公开(公告)号：KR100727533B1

公开(公告)日：2007-06-14

申请号：KR1020060035342

申请日：2006-04-19

Applicant: 재단법인대구경북과학기술원

Inventor： 류홍근 ,  이수근 ,  손영수 ,  김현철 ,  정상원

IPC: H01L29/84

Abstract: A plate-shaped covering structure for a sensor system of a field effective transistor type and the sensor system having the same are provided to increase the reliability of an output signal by applying an electrically stable gate reference voltage to a biosensor. A metal electrode(104) serving as a reference electrode(203) is formed on an upper substrate(201), and the supper substrate is supported by a support member(202). The upper substrate is integrally formed with the support member. The metal electrode is formed in a chamber, a fluid passage, and/or a desired sidewall of a plate-shaped covering structure. The metal electrode is electrically connected to a semiconductor circuit board pad by a conductive paste or conductive material.

Abstract translation: 提供用于场效晶体管类型的传感器系统的板形覆盖结构和具有该传感器系统的传感器系统，以通过向生物传感器施加电稳定的栅极参考电压来提高输出信号的可靠性。 用作参考电极（203）的金属电极（104）形成在上基板（201）上，并且超基板由支撑构件（202）支撑。 上基板与支撑构件一体形成。 金属电极形成在板状覆盖结构的腔室，流体通道和/或期望的侧壁中。 金属电极通过导电膏或导电材料电连接到半导体电路板焊盘。

公开(公告)号：KR100819065B1

公开(公告)日：2008-04-04

申请号：KR1020060132975

申请日：2006-12-22

Applicant: 재단법인대구경북과학기술원

Inventor： 김현철 ,  이수근 ,  전원배 ,  정상원 ,  손영수 ,  류홍근

IPC: C07C323/22 ,  C07C321/20

Abstract: A trifluoroacetophenone derivative is provided to allow stable immobilization of carbonate ions to a solid substrate, to enable selective detection and measurement of carbonate ions through a surface plasma resonance process, and to solve the problems caused by ion selective membranes used in a conventional electrochemical process. A trifluoroacetophenone derivative is represented by the following formula 1 or 2. In formula 1, R is an ester group; each of X5-X8 independently represents H, halo, hydroxy, C1-C6 alkyl group or C1-C6 alkoxy group; and n is an integer of 1-24. The trifluoroacetophenone derivative is surface coated on a solid substrate for measuring carbonate ions. The solid substrate coated with the trifluoroacetophenone derivative is contacted with a liquid sample, the substrate is irradiated with light, and then the light reflectance is measured to detect or measure carbonate ions.

Abstract translation: 提供三氟乙酰苯衍生物以允许碳酸根离子稳定地固定在固体基质上，以便能够通过表面等离子体共振过程选择性地检测和测量碳酸根离子，并解决常规电化学过程中使用的离子选择性膜引起的问题。 三氟苯乙酮衍生物由下式1或2表示。在式1中，R是酯基; X5-X8各自独立地表示H，卤素，羟基，C1-C6烷基或C1-C6烷氧基; n为1-24的整数。 将三氟乙酰苯衍生物表面涂覆在用于测量碳酸根离子的固体基质上。 将涂布有三氟乙酰苯衍生物的固体基材与液体样品接触，用光照射基板，然后测量光反射率以检测或测量碳酸根离子。

公开(公告)号：KR100758822B1

公开(公告)日：2007-09-14

申请号：KR1020060035343

申请日：2006-04-19

Applicant: 재단법인대구경북과학기술원

Inventor： 이수근 ,  정상원 ,  손영수 ,  김현철 ,  류홍근

IPC: C12Q1/68

CPC classification number: C12Q1/6825

Abstract: A highly sensitive field effect transistor type bio sensor is provided to increase driving current and physical contacting area with a bio sensing target material, and enhance electric capacity of the device by structurally modifying the shape of a semiconductor substrate, and improve sensing reproducibility and accuracy of the bio sensor by increasing S/N ratio(signal to noise ratio) of the bio sensor. A highly sensitive field effect transistor type bio sensor comprises: a gate insulating membrane(203) deposited on a semiconductor substrate; a gate electrode(204) formed on the gate insulating membrane; a source region(201) and a drain region(202) formed in both sides of the gate insulating membrane; and a bio sensing membrane formed on the gate electrode, wherein a reference electrode is formed on the gate electrode and the semiconductor substrate has at least one predetermined prominence and depression part. The prominence and depression part is prepared by coating a polymer thin film with resist materials, performing an imprinting process on the resist with a micro stamp, repeating the imprinting process to form the pattern on the total substrate, removing a residual layer from the resist, and forming a predetermined shape on the semiconductor substrate with the resist pattern as a mask.

Abstract translation: 提供了一种高灵敏度的场效应晶体管型生物传感器，用于通过生物传感目标材料增加驱动电流和物理接触面积，并通过结构上改变半导体衬底的形状来提高器件的电容，并提高感测再现性和准确性 生物传感器通过增加生物传感器的S / N比（信噪比）。 高灵敏度的场效应晶体管型生物传感器包括：沉积在半导体衬底上的栅极绝缘膜（203） 形成在栅极绝缘膜上的栅电极（204）; 形成在所述栅极绝缘膜的两侧的源极区域（201）和漏极区域（202） 以及形成在所述栅电极上的生物传感膜，其中在所述栅电极上形成参考电极，并且所述半导体衬底具有至少一个预定的突起和凹陷部。 通过用抗蚀剂材料涂布聚合物薄膜，用微型印模对抗蚀剂进行印记工艺，重复印刷工艺以在总基板上形成图案，从抗蚀剂中除去残留层，制备突出部分和凹陷部分， 并且在抗蚀图案作为掩模的半导体衬底上形成预定的形状。