公开(公告)号：WO2017070508A1

公开(公告)日：2017-04-27

申请号：PCT/US2016/058177

申请日：2016-10-21

Applicant: HAEMONETICS CORPORATION

Inventor： STACEY, Gary ,  KALESKAS, Edward

IPC: F04B43/12

CPC classification number: F04B43/1253 ,  F04B49/10

Abstract: A peristaltic pump includes a rotor and first and second rollers mounted on the rotor. The first and second rollers rotate between a disengaged, initially engaged and a fully engaged position with respect to a section of tubing. The rollers begin to occlude the tubing when in the initially engaged positon and fully occlude the tubing when in the fully engaged position. The pump also includes an encoder and a rotor controller. The encoder monitors the position of the first and second rollers as the rotor rotates. The rotor controller is in electrical communication with the encoder and controls the operation of the pump and rotor. The controller stops the rotation of the rotor in response to a stop command and based upon the monitored position of the first and second rollers such that either the first or second roller remains in the fully engaged positon.

Abstract translation: 蠕动泵包括转子和安装在转子上的第一和第二滚轮。 第一和第二辊子相对于一段管子在分离的，初始接合的和完全接合的位置之间旋转。 当处于初始接合位置时，辊子开始堵塞管道，并且当处于完全接合位置时完全堵塞管道。 该泵还包括一个编码器和一个转子控制器。 编码器在转子旋转时监测第一和第二辊的位置。 转子控制器与编码器电气连通并控制泵和转子的运行。 控制器响应于停止命令并基于第一和第二辊的监测位置停止转子的旋转，使得第一或第二辊保持在完全接合位置。

公开(公告)号：WO2017058872A1

公开(公告)日：2017-04-06

申请号：PCT/US2016/054112

申请日：2016-09-28

Applicant: HAEMONETICS CORPORATION ,  STACEY, Gary ,  SULLIVAN, James

Inventor： STACEY, Gary ,  SULLIVAN, James

IPC: G01N33/49

CPC classification number: G01N33/491

Abstract: An imaging system for a rotatable object includes an imaging unit configured to take a series of images of a portion of the rotatable object and a light source. The light source is directed at the rotatable object and is configured to generate pulses of light that illuminate the rotatable object during rotation of the rotatable object and allow the imaging unit to take the series of images of the rotatable object. The system also includes a synchronizer that monitors the rotational position of the rotatable object as it rotates, and a controller in communication with the imaging unit, the light source, and the synchronizer. The controller controls the operation of the imaging unit and/or the light source based upon the rotational position of the rotatable object such that each of the series of images is taken at the same rotational position of the rotatable object.

Abstract translation: 用于可旋转物体的成像系统包括被配置为拍摄可旋转对象的一部分和光源的一系列图像的成像单元。 光源被引导到可旋转的物体，并且被配置为在可旋转对象的旋转期间产生照亮可旋转对象的光脉冲，并允许成像单元拍摄可旋转对象的一系列图像。 该系统还包括同步器，其监视可旋转物体在旋转时的旋转位置，以及与成像单元，光源和同步器连通的控制器。 控制器基于可旋转对象的旋转位置来控制成像单元和/或光源的操作，使得每个系列图像在可旋转对象的相同旋转位置处被拍摄。

公开(公告)号：WO2008157337A1

公开(公告)日：2008-12-24

申请号：PCT/US2008/066894

申请日：2008-06-13

Applicant: TRUSTEES OF TUFTS COLLEGE ,  HAEMONETICS CORPORATION ,  ZUKERMAN, Udi ,  TZIPORI, Saul ,  STACEY, Gary

Inventor： ZUKERMAN, Udi ,  TZIPORI, Saul ,  STACEY, Gary

IPC: B01D21/26

CPC classification number: B01D21/262 ,  B01D21/302 ,  B01D2221/10 ,  B03C3/15 ,  B03C5/02 ,  B03C2201/26 ,  B04B5/10 ,  G01N1/4077

Abstract: A method for the simultaneous concentration of multiple toxins from large volumes of water. The method includes the steps of providing a disposable separation centrifuge bowl, the centrifuge bowl including a positively charged material at it's inner core. A large water sample contaminated with toxins from a group consisting of protozoa, bacteria, bacterial spores, and toxins is delivered to the centrifuge bowl. A centrifugal force is applied to the separation bowl. The water sample is concentrated to remove large particles of the toxins in the bowl due to the centrifugal forces. The concentrated water sample is passes through the positively charged inner core to capture any remaining concentrated targets by electrostatic forces and the concentrated targets are eluted.

Abstract translation: 从大量水中同时浓缩多种毒素的方法。 该方法包括提供一次性分离离心机碗的步骤，离心机碗在其内核处包含带正电荷的材料。 从原生动物，细菌，细菌孢子和毒素组成的组中被毒素污染的大量水样品被输送到离心机碗中。 离心力被施加到分离碗。 由于离心力，将水样品浓缩以除去碗中的大量毒素。 浓缩水样品通过带正电荷的内核，通过静电力捕获任何剩余的浓缩靶，并且浓缩的靶被洗脱。

公开(公告)号：WO2017075153A1

公开(公告)日：2017-05-04

申请号：PCT/US2016/059017

申请日：2016-10-27

Applicant: HAEMONETICS CORPORATION

Inventor： STACEY, Gary

IPC: G01F22/02 ,  G01F23/292 ,  G01M3/36

CPC classification number: G01L19/0092 ,  G01F22/02 ,  G01F23/292 ,  G01L11/02

Abstract: A volume measurement system for a fluid processing device includes a fluid container, an imaging unit, and a controller. The container includes a housing defining the structure of the fluid container, and a plurality of fluid chambers. The fluid chambers collect and/or store fluid from the fluid processing device, and each have a port that allows fluid to enter and/or exit the fluid chambers. The imaging unit takes images of the fluid chambers and is positioned to view a level of fluid in each of the chambers. The controller is in communication with the imaging unit and determines the volume of fluid within each of the fluid chambers based upon the viewed level of fluid in the fluid chambers.

Abstract translation: 用于流体处理装置的体积测量系统包括流体容器，成像单元和控制器。 容器包括限定流体容器的结构的壳体以及多个流体室。 流体室从流体处理装置收集和/或存储流体，并且每个流体室具有允许流体进入和/或离开流体室的端口。 成像单元拍摄流体腔室的图像并且被定位以查看每个腔室中的流体水平。 控制器与成像单元通信并基于流体室中流体的观察水平来确定每个流体室内的流体体积。

公开(公告)号：WO2010132627A2

公开(公告)日：2010-11-18

申请号：PCT/US2010/034639

申请日：2010-05-13

Applicant: HAEMONETICS CORPORATION ,  STACEY, Gary ,  PUTT, Robert, E. ,  D'ARRIGO, Michael, R. ,  LANCELOT, Robert ,  OLASKA, Timothy ,  PORTELA, Steven ,  BLACK, Frank, Jason

Inventor： STACEY, Gary ,  PUTT, Robert, E. ,  D'ARRIGO, Michael, R. ,  LANCELOT, Robert ,  OLASKA, Timothy ,  PORTELA, Steven ,  BLACK, Frank, Jason

IPC: F25D17/06

CPC classification number: F25D15/00 ,  F25D17/06 ,  F25D2317/067 ,  F25D2331/804

Abstract: A portable blood storage device includes an outer housing an inner housing. The outer housing defines the structure of the blood storage device. The inner housing is located within the outer housing and has an interior cavity for storing collected blood and/or blood components. The inner housing has an open top to allow access to the interior cavity. The storage device also has an inlet duct and a return duct located within the interior cavity. The inlet duct is fluidly connectable to a cooling device and brings conditioned air into the storage device when fluidly connected to the cooling device. The return duct is also fluidly connectable to the cooling device and returns exhaust air to the cooling device when fluidly connected.

Abstract translation: 一种便携式血液存储装置包括外壳的内壳。 外部壳体限定了血液存储装置的结构。 内壳体位于外壳体内并且具有用于存储收集的血液和/或血液成分的内部空腔。 该内壳具有敞开的顶部以允许接近内部空腔。 存储装置还具有位于内部空腔内的入口管道和返回管道。 入口管道可流体地连接到冷却装置，并且当流体地连接到冷却装置时将经调节的空气带入存储装置。 返回管道也可流体地连接到冷却装置，并在流体连接时将排气返回到冷却装置。

公开(公告)号：WO2008034102A2

公开(公告)日：2008-03-20

申请号：PCT/US2007/078561

申请日：2007-09-14

Applicant: HAEMONETICS CORPORATION ,  KNUTSON, Christopher ,  DUKE, Crystal ,  STACEY, Gary ,  MUETH, Dan ,  TANNER, Evan ,  AKCAKIR, Osman ,  FU, Haojun ,  LANCELOT, Robert ,  CHAKRABARTY, Tania ,  BRADLEY, Kenneth

Inventor： KNUTSON, Christopher ,  DUKE, Crystal ,  STACEY, Gary ,  MUETH, Dan ,  TANNER, Evan ,  AKCAKIR, Osman ,  FU, Haojun ,  LANCELOT, Robert ,  CHAKRABARTY, Tania ,  BRADLEY, Kenneth

CPC classification number: G01N33/48 ,  G01N33/54373 ,  G01N33/80

Abstract: Methods and apparatus for analyzing surface properties of particles are provided. A method for analyzing the surface properties of the particle includes a associating a first particle with a first capture zone having a specific binding affinity for a first chemical species, applying an optical force to the first particle, sensing a response of the first particle to the optical force, and using the sensed response to determine the presence, absence or quantity of the first chemical species on the first particle surface. This process may be repeated in parallel to test multiple particles. In addition to directly testing the surface properties of the particles, the method can be used in direct, indirect and competitive assays to determine the presence, absence or quantity of free or immobilized analytes. A fluidic cartridge with capture zones having avidities that are tuned for the use of optical forces is provided. A software routine for performing the method is also provided.

Abstract translation: 提供了用于分析颗粒表面性质的方法和设备。 用于分析颗粒的表面性质的方法包括将第一颗粒与对第一化学物质具有特异性结合亲和力的第一捕获区域相关联，将光学力施加到第一颗粒，感测第一颗粒对 光力，并使用感测到的响应来确定第一颗粒表面上第一化学物质的存在，不存在或数量。 该过程可以并行重复以测试多个粒子。 除了直接测试颗粒的表面特性之外，该方法还可用于直接，间接和竞争性测定，以确定游离或固定化分析物的存在，不存在或数量。 提供具有捕捉区域的射流卡盘，所述捕捉区域具有为了使用光学力而调整的灵活性。 还提供了用于执行该方法的软件例程。

公开(公告)号：EP3356819A1

公开(公告)日：2018-08-08

申请号：EP16852453.6

申请日：2016-09-28

Applicant: Haemonetics Corporation ,  Stacey, Gary ,  Sullivan, James

Inventor： STACEY, Gary ,  SULLIVAN, James

IPC: G01N33/49

CPC classification number: G01N33/491 ,  A61B5/004 ,  A61B5/0066 ,  A61B5/0261 ,  B81B2201/0257 ,  G01N21/47 ,  G01N2021/1765 ,  G02B26/0833

Abstract: An imaging system for a rotatable object includes an imaging unit configured to take a series of images of a portion of the rotatable object and a light source. The light source is directed at the rotatable object and is configured to generate pulses of light that illuminate the rotatable object during rotation of the rotatable object and allow the imaging unit to take the series of images of the rotatable object. The system also includes a synchronizer that monitors the rotational position of the rotatable object as it rotates, and a controller in communication with the imaging unit, the light source, and the synchronizer. The controller controls the operation of the imaging unit and/or the light source based upon the rotational position of the rotatable object such that each of the series of images is taken at the same rotational position of the rotatable object.

公开(公告)号：EP3368869A1

公开(公告)日：2018-09-05

申请号：EP16860756.2

申请日：2016-10-27

Applicant: Haemonetics Corporation

Inventor： STACEY, Gary

IPC: G01F22/02 ,  G01F23/292 ,  G01M3/36

CPC classification number: G01L11/02 ,  G01F22/02 ,  G01F23/292 ,  G01L19/0092

Abstract: A volume measurement system for a fluid processing device includes a fluid container, an imaging unit, and a controller. The container includes a housing defining the structure of the fluid container, and a plurality of fluid chambers. The fluid chambers collect and/or store fluid from the fluid processing device, and each have a port that allows fluid to enter and/or exit the fluid chambers. The imaging unit takes images of the fluid chambers and is positioned to view a level of fluid in each of the chambers. The controller is in communication with the imaging unit and determines the volume of fluid within each of the fluid chambers based upon the viewed level of fluid in the fluid chambers.

公开(公告)号：EP2067035A2

公开(公告)日：2009-06-10

申请号：EP07842547.7

申请日：2007-09-14

Applicant: HAEMONETICS CORPORATION

Inventor： KNUTSON, Christopher ,  DUKE, Crystal ,  STACEY, Gary ,  MUETH, Dan ,  TANNER, Evan ,  AKCAKIR, Osman ,  FU, Haojun ,  LANCELOT, Robert ,  CHAKRABARTY, Tania ,  BRADLEY, Kenneth

IPC: G01N33/543

CPC classification number: G01N33/48 ,  G01N33/54373 ,  G01N33/80

Abstract: Methods and apparatus for analyzing surface properties of particles are provided. A method for analyzing the surface properties of the particle includes a associating a first particle with a first capture zone having a specific binding affinity for a first chemical species, applying an optical force to the first particle, sensing a response of the first particle to the optical force, and using the sensed response to determine the presence, absence or quantity of the first chemical species on the first particle surface. This process may be repeated in parallel to test multiple particles. In addition to directly testing the surface properties of the particles, the method can be used in direct, indirect and competitive assays to determine the presence, absence or quantity of free or immobilized analytes. A fluidic cartridge with capture zones having avidities that are tuned for the use of optical forces is provided. A software routine for performing the method is also provided.

Abstract translation: 提供了用于分析颗粒的表面性质的方法和装置。 一种用于分析所述颗粒的表面特性的方法包括：第一颗粒与第一捕获区具有用于第一化学物质的特异性结合亲和力相关联，施加到光学力施加到第一微粒，感测所述第一颗粒的所述响应 光力，并且使用所感测响应于确定性矿第一颗粒表面上的存在，不存在或第一化学物质的量。 这个过程可以并行测试多个颗粒被重复。 除了直接检测颗粒的表面特性，该方法可以在直接，间接和竞争性测定被用于确定性矿游离或固定化分析物的存在，不存在或量。 本发明提供一种流体盒与具有亲合力捕获区没有被调谐为使用光的力。 因此，提供用于执行该方法的软件例程。

公开(公告)号：EP3365557A1

公开(公告)日：2018-08-29

申请号：EP16858319.3

申请日：2016-10-21

Applicant: Haemonetics Corporation

Inventor： STACEY, Gary ,  KALESKAS, Edward

IPC: F04B43/12

CPC classification number: F04B49/02 ,  F04B43/1253 ,  F04B49/06 ,  F04B49/10

Abstract: A peristaltic pump includes a rotor and first and second rollers mounted on the rotor. The first and second rollers rotate between a disengaged, initially engaged and a fully engaged position with respect to a section of tubing. The rollers begin to occlude the tubing when in the initially engaged positon and fully occlude the tubing when in the fully engaged position. The pump also includes an encoder and a rotor controller. The encoder monitors the position of the first and second rollers as the rotor rotates. The rotor controller is in electrical communication with the encoder and controls the operation of the pump and rotor. The controller stops the rotation of the rotor in response to a stop command and based upon the monitored position of the first and second rollers such that either the first or second roller remains in the fully engaged positon.