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    1.
    发明专利
    未知

    公开(公告)号：AT536210T

    公开(公告)日：2011-12-15

    申请号：AT02734663

    申请日：2002-06-04

    Applicant: BAXTER INT

    Inventor： BROWN RICHARD ,  MIN KYUNGYOON

    IPC: B01D21/26 ,  G01N1/10 ,  A61M1/36 ,  B04B5/04 ,  C02F1/34 ,  C02F1/38 ,  C12M1/26 ,  C12M1/34 ,  C12N1/02 ,  G01N1/36

    Abstract: Methods and apparatus for concentrating and recovering pathogens from a fluid other than blood are disclosed. The method includes concentrating the pathogens contained in the fluid by continuously feeding the fluid through one or more flexible chamber(s) and subjecting the chamber(s) to centrifugal forces. The concentrated pathogens may be re-suspended by shaking the chamber(s).

    2.
    发明专利
    未知

    公开(公告)号：DE69418454T2

    公开(公告)日：2000-01-05

    申请号：DE69418454

    申请日：1994-03-17

    Applicant: BAXTER INT

    Inventor： DENNEHEY T ,  BROWN RICHARD ,  WILLIAMSON WARREN

    IPC: A61M1/02 ,  A61M1/10 ,  A61M1/36 ,  B04B5/00 ,  F02B75/02 ,  F04B43/12 ,  F04B43/08

    Abstract: A blood processing assembly is described. The assembly comprises a separation element (16) for separating blood from a source and a fluid path (18) for conveying blood from the source to the separation element (16). The fluid path (18) includes an in-line cassette (22) having a housing (110) defining an interior, first (T4) and second (T5) pump ports on the housing (110), a first flexible tubing loop (134) extending between the first and second pump ports externally of the housing for engagement with an external peristaltic pumping element (292), a liquid port (T1 to T3,T8 to T10) on the housing attachable to a length of tubing (154) that extends externally of the housing and forms a part of the associated fluid path (18), liquid passages (F1 to F19) formed within the housing and communicating with the liquid port, the first pump port and the second pump port, and valve means (V1 to V10) formed within the housing for controlling liquid flow through the liquid passages and through the associated fluid path. The cassette also comprises a pressure sensing chamber (S1 to S4) which is formed within the housing and communicates with at least one liquid passage (F1 to F19). The sensing chamber (S1 to S4) includes means for transmitting liquid pressure present within the liquid passage to an external sensing element (PS1 to PS4).

    7.
    发明专利
    未知

    公开(公告)号：DE69310342T2

    公开(公告)日：1997-11-13

    申请号：DE69310342

    申请日：1993-03-23

    Applicant: BAXTER INT

    Inventor： BROWN RICHARD

    IPC: A61M1/02 ,  A61M1/30 ,  A61M1/36 ,  B01D17/02 ,  B01D21/24 ,  B01D21/26 ,  B04B5/00 ,  B04B5/04 ,  B04B7/08 ,  B04B13/00

    Abstract: The apparatus includes a chamber (10,31A,58,84) having a first wall (16,64) closer to the rotational axis (14,62) than a second wall (18,66). The first wall (16,64) defines a low-G side of a separation zone and the second wall (18,64) defines a high-G side of the zone. Whole blood enters a zone entry region to separate red cells toward the high-G side and platelet rich plasma (PRP) toward the low-G side. Blood flows through an inlet port (20,68) into the entry region while PRP is collected from the low-G side of the zone in the entry region through an outlet port (24,72). This enhances PRP yields.

    8.
    发明专利
    未知

    公开(公告)号：DE69310342D1

    公开(公告)日：1997-06-05

    申请号：DE69310342

    申请日：1993-03-23

    Applicant: BAXTER INT

    Inventor： BROWN RICHARD

    IPC: A61M1/02 ,  A61M1/30 ,  A61M1/36 ,  B01D17/02 ,  B01D21/24 ,  B01D21/26 ,  B04B5/00 ,  B04B5/04 ,  B04B7/08 ,  B04B13/00

    Abstract: The apparatus includes a chamber (10,31A,58,84) having a first wall (16,64) closer to the rotational axis (14,62) than a second wall (18,66). The first wall (16,64) defines a low-G side of a separation zone and the second wall (18,64) defines a high-G side of the zone. Whole blood enters a zone entry region to separate red cells toward the high-G side and platelet rich plasma (PRP) toward the low-G side. Blood flows through an inlet port (20,68) into the entry region while PRP is collected from the low-G side of the zone in the entry region through an outlet port (24,72). This enhances PRP yields.

    PREPACKAGED FLUID PROCESSING MODULE HAVING PUMP AND VALVE ELEMENTS OPERABLE IN RESPONSE TO APPLIED PRESSURES
    9.
    发明专利
    PREPACKAGED FLUID PROCESSING MODULE HAVING PUMP AND VALVE ELEMENTS OPERABLE IN RESPONSE TO APPLIED PRESSURES 未知

    公开(公告)号：DE3378612D1

    公开(公告)日：1989-01-12

    申请号：DE3378612

    申请日：1983-10-26

    Applicant: BAXTER INT

    Inventor： BILSTAD ARNOLD ,  BROWN RICHARD ,  KRUGER ROBERT

    IPC: A61M1/00 ,  A61M1/10 ,  A61M1/14 ,  A61M1/30 ,  A61M1/34 ,  B01D61/20 ,  B01D61/28 ,  F04B43/06

    Abstract: A disposable prepackaged fluid processing module (20) for deriving plasma from whole blood includes an integral housing (22) wherein anticoagulant (ACD), saline and collection containers (43,44, and 30), tubing segments (27,28,31,56,60), a membrane filter element (141), and other components (63) required in the procedure are contained. Fluid communication between the containers, tubing segments and filter element is provided by a fluid circuit formed by a panel (36) of the housing (22), and an overlying fluid-impermeable flexible sheet member (71). The fluid circuit includes pump and valve elements (130-137) which operate in response to pressures applied to the sheet member. Upon installation of the system in a related actuator apparatus (21), pneumatic actuator ports (100-107) apply pressures to the pump and valve elements to circulate fluid through the fluid circuit.

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