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公开(公告)号：AU2018217311B2
公开(公告)日：2019-09-12
申请号：AU2018217311
申请日：2018-08-17
Applicant: ACADEMIA SINICA
Inventor： CHANG TSE-WEN , CHU HSING-MAO , CHEN JOU-HAN , LIN CHUN-YU , LIN CHIEN-JEN
IPC: C07K16/46 , A61K39/395 , C12P21/08
Abstract: The present disclosure provides various core constructs. According to embodiments of the present disclosure, the core construct can be used to configure pharmaceutical molecules. In particular, the core construct may be conjugated with a functional element 5 via the click chemistry.
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2.发明申请ANTIBODIES SPECIFIC TO A NOVEL EPITOPE ON CEMX OF HUMAN MEMBRANE-BOUND IGE AND USES THEREOF IN TREATING IGE-MEDIATED DISEASES 审中-公开人体膜结合IGE CEMX上新型表位特异性抗体及其在治疗IGE介导的疾病中的应用
公开(公告)号：WO2014165028A8
公开(公告)日：2014-12-04
申请号：PCT/US2014024172
申请日：2014-03-12
Applicant: ACADEMIA SINICA , LIANG CHI MING
Inventor： CHANG TSE WEN , LIN CHIEN-JEN , LU CHIEN-SHENG
IPC: C07K16/18 , A61K39/395 , C12N15/13
CPC classification number: C07K16/4291 , C07K7/04 , C07K2317/34 , C07K2317/52 , C07K2317/73
Abstract: The present disclosure relates to anti-IgE antibodies that bind to novel antigenic epitopes of the CsmX domain, e.g., SVPHPRCHCGAGRA (SEQ ID NO:4) and the uses thereof in treating IgE-mediated diseases.
Abstract translation: 本公开涉及结合CsmX结构域的新型抗原表位（例如SVPHPRCHCGAGRA（SEQ ID NO：4））的抗IgE抗体及其在治疗IgE介导的疾病中的用途。
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公开(公告)号：SG11201705323WA
公开(公告)日：2017-07-28
申请号：SG11201705323W
申请日：2016-01-18
Applicant: ACADEMIA SINICA
Inventor： CHANG TSE-WEN , CHU HSING-MAO , CHEN JOU-HAN , LIN CHUN-YU , LIN CHIEN-JEN
IPC: A61K39/395 , C07K16/46 , C12P21/08
Abstract: The present disclosure provides various core constructs. According to embodiments of the present disclosure, the core construct can be used to configure pharmaceutical molecules. In particular, the core construct may be conjugated with a functional element via the click chemistry.
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公开(公告)号：RU2696378C2
公开(公告)日：2019-08-01
申请号：RU2017128109
申请日：2016-01-18
Applicant: ACADEMIA SINICA
Inventor： CHANG TSE-WEN , CHU HSING-MAO , CHEN JOU-HAN , LIN CHUN-YU , LIN CHIEN-JEN
IPC: C07K16/46 , C07K14/485 , C07K14/655 , C07K14/705 , C12P21/08
Abstract: Изобретениеотноситсяк областибиотехнологии, конкретнок линкерномузвену, иможетбытьиспользованов качествесшивающегосредствадляобъединенияразличныхантителилииныхбиологическиактивныхагентовв конъюгатыи построениямолекулярныхконструкцийс конкретнойкомбинациейнацеливающихи эффекторныхэлементовс применениемхимическогосинтеза, либорекомбинантнойтехнологии. 2 з.п. ф-лы, 4 ил., 72 пр.
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公开(公告)号：AU2018217311A1
公开(公告)日：2018-09-06
申请号：AU2018217311
申请日：2018-08-17
Applicant: ACADEMIA SINICA
Inventor： CHANG TSE-WEN , CHU HSING-MAO , CHEN JOU-HAN , LIN CHUN-YU , LIN CHIEN-JEN
IPC: C07K16/46 , A61K39/395 , C12P21/08
Abstract: The present disclosure provides various core constructs. According to embodiments of the present disclosure, the core construct can be used to configure pharmaceutical molecules. In particular, the core construct may be conjugated with a functional element 5 via the click chemistry.
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Patent Agency Ranking
公开(公告)号：AU2016207112A1
公开(公告)日：2017-06-15
申请号：AU2016207112
申请日：2016-01-18
Applicant: ACADEMIA SINICA
Inventor： CHANG TSE-WEN , CHU HSING-MAO , CHEN JOU-HAN , LIN CHUN-YU , LIN CHIEN-JEN
IPC: C07K16/46 , A61K39/395 , C12P21/08
Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
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公开(公告)号：CA3081058A1
公开(公告)日：2016-07-21
申请号：CA3081058
申请日：2016-01-18
Applicant: ACADEMIA SINICA
Inventor： CHANG TSE-WEN , CHU HSING-MAO , CHEN JOU-HAN , LIN CHUN-YU , LIN CHIEN-JEN
IPC: C07K14/00 , A61K47/65 , A61K47/68 , C07K5/10 , C07K7/06 , C07K7/08 , C07K14/475 , C07K14/575 , C07K14/715 , C07K16/18 , C07K16/24 , C07K16/28 , C07K16/46 , C07K19/00
Abstract: The present disclosure provides various core constructs. According to embodiments of the present disclosure, the core construct can be used to configure pharmaceutical molecules. In particular, the core construct may be conjugated with a functional element via the click chemistry.
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公开(公告)号：CA2968141C
公开(公告)日：2020-08-04
申请号：CA2968141
申请日：2016-01-18
Applicant: ACADEMIA SINICA
Inventor： CHU HSING-MAO , CHEN JOU-HAN , LIN CHUN-YU , LIN CHIEN-JEN , CHANG TSE-WEN
IPC: C07K14/00 , A61K47/65 , A61K47/68 , C07K5/10 , C07K7/06 , C07K7/08 , C07K14/475 , C07K14/575 , C07K14/715 , C07K16/18 , C07K16/24 , C07K16/28 , C07K16/46 , C07K19/00
Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Uses for treating various diseases using such molecular constructs are also disclosed.
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公开(公告)号：AU2016207112B2
公开(公告)日：2018-08-02
申请号：AU2016207112
申请日：2016-01-18
Applicant: ACADEMIA SINICA
Inventor： CHANG TSE-WEN , CHU HSING-MAO , CHEN JOU-HAN , LIN CHUN-YU , LIN CHIEN-JEN
IPC: C07K16/46 , A61K39/395 , C12P21/08
Abstract: The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed.
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10.发明公开ANTIBODIES SPECIFIC TO A NOVEL EPITOPE ON CEMX OF HUMAN MEMBRANE-BOUND IGE AND USES THEREOF IN TREATING IGE-MEDIATED DISEASES 审中-公开特异性抗体一种新的表位，其CEMX人膜IGE和用于治疗的IgE介导的疾病
公开(公告)号：EP2970454A4
公开(公告)日：2016-08-31
申请号：EP14779722
申请日：2014-03-12
Applicant: ACADEMIA SINICA TAIWAN
Inventor： CHANG TSE WEN , LIN CHIEN-JEN , LU CHIEN-SHENG
IPC: C07K16/18 , A61K39/395 , C07K16/42 , C12N15/13
CPC classification number: C07K16/4291 , C07K7/04 , C07K2317/34 , C07K2317/52 , C07K2317/73
Abstract: The present disclosure relates to anti-IgE antibodies that bind to novel antigenic epitopes of the CsmX domain, e.g., SVPHPRCHCGAGRA (SEQ ID NO: 4) and the uses thereof in treating IgE-mediated diseases.
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