Application No.: ZA200609946Application Date: 2006-11-28
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Publication No.: ZA200609946BPublication Date: 2008-06-25
- Inventor: LINK JAMES T , ROHDE JEFFREY J , PATEL JYOTI R , PLIUSHCHEV MARINA A , DARIUSZ WODKA , QI SHUAI
- Applicant: ABBOTT LAB
- Assignee: ABBOTT LAB
- Current Assignee: ABBOTT LAB
- Priority: US83445904 2004-04-29
- Main IPC: A61K
- IPC: A61K20090101 ; C07D20090101 ; C07D205/04 ; C07D211/06 ; C07D211/46 ; C07D213/74 ; C07D295/15
Abstract:
The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, and other diseases and conditions that are mediated by excessive glucocorticoid action.
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