公开(公告)号：US20160229820A1

公开(公告)日：2016-08-11

申请号：US15029907

申请日：2014-10-06

Applicant: BASF SE

Inventor： Thomas ZIERKE ,  Jonas HILZENDEGEN ,  Christopher KORADIN ,  Karsten KOERBER ,  Roland GOETZ

IPC: C07D265/26 ,  C07D401/14 ,  C07D401/04 ,  C07C269/04 ,  C07C271/58

CPC classification number: C07D265/26 ,  C07C269/04 ,  C07C271/58 ,  C07D401/04 ,  C07D401/14

Abstract: The present invention relates to a process for preparing substituted isatoic acid anhydride compounds of the formula (I) in which R1 is Cl, Br, I, or CN; and R2 is CH3, Cl, Br; using anthranilic acid derivative compounds of formula (III) and/or carbamate compounds of formula (II) wherein R1 and R2 are as defined above; RAr is CH3, Cl, NO2 and n is 0, 1, 2, 3, 4 or 5; The present invention relates also to the compounds of formula (II) and to processes comprising further preceding and/or subsequent reaction steps, leading to anthranilamide pesticides or to precursors for them.

Abstract translation: 本发明涉及制备式（I）的取代的缩醛酸酐化合物的方法，其中R 1是Cl，Br，I或CN; 并且R 2是CH 3，Cl，Br; 使用式（III）的邻氨基苯甲酸衍生物化合物和/或式（II）的氨基甲酸酯化合物，其中R 1和R 2如上所定义; RAr为CH 3，Cl，NO 2，n为0,1,2,3,4或5; 本发明还涉及式（II）化合物和包括进一步的前述和/或后续反应步骤，导致邻氨基苯甲酰胺农药或其前体的方法。

公开(公告)号：US20160137615A1

公开(公告)日：2016-05-19

申请号：US14899755

申请日：2014-06-17

Applicant: BASF SE

Inventor： Timo FRASSETTO ,  Maximilian DOCHNAHL ,  Michael RACK ,  Volker MAYWALD ,  Bernd WOLF ,  Roland GOETZ ,  Philip MUELHEIMS ,  Rudolf HAEBERLE

IPC: C07D265/36

CPC classification number: C07D265/36 ,  C07C17/16 ,  C07D413/04 ,  C07C21/22

Abstract: The present invention relates to a process for manufacturing 4-propargylated amino-benzoxazinones of formula (I), comprising the following steps: step a) preparing propargyl chloride by reacting propargyl alcohol with thionyl chloride optionally in the presence of a catalyst; and step b) reacting the propargyl chloride prepared in step (a) with a NH-benzoxazinone of formula (II); wherein the variables are defined according to the description.

Abstract translation: 本发明涉及制备式（I）的4-炔丙基化苯并恶嗪酮的方法，包括以下步骤：步骤a）任选地在催化剂存在下，通过炔丙醇与亚硫酰氯反应制备炔丙基氯; 和步骤b）使步骤（a）中制备的炔丙基氯与式（II）的NH-苯并嗪酮反应; 其中根据描述定义变量。

公开(公告)号：US20200071246A1

公开(公告)日：2020-03-05

申请号：US16495424

申请日：2018-03-12

Applicant: BASF SE

Inventor： Bernd SCHAEFER ,  Roland GOETZ ,  Volker HICKMANN ,  Volker MAYWALD ,  Daniel SAELINGER

IPC: C07C17/10 ,  B01J19/12

Abstract: The present invention relates to a process for preparing bromotrichloromethane comprising a) providing bromine in chloroform; and b) radiation of the resulting solution with light in the range of 350 to 550 nm, wherein said solution of bromine in chloroform is not radiated with radiation of a wavelength below 350 nm.

公开(公告)号：US20210087207A1

公开(公告)日：2021-03-25

申请号：US16610186

申请日：2018-05-02

Applicant: BASF SE

Inventor： Harish SHINDE ,  Christopher KORADIN ,  Joachim DICKHAUT ,  Roland GOETZ ,  Eric George KLAUBER ,  Sukunath NARAYANAN ,  Dhanyakumar RAUT

IPC: C07D513/04

Abstract: The present invention relates to a process for preparing optically active compounds of formula X and intermediates thereof, wherein the variables of compound of formula X are as defined in the claims and the description.

公开(公告)号：US20200055872A1

公开(公告)日：2020-02-20

申请号：US16608290

申请日：2018-04-25

Applicant: BASF SE

Inventor： Harish SHINDE ,  Christopher KORADIN ,  Joachim DICKHAUT ,  Roland GOETZ ,  Michael RACK ,  Eric George KLAUBER ,  Sukunath NARAYANAN ,  Dhanyakumar RAUT

IPC: C07D513/04 ,  C07D417/04 ,  C07D277/32

Abstract: The present invention relates to a process for preparing optically active compounds of formula X and intermediates thereof, wherein the variables of compound of formula X are as defined in the claims or the description.

公开(公告)号：US20190270710A1

公开(公告)日：2019-09-05

申请号：US16348610

申请日：2017-11-09

Applicant: BASF SE

Inventor： Volker MAYWALD ,  Roland GOETZ ,  Daniel SAELINGER ,  Timo FRASSETTO ,  Stefan GROPP

IPC: C07D231/22

Abstract: The present invention relates to a process to produce highly purified crystalline 1-(4-chlorophenyl)pyrazol-3-ol (I).

公开(公告)号：US20190308954A1

公开(公告)日：2019-10-10

申请号：US16347414

申请日：2017-10-27

Applicant: BASF SE

Inventor： Eric George KLAUBER ,  Birgit GOCKEL ,  Sebastian SOERGEL ,  Roland GOETZ ,  Henricus Maria Martinus BASTIAANS, I ,  Jochen DIETZ ,  Joachim GEBHARDT

IPC: C07D403/12

Abstract: The present invention relates to a process for the purification of pyrazolpyridazines of formula I wherein the variables are as defined in the specification, by adding HCl to a solution of the pyrazolpyridazine in an inert solvent under non-aqueous conditions, effecting crystallization of the HCl-salt, isolating the resulting precipitate.

公开(公告)号：US20190055200A1

公开(公告)日：2019-02-21

申请号：US16074537

申请日：2017-01-25

Applicant: BASF SE

Inventor： Eric George KLAUBER ,  Michael RACK ,  Sebastian SOERGEL ,  Birgit GOCKEL ,  Roland GOETZ

IPC: C07D231/14 ,  B01J21/18 ,  B01J23/42 ,  C07D401/12 ,  C07D403/12

Abstract: The present invention relates to a catalytic process for preparing pyrazoles comprising the step of cyclizing hydrazone substituted α,β-unsaturated carbonyl compounds by reacting them with hydrogen in a reaction mixture comprising as components (a) a hydrogenation catalyst, (b) an acid selected from Brønsted acids, ammonium salts of Brønsted acids, and Lewis acids, (c) a protic solvent, and optionally (d) an aprotic solvent.

公开(公告)号：US20180141917A1

公开(公告)日：2018-05-24

申请号：US15572303

申请日：2016-05-10

Applicant: BASF SE

Inventor： Eric George KLAUBER ,  Michael RACK ,  Roland GOETZ ,  Sebastian SÖRGEL

IPC: C07D237/20 ,  C07D237/12 ,  C07D403/12 ,  C07B43/04 ,  C07B39/00 ,  C07B31/00

Abstract: Provided herein is a process for preparing a pyridazine amine compound of formula V, and a process for preparing dichloropyridazine amine compounds of formula IVa, IVb, and mixtures thereof. Further, provided herein are novel dichloropyridazine amine compounds of formula IVa, IVb, and mixtures thereof, wherein the amino group is an ethylamino group.