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    Apparatus and method for differentiating multiple fluorescence signals by excitation wavelength
    2.
    发明专利
    Apparatus and method for differentiating multiple fluorescence signals by excitation wavelength 未知

    公开(公告)号：AU2003245302A8

    公开(公告)日：2003-12-02

    申请号：AU2003245302

    申请日：2003-05-19

    Applicant: APPLERA CORP

    Inventor： YOUNG EUGENE F ,  KING HOWARD G ,  OLDMAN MARK ,  BOEGE STEVEN J

    IPC: G01N21/25 ,  G01N21/64

    Abstract: An instrument may include an array of sample wells, a plurality of samples arranged in the array of sample wells, a plurality of light sources, a plurality of detectors, a plurality of lightpipes arranged between the plurality of samples and the plurality of detectors, and a plurality of lightpipes arranges between the plurality of light sources and the plurality of detectors. The samples include a plurality of detectable markers being capable of generating increased emission due to a presence of a target component in the sample. The detectable markers have a respective excitation wavelength range and a respective emission wavelength range. The light sources are capable of emitting a plurality of excitation wavelength ranges toward the plurality of samples to respectively excite the detectable markers. The detectors are capable of detecting an emission wavelength range emitted from the detectable markers.

    OPTICAL INSTRUMENT INCLUDUNG EXCITATION SOURCE
    3.
    发明申请
    OPTICAL INSTRUMENT INCLUDUNG EXCITATION SOURCE 审中-公开
    光学仪器附件激励源

    公开(公告)号：WO03098279A2

    公开(公告)日：2003-11-27

    申请号：PCT/US0315945

    申请日：2003-05-19

    Applicant: APPLERA CORP

    Inventor： BOEGE STEVEN J ,  OLDMAN MARK ,  YOUNG EUGENE F

    IPC: C12M1/00 ,  G01N21/25 ,  G01N21/64 ,  G01N21/78 ,  G02B

    CPC classification number: G01N21/6452 ,  G01N2021/6419 ,  G01N2021/6463 ,  G01N2021/6478 ,  G01N2201/0627 ,  G01N2201/0628

    Abstract: An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with an excitation beam generated by a light source. A collimating lens can be disposed along a beam path between the light source and the reaction regions to form bundles of collimated excitation beams, wherein each bundle corresponds to a respective reaction region. Methods of analysis using the optical instrument are also pro vided.

    Abstract translation: 提供了一种光学仪器，用于利用由光源产生的激发光束同时照射两个或更多间隔开的反应区域。 准直透镜可以沿着光源和反应区域之间的光束路径设置，以形成准直激励束的束，其中每个束对应于相应的反应区域。 还提供了使用光学仪器的分析方法。

    APPARATUS AND METHOD FOR DIFFERENTIATING MULTIPLE FLUORESCENCE SIGNALS BY EXCITATION WAVELENGTH
    4.
    发明专利
    APPARATUS AND METHOD FOR DIFFERENTIATING MULTIPLE FLUORESCENCE SIGNALS BY EXCITATION WAVELENGTH 未知

    公开(公告)号：AU2003245302A1

    公开(公告)日：2003-12-02

    申请号：AU2003245302

    申请日：2003-05-19

    Applicant: APPLERA CORP

    Inventor： KING HOWARD G ,  BOEGE STEVEN J ,  YOUNG EUGENE F ,  OLDMAN MARK

    IPC: G01N21/25 ,  G01N21/64

    Abstract: An instrument may include an array of sample wells, a plurality of samples arranged in the array of sample wells, a plurality of light sources, a plurality of detectors, a plurality of lightpipes arranged between the plurality of samples and the plurality of detectors, and a plurality of lightpipes arranges between the plurality of light sources and the plurality of detectors. The samples include a plurality of detectable markers being capable of generating increased emission due to a presence of a target component in the sample. The detectable markers have a respective excitation wavelength range and a respective emission wavelength range. The light sources are capable of emitting a plurality of excitation wavelength ranges toward the plurality of samples to respectively excite the detectable markers. The detectors are capable of detecting an emission wavelength range emitted from the detectable markers.

    Optical instrument includung excitation source
    5.
    发明专利
    Optical instrument includung excitation source 未知

    公开(公告)号：AU2003243281A8

    公开(公告)日：2003-12-02

    申请号：AU2003243281

    申请日：2003-05-19

    Applicant: APPLERA CORP

    Inventor： BOEGE STEVEN J ,  YOUNG EUGENE F ,  OLDMAN MARK

    IPC: C12M1/00 ,  G01N21/25 ,  G01N21/64 ,  G01N21/78

    Abstract: An instrument comprises a reaction region holding assembly (48) including wells for holding a plurality of spaced-apart reaction regions (40) and a light emitting source (10) adapted to direct excitation beams (15) toward the plurality of reaction regions and to simultaneously illuminate two or more of the spaced-apart reaction regions. The light emitting source includes an array of light emitting diode sources that are arranged in groups, wherein different groups of predetermined numbers of light emitting diode sources are configured to emit different excitation frequencies. The instrument further includes a collimating lens system (20) disposed along the path of excitation beams between the light emitting source and the plurality of reaction regions wherein the collimating lens system is capable of collimating the excitation beams emitted from the light emitting source into two or more spaced-apart bundles of collimated excitation beams (25) and wherein the instrument is capable of directing each of two or more bundles of collimated excitation beams toward a respective reaction region of the plurality of reaction regions.

    OPTICAL INSTRUMENT INCLUDUNG EXCITATION SOURCE
    6.
    发明专利
    OPTICAL INSTRUMENT INCLUDUNG EXCITATION SOURCE 未知

    公开(公告)号：AU2003243281A1

    公开(公告)日：2003-12-02

    申请号：AU2003243281

    申请日：2003-05-19

    Applicant: APPLERA CORP

    Inventor： BOEGE STEVEN J ,  OLDMAN MARK ,  YOUNG EUGENE F

    IPC: C12M1/00 ,  G01N21/25 ,  G01N21/64 ,  G01N21/78

    Abstract: An instrument comprises a reaction region holding assembly (48) including wells for holding a plurality of spaced-apart reaction regions (40) and a light emitting source (10) adapted to direct excitation beams (15) toward the plurality of reaction regions and to simultaneously illuminate two or more of the spaced-apart reaction regions. The light emitting source includes an array of light emitting diode sources that are arranged in groups, wherein different groups of predetermined numbers of light emitting diode sources are configured to emit different excitation frequencies. The instrument further includes a collimating lens system (20) disposed along the path of excitation beams between the light emitting source and the plurality of reaction regions wherein the collimating lens system is capable of collimating the excitation beams emitted from the light emitting source into two or more spaced-apart bundles of collimated excitation beams (25) and wherein the instrument is capable of directing each of two or more bundles of collimated excitation beams toward a respective reaction region of the plurality of reaction regions.

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