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1.
公开(公告)号:WO2015200239A1
公开(公告)日:2015-12-30
申请号:PCT/US2015/037055
申请日:2015-06-23
Applicant: EMD MILLIPORE CORPORATION
Inventor: GIGLIA, Sal , NHIEM, David , ASHBY LEON, Sherry , TKACIK, Gabriel
CPC classification number: B01D39/1623 , B01D2239/025 , B01D2239/0631 , B01D2239/065
Abstract: A fluid filtration device containing a composite filter media having a coarse porous polymeric nonwoven interlayer located between first and second polymeric fiber containing filter mats. The fiber diameters of the fibers in the first and second filter mats are different from each other, and each filter mat has a different pore size rating. The first and second polymeric fibers in the filter mats can be electrospun nanofibers. The interlayer has a coarser pore size when compared to the either the first or second filter mats, such that the resulting composite media has an increased dirt holding capacity compared to filter layers that are layered directly over each other without the presence of a coarse interlayer therebetween.
Abstract translation: 一种流体过滤装置,其包含复合过滤介质,该复合过滤介质具有位于包含过滤垫的第一和第二聚合物纤维之间的粗多孔聚合非织造中间层。 第一和第二过滤垫中的纤维的纤维直径彼此不同,并且每个过滤垫具有不同的孔径等级。 滤垫中的第一和第二聚合物纤维可以是电纺丝纳米纤维。 当与第一或第二过滤垫相比时,中间层具有较粗的孔径,使得与不直接层叠在一起的过滤层相比,得到的复合介质具有增加的污垢保持能力,而不存在其间的粗中间层 。
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公开(公告)号:WO2017087057A1
公开(公告)日:2017-05-26
申请号:PCT/US2016/051268
申请日:2016-09-12
Applicant: EMD MILLIPORE CORPORATION
Inventor: GIGLIA, Salvatore , NHIEM, David
CPC classification number: B01D65/10
Abstract: A method of integrity testing porous materials that is non-destructive to the material being tested. The method includes humidifying the inlet gas stream to minimize or prevent the porous material from drying out. The inlet gas stream includes at least two gases, wherein one of the gases has a different permeability in liquid than the other, such as oxygen and nitrogen. The permeate gas stream may be subjected to a driving force such as reduced pressure to increase the flow of gases and reduce test time. Multiple porous materials can be integrity tested at the same time, such as by manifolding a plurality of them together. The integrity test is capable of detecting the presence of oversized pores or defects that can compromise the retention capability of the porous material.
Abstract translation: 一种完整性测试多孔材料的方法,对被测试材料无损坏。 该方法包括加湿入口气流以最小化或防止多孔材料变干。 入口气流包括至少两种气体,其中一种气体在液体中具有不同于另一种的渗透性,例如氧气和氮气。 渗透气流可以经受诸如减压的驱动力以增加气体流量并减少测试时间。 可以同时对多种多孔材料进行完整性测试,例如通过将多个多孔材料分支在一起。 完整性测试能够检测到可能损害多孔材料保留能力的超大孔或缺陷的存在。 p>
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公开(公告)号:WO2012135679A2
公开(公告)日:2012-10-04
申请号:PCT/US2012/031549
申请日:2012-03-30
Applicant: EMD MILLIPORE CORPORATION , KAS, Onur Y. , KOZLOV, Mikhal , TKACIK, Gabriel , NHIEM, David , LEON, Sherry Ashby
Inventor: KAS, Onur Y. , KOZLOV, Mikhal , TKACIK, Gabriel , NHIEM, David , LEON, Sherry Ashby
CPC classification number: B01D69/12 , B01D71/56 , B01D2323/39 , B01D2325/02 , D01D5/0084
Abstract: A composite liquid filtration platform including a composite filtration medium featuring an electrospun polymeric nanofiber layer collected on a porous membrane. When in use, the porous membrane acts as a prefilter used upstream from the polymeric nanofiber layer to remove particles from a liquid stream flowing through the composite filtration structure. The nanofiber layer, positioned downstream from the porous membrane, is used as the retentive layer for critical filtration to provide biosafety assurance, and is responsible for capturing microorganisms like bacteria, mycoplasma or viruses. The composite liquid filtration platform provided herein exhibits permeability advantages over conventional porous membranes or nanofiber mats spun on coarse non-wovens.
Abstract translation: 一种复合液体过滤平台,其包括复合过滤介质,其特征在于在多孔膜上收集的电纺聚合物纳米纤维层。 当使用时,多孔膜用作在聚合物纳米纤维层上游使用的预过滤器,以从流过复合过滤结构的液体流中除去颗粒。 位于多孔膜下游的纳米纤维层用作临界过滤的保留层,以提供生物安全保证,并负责捕获细菌,支原体或病毒等微生物。 本文提供的复合液体过滤平台相对于在粗糙无纺布上纺出的常规多孔膜或纳米纤维垫表现出渗透性优点。
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公开(公告)号:WO2021167814A1
公开(公告)日:2021-08-26
申请号:PCT/US2021/017211
申请日:2021-02-09
Applicant: EMD MILLIPORE CORPORATION
Inventor: SATAV, Nitin , CUDDY, Martin , ZHOU, Xiaozhu , CHATTOPADHYAY, Saptarshi , TRINH, William , KAS, Onur Y. , NHIEM, David
Abstract: Provided herein are sterilizable porous filtration media and methods of making and using the same.
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公开(公告)号:WO2013013241A3
公开(公告)日:2013-01-24
申请号:PCT/US2012/047865
申请日:2012-07-23
Applicant: EMD MILLIPORE CORPORATION , KAS, Onur, Y. , KOZLOV, Mikhail , TKACIK, Gabriel , NHIEM, David , GODDARD, Philip , LEON, Sherry, Ashby
Inventor: KAS, Onur, Y. , KOZLOV, Mikhail , TKACIK, Gabriel , NHIEM, David , GODDARD, Philip , LEON, Sherry, Ashby
Abstract: A nanofiber liquid filtration medium featuring an electrospun polymeric nanofiber layer produced on a smooth non-woven substrate.
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6.
公开(公告)号:EP3160612A1
公开(公告)日:2017-05-03
申请号:EP15812262.2
申请日:2015-06-23
Applicant: EMD Millipore Corporation
Inventor: GIGLIA, Sal , NHIEM, David , ASHBY LEON, Sherry , TKACIK, Gabriel
CPC classification number: B01D39/1623 , B01D2239/025 , B01D2239/0631 , B01D2239/065
Abstract: A fluid filtration device containing a composite filter media having a coarse porous polymeric nonwoven interlayer located between first and second polymeric fiber containing filter mats. The fiber diameters of the fibers in the first and second filter mats are different from each other, and each filter mat has a different pore size rating. The first and second polymeric fibers in the filter mats can be electrospun nanofibers. The interlayer has a coarser pore size when compared to the either the first or second filter mats, such that the resulting composite media has an increased dirt holding capacity compared to filter layers that are layered directly over each other without the presence of a coarse interlayer therebetween.
Abstract translation: 包含复合过滤介质的流体过滤装置,所述复合过滤介质具有位于第一和第二聚合物纤维过滤垫之间的粗多孔聚合物非织造中间层。 第一和第二过滤垫中纤维的纤维直径彼此不同,并且每个过滤垫具有不同的孔径等级。 过滤垫中的第一和第二聚合物纤维可以是电纺纳米纤维。 与第一或第二过滤垫相比,中间层具有更粗的孔径,使得所得复合介质与直接层叠在彼此之上而不存在粗糙中间层的过滤层相比具有增加的污物容纳能力 。
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公开(公告)号:EP3377875A1
公开(公告)日:2018-09-26
申请号:EP16866797.0
申请日:2016-09-12
Applicant: EMD Millipore Corporation
Inventor: GIGLIA, Salvatore , NHIEM, David
CPC classification number: B01D65/102 , B01D65/10 , G01N15/0826 , G01N2015/084
Abstract: A method of integrity testing porous materials that is non-destructive to the material being tested. The method includes humidifying the inlet gas stream to minimize or prevent the porous material from drying out. The inlet gas stream includes at least two gases, wherein one of the gases has a different permeability in liquid than the other, such as oxygen and nitrogen. The permeate gas stream may be subjected to a driving force such as reduced pressure to increase the flow of gases and reduce test time. Multiple porous materials can be integrity tested at the same time, such as by manifolding a plurality of them together. The integrity test is capable of detecting the presence of oversized pores or defects that can compromise the retention capability of the porous material.
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公开(公告)号:EP4106906A1
公开(公告)日:2022-12-28
申请号:EP21710659.0
申请日:2021-02-09
Applicant: EMD Millipore Corporation
Inventor: SATAV, Nitin , CUDDY, Martin , ZHOU, Xiaozhu , CHATTOPADHYAY, Saptarshi , TRINH, William , KAS, Onur Y. , NHIEM, David
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公开(公告)号:EP2694196A2
公开(公告)日:2014-02-12
申请号:EP12765651.0
申请日:2012-03-30
Applicant: EMD Millipore Corporation
Inventor: KAS, Onur Y. , KOZLOV, Mikhail , TKACIK, Gabriel , NHIEM, David , LEON, Sherry Ashby , GODDARD, Philip
CPC classification number: B01D69/12 , B01D71/56 , B01D2323/39 , B01D2325/02 , D01D5/0084
Abstract: A composite liquid filtration platform including a composite filtration medium featuring an electrospun polymeric nanofiber layer collected on a porous membrane. When in use, the porous membrane acts as a prefilter used upstream from the polymeric nanofiber layer to remove particles from a liquid stream flowing through the composite filtration structure. The nanofiber layer, positioned downstream from the porous membrane, is used as the retentive layer for critical filtration to provide biosafety assurance, and is responsible for capturing microorganisms like bacteria, mycoplasma or viruses. The composite liquid filtration platform provided herein exhibits permeability advantages over conventional porous membranes or nanofiber mats spun on coarse non-wovens.
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公开(公告)号:EP2734290A2
公开(公告)日:2014-05-28
申请号:EP12814718.8
申请日:2012-07-23
Applicant: EMD Millipore Corporation
Inventor: KAS, Onur, Y. , KOZLOV, Mikhail , TKACIK, Gabriel , NHIEM, David , GODDARD, Philip , LEON, Sherry, Ashby
CPC classification number: B01D69/02 , B01D67/0004 , B01D2239/025 , B01D2239/0618 , B01D2239/0631 , B01D2239/0654 , B01D2323/39 , C02F1/444 , C02F2303/04
Abstract: A nanofiber liquid filtration medium featuring an electrospun polymeric nanofiber layer produced on a smooth non-woven substrate.
Abstract translation: 一种纳米纤维液体过滤介质,其特征在于在光滑的无纺基材上生产的电纺聚合物纳米纤维层。
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