公开(公告)号：KR1020150010326A

公开(公告)日：2015-01-28

申请号：KR1020130085180

申请日：2013-07-19

Applicant: 전남대학교산학협력단

Inventor： 강형식 ,  박민 ,  윤일주 ,  정윤화 ,  김상희 ,  강건욱 ,  임채민

IPC: A61K31/34 ,  A61K31/166 ,  A61K31/16 ,  A61P3/04

Abstract: The present invention relates to a composition for preventing or treating obesity and type 2 diabetes, or hepatic steatosis and, more specifically, to a composition for preventing or treating obesity and type 2 diabetes, or hepatic steatosis, containing derivatives including a main adipose differentiation promotion factor inhibitor or biaryl amide as an active ingredient. Additionally, by inhibiting a main adipose differentiation promotion factor and increasing Wnt10b, the composition according to the present invention can control differentiation of adipocytes, and increase insulin resistance and glucose resistance, thereby being effectively used for treating obesity and type 2 diabetes, or hepatic steatosis.

Abstract translation: 本发明涉及用于预防或治疗肥胖症和2型糖尿病或肝脂肪变性的组合物，更具体地，涉及用于预防或治疗肥胖症和2型糖尿病或肝脂肪变性的组合物，其包含主要脂肪分化促进的衍生物 因子抑制剂或联芳基酰胺作为活性成分。 另外，通过抑制主要的脂肪分化促进因子和增加Wnt10b，本发明的组合物可以控制脂肪细胞的分化，增加胰岛素抵抗和葡萄糖耐量，从而有效地用于治疗肥胖和2型糖尿病或肝脂肪变性 。