Abstract:
The present invention relates to a composition for preventing or treating obesity and type 2 diabetes, or hepatic steatosis and, more specifically, to a composition for preventing or treating obesity and type 2 diabetes, or hepatic steatosis, containing derivatives including a main adipose differentiation promotion factor inhibitor or biaryl amide as an active ingredient. Additionally, by inhibiting a main adipose differentiation promotion factor and increasing Wnt10b, the composition according to the present invention can control differentiation of adipocytes, and increase insulin resistance and glucose resistance, thereby being effectively used for treating obesity and type 2 diabetes, or hepatic steatosis.