Abstract:
본 발명은 9Z, 11E 공액 리놀레인산을 유효성분으로 함유함을 특징으로 하는 갭 결합을 통한 세포 간 정보 전달 장애 매개 질환의 예방용 조성물에 관한 것으로, 손상된 "갭결합을 통한 세포간 정보전달"을 회복시키고, 항상성을 유지시킴으로써, 갭 결합과 관련된 질환을 예방 및 치료하는 효과가 있다. 9Z, 11E 공액 리놀레인산, 갭 결합
Abstract:
A composition for reducing inflammation comprising Enterococcus faecium CBG-C5(KACC 91002) as an effective ingredient is provided to reduce inflammation cheaply and simply by removing isolation and purification of conjugated linoleic acid accumulated in Enterococcus faecium CBG-C5(KACC 91002). The composition for reducing inflammation comprises destroyed Enterococcus faecium CBG-C5(KACC 91002) as an effective ingredient, wherein the concentration of the destroyed Enterococcus faecium CBG-C5(KACC 91002) in the composition is 1.25 mug/ml; and the destroyed Enterococcus faecium CBG-C5(KACC 91002) is prepared by dissolving cultured Enterococcus faecium CBG-C5(KACC 91002) in phosphate buffered saline(PBS), destroying the cultured Enterococcus faecium CBG-C5(KACC 91002) with ultrasonic wave and freeze-drying it, and suspending the freeze-dried product in PBS and sterilizing it with heating.
Abstract:
A composition for prevention of disease mediated with gap junction damage comprising 9Z, 11E conjugated linoleic acid as an effective ingredient is provided to recover the intercellular communication through the damaged gap junction, and maintain homeostasis. The composition for prevention of disease mediated with gap junction damage comprises 9Z, 11E conjugated linoleic acid as an effective ingredient, wherein the 9Z, 11E conjugated linoleic acid is produced from Enterococcus faecium CBG-C5(KACC 91002), and inhibits phosphorylation of extracellular signal-regulated kinase that is produced when the gap junctional intercellular communication is inhibited by hydrogen peroxide.