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    NANOFIBER CONTAINING COMPOSITE STRUCTURES
    2.
    发明申请
    NANOFIBER CONTAINING COMPOSITE STRUCTURES 审中-公开
    含有纳米纤维的复合结构

    公开(公告)号：WO2012135679A2

    公开(公告)日：2012-10-04

    申请号：PCT/US2012/031549

    申请日：2012-03-30

    Applicant: EMD MILLIPORE CORPORATION ,  KAS, Onur Y. ,  KOZLOV, Mikhal ,  TKACIK, Gabriel ,  NHIEM, David ,  LEON, Sherry Ashby

    Inventor： KAS, Onur Y. ,  KOZLOV, Mikhal ,  TKACIK, Gabriel ,  NHIEM, David ,  LEON, Sherry Ashby

    IPC: B01D69/12 ,  B01D69/00 ,  B01D71/06 ,  D01D5/00 ,  B01D69/10

    CPC classification number: B01D69/12 ,  B01D71/56 ,  B01D2323/39 ,  B01D2325/02 ,  D01D5/0084

    Abstract: A composite liquid filtration platform including a composite filtration medium featuring an electrospun polymeric nanofiber layer collected on a porous membrane. When in use, the porous membrane acts as a prefilter used upstream from the polymeric nanofiber layer to remove particles from a liquid stream flowing through the composite filtration structure. The nanofiber layer, positioned downstream from the porous membrane, is used as the retentive layer for critical filtration to provide biosafety assurance, and is responsible for capturing microorganisms like bacteria, mycoplasma or viruses. The composite liquid filtration platform provided herein exhibits permeability advantages over conventional porous membranes or nanofiber mats spun on coarse non-wovens.

    Abstract translation: 一种复合液体过滤平台，其包括复合过滤介质，其特征在于在多孔膜上收集的电纺聚合物纳米纤维层。 当使用时，多孔膜用作在聚合物纳米纤维层上游使用的预过滤器，以从流过复合过滤结构的液体流中除去颗粒。 位于多孔膜下游的纳米纤维层用作临界过滤的保留层，以提供生物安全保证，并负责捕获细菌，支原体或病毒等微生物。 本文提供的复合液体过滤平台相对于在粗糙无纺布上纺出的常规多孔膜或纳米纤维垫表现出渗透性优点。

    FILTER STRUCTURE WITH ENHANCED DIRT HOLDING CAPACITY
    4.
    发明申请
    FILTER STRUCTURE WITH ENHANCED DIRT HOLDING CAPACITY 审中-公开
    具有增强的DIRT控制能力的过滤结构

    公开(公告)号：WO2015200239A1

    公开(公告)日：2015-12-30

    申请号：PCT/US2015/037055

    申请日：2015-06-23

    Applicant: EMD MILLIPORE CORPORATION

    Inventor： GIGLIA, Sal ,  NHIEM, David ,  ASHBY LEON, Sherry ,  TKACIK, Gabriel

    IPC: B01D27/14 ,  B01D29/01 ,  B01D29/05 ,  B01D29/50 ,  B01D29/56

    CPC classification number: B01D39/1623 ,  B01D2239/025 ,  B01D2239/0631 ,  B01D2239/065

    Abstract: A fluid filtration device containing a composite filter media having a coarse porous polymeric nonwoven interlayer located between first and second polymeric fiber containing filter mats. The fiber diameters of the fibers in the first and second filter mats are different from each other, and each filter mat has a different pore size rating. The first and second polymeric fibers in the filter mats can be electrospun nanofibers. The interlayer has a coarser pore size when compared to the either the first or second filter mats, such that the resulting composite media has an increased dirt holding capacity compared to filter layers that are layered directly over each other without the presence of a coarse interlayer therebetween.

    Abstract translation: 一种流体过滤装置，其包含复合过滤介质，该复合过滤介质具有位于包含过滤垫的第一和第二聚合物纤维之间的粗多孔聚合非织造中间层。 第一和第二过滤垫中的纤维的纤维直径彼此不同，并且每个过滤垫具有不同的孔径等级。 滤垫中的第一和第二聚合物纤维可以是电纺丝纳米纤维。 当与第一或第二过滤垫相比时，中间层具有较粗的孔径，使得与不直接层叠在一起的过滤层相比，得到的复合介质具有增加的污垢保持能力，而不存在其间的粗中间层 。

    ULTRPOROUS NANOFIBER MATS AND USES THEREOF
    5.
    发明申请
    ULTRPOROUS NANOFIBER MATS AND USES THEREOF 审中-公开
    超声波NANOFIBER MATS及其用途

    公开(公告)号：WO2014093345A1

    公开(公告)日：2014-06-19

    申请号：PCT/US2013/074132

    申请日：2013-12-10

    Applicant: EMD MILLIPORE CORPORATION

    Inventor： KOZLOV, Mikhail ,  TKACIK, Gabriel ,  KAS, Onur, Y. ,  POTTY, Ajish ,  PATEL, Jigneshkumar

    IPC: B01D39/14 ,  B01D39/08 ,  B01D69/06

    CPC classification number: B01D71/56 ,  A61L2/022 ,  B01D39/1623 ,  B01D61/145 ,  B01D67/0004 ,  B01D69/06 ,  B01D2239/025 ,  B01D2239/0631 ,  B01D2239/0654 ,  B01D2239/1233 ,  B01D2323/39

    Abstract: A porous electrospun polymeric nanofiber liquid filtration medium, such as an electrospun mats, used for the removal of viral particles (e.g., parvovirus) and other particles in the 18 nm to 30 nm size range from fluid streams, having a mean flow bubble point measured with perfluorohexane above 100 psi. The electrospun medium includes nanofibers having an average fiber diameter of about 6 nm to about 13 nm, and the nanofiber liquid filtration medium has a mean pore size ranging from about 0,01 um to about 0,03 um, a porosity ranging from about 80% to about 95%, a thickness ranging from about 1 um to about 100 um, and a liquid permeability greater than about 10 LMH/psi. The high porosity of the electrospun mats enable much higher water fluxes, thus reducing the time required to complete virus filtration steps on a fluid stream.

    Abstract translation: 用于从流体流中除去病毒颗粒（例如细小病毒）和其他颗粒的多孔电纺聚合物纳米纤维液体过滤介质，例如电纺丝垫，其具有测量的平均流动泡点 全氟己烷高于100psi。 电纺介质包括具有约6nm至约13nm的平均纤维直径的纳米纤维，并且纳米纤维液体过滤介质的平均孔径为约0.01-1.03μm，孔隙率为约80 ％至约95％，厚度范围为约1μm至约100μm，液体渗透性大于约10LHH / psi。 电纺毡的高孔隙度使得能够获得更高的水通量，从而减少在流体流上完成病毒过滤步骤所需的时间。

    FILTER STRUCTURE WITH ENHANCED DIRT HOLDING CAPACITY
    10.
    发明公开
    FILTER STRUCTURE WITH ENHANCED DIRT HOLDING CAPACITY 审中-公开
    具有增强的保持容量的过滤器结构

    公开(公告)号：EP3160612A1

    公开(公告)日：2017-05-03

    申请号：EP15812262.2

    申请日：2015-06-23

    Applicant: EMD Millipore Corporation

    Inventor： GIGLIA, Sal ,  NHIEM, David ,  ASHBY LEON, Sherry ,  TKACIK, Gabriel

    IPC: B01D27/14 ,  B01D29/01 ,  B01D29/05 ,  B01D29/50 ,  B01D29/56

    CPC classification number: B01D39/1623 ,  B01D2239/025 ,  B01D2239/0631 ,  B01D2239/065

    Abstract: A fluid filtration device containing a composite filter media having a coarse porous polymeric nonwoven interlayer located between first and second polymeric fiber containing filter mats. The fiber diameters of the fibers in the first and second filter mats are different from each other, and each filter mat has a different pore size rating. The first and second polymeric fibers in the filter mats can be electrospun nanofibers. The interlayer has a coarser pore size when compared to the either the first or second filter mats, such that the resulting composite media has an increased dirt holding capacity compared to filter layers that are layered directly over each other without the presence of a coarse interlayer therebetween.

    Abstract translation: 包含复合过滤介质的流体过滤装置，所述复合过滤介质具有位于第一和第二聚合物纤维过滤垫之间的粗多孔聚合物非织造中间层。 第一和第二过滤垫中纤维的纤维直径彼此不同，并且每个过滤垫具有不同的孔径等级。 过滤垫中的第一和第二聚合物纤维可以是电纺纳米纤维。 与第一或第二过滤垫相比，中间层具有更粗的孔径，使得所得复合介质与直接层叠在彼此之上而不存在粗糙中间层的过滤层相比具有增加的污物容纳能力 。

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