公开(公告)号：US20160370277A1

公开(公告)日：2016-12-22

申请号：US15253060

申请日：2016-08-31

Applicant: Fluidigm Canada Inc.

Inventor： Mitchell A. Winnik ,  Cedric Van-Caeyzeele ,  Vladimir I. Baranov

IPC: G01N15/10 ,  H01J49/00 ,  G01N33/553 ,  G01N33/68 ,  G01N33/543

CPC classification number: G01N15/1012 ,  G01N33/54313 ,  G01N33/54353 ,  G01N33/553 ,  G01N33/6848 ,  H01J49/0009 ,  Y10T436/24

Abstract: The invention relates to a new type of element encoded particles suitable for the attachment of bio molecules to enable massively multiplex bio-analytical methods, and to calibrate and tune the elemental flow cytometer mass spectrometer (FC-MS) (FIG. 1).

Abstract translation: 本发明涉及适用于附着生物分子以实现大规模多重生物分析方法以及校准和调整元流式细胞仪质谱仪（FC-MS）（图1）的新型元素编码粒子。

公开(公告)号：US20160195466A1

公开(公告)日：2016-07-07

申请号：US14983463

申请日：2015-12-29

Applicant: Fluidigm Canada Inc.

Inventor： Alexander V. Loboda ,  Dmitry R. Bandura ,  Vladimir I. Baranov

IPC: G01N15/10 ,  H01J49/04 ,  H01J49/00 ,  H01J49/40 ,  H01J49/10

CPC classification number: G01N15/1056 ,  G01N2015/0065 ,  G01N2015/1006 ,  H01J49/0009 ,  H01J49/025 ,  H01J49/04 ,  H01J49/105 ,  H01J49/40

Abstract: The inventors have improved mass cytometer to facilitate its use for the analysis of particles.

Abstract translation: 发明人已经改进了质谱仪以便于其用于分析颗粒。

公开(公告)号：US20190120745A1

公开(公告)日：2019-04-25

申请号：US16165128

申请日：2018-10-19

Applicant: Fluidigm Canada Inc.

Inventor： Alexander V. Loboda ,  Dmitry R. Bandura ,  Vladimir I. Baranov

IPC: G01N15/10 ,  H01J49/00 ,  H01J49/04 ,  H01J49/10 ,  H01J49/40 ,  H01J49/02

CPC classification number: G01N15/1056 ,  G01N2015/0065 ,  G01N2015/1006 ,  H01J49/0009 ,  H01J49/025 ,  H01J49/04 ,  H01J49/105 ,  H01J49/40

Abstract: The inventors have improved mass cytometer to facilitate its use for the analysis of particles.

公开(公告)号：US20160260598A1

公开(公告)日：2016-09-08

申请号：US15016134

申请日：2016-02-04

Applicant: FLUIDIGM CANADA INC.

Inventor： Alexander V. Loboda ,  Vladimir I. Baranov

IPC: H01J49/10 ,  H01J49/04 ,  G01N33/483 ,  G01N15/10

CPC classification number: H01J49/105 ,  G01N15/10 ,  G01N33/4833 ,  G01N2015/0065 ,  G01N2015/1006 ,  H01J49/0459 ,  H01J49/0463

Abstract: The invention relates to methods and devices for analysis of samples using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). The invention provides methods and devices in which individual ablation plumes are distinctively captured and transferred to the ICP, followed by analysis by mass cytometry.

Abstract translation: 本发明涉及使用激光烧蚀电感耦合等离子体质谱（LA-ICP-MS）分析样品的方法和装置。 本发明提供方法和装置，其中个体消融羽流被明显地捕获并转移到ICP，随后通过质谱法分析。

公开(公告)号：US09632079B2

公开(公告)日：2017-04-25

申请号：US14894287

申请日：2014-05-22

Applicant: FLUIDIGM CANADA INC.

Inventor： Dmitry R. Bandura ,  Vladimir I. Baranov ,  Alexander V. Loboda ,  Olga Ornatsky ,  Scott D. Tanner

IPC: G01N33/532 ,  G01N15/10 ,  H01J49/00 ,  G01N33/543 ,  G01N27/62 ,  G01N33/483 ,  G01N15/14

CPC classification number: G01N33/54366 ,  G01N15/1031 ,  G01N15/1404 ,  G01N15/1459 ,  G01N27/622 ,  G01N27/624 ,  G01N33/483 ,  G01N33/532 ,  G01N33/54313 ,  G01N2015/1006 ,  G01N2458/15

Abstract: The invention relates to methods and devices for molecular cytometry. The molecular cytometer is for use in the analysis of molecular tag labeled particles. In the molecular cytometer, volatile molecular tags attached to the particles, such as cells, are released as groups of molecular tags and ionized by the method of soft ionization to produce corresponding groups of molecular ions. The molecular cytometer has two detectors, one to detect the presence of the groups of molecular ions and the other to detect mobility separated molecular ions. The mobility separated molecular ions are synchronized to correspond with the groups of molecular ions.

公开(公告)号：US10598584B2

公开(公告)日：2020-03-24

申请号：US16165128

申请日：2018-10-19

Applicant: Fluidigm Canada Inc.

Inventor： Alexander V. Loboda ,  Dmitry R. Bandura ,  Vladimir I. Baranov

IPC: G01N15/10 ,  H01J49/02 ,  H01J49/00 ,  H01J49/04 ,  H01J49/10 ,  H01J49/40 ,  G01N15/00

Abstract: The inventors have improved mass cytometer to facilitate its use for the analysis of particles.

公开(公告)号：US10139332B2

公开(公告)日：2018-11-27

申请号：US14983463

申请日：2015-12-29

Applicant: Fluidigm Canada Inc.

Inventor： Alexander V. Loboda ,  Dmitry R. Bandura ,  Vladimir I. Baranov

IPC: G01N15/10 ,  H01J49/00 ,  H01J49/04 ,  H01J49/10 ,  H01J49/40 ,  H01J49/02 ,  G01N15/00

Abstract: The inventors have improved mass cytometer to facilitate its use for the analysis of particles.