公开(公告)号：SG11202101607UA

公开(公告)日：2021-03-30

申请号：SG11202101607U

申请日：2019-08-30

Applicant: LIFE TECHNOLOGIES CORP

Inventor： MARKS JEFFREY ,  WOO DAVID ,  GEORGE WALLACE

IPC: G01N27/44

Abstract: A biological analysis system and an associated method are provided. The method is used for recovering off scale data in an image produced by a camera in a capillary electrophoresis instrument. The method comprises the steps of identifying bins of the image where electron counts exceed a maximum number of counts; setting an off-scale flag for the identified bins; and processing the image to obtain a recovered dye signal, based on the flag set for each bin, and using a dye matrix.

公开(公告)号：SG10202107223QA

公开(公告)日：2021-08-30

申请号：SG10202107223Q

申请日：2018-02-16

Applicant: LIFE TECHNOLOGIES CORP

Inventor： MAJUMDAR NIVEDITA ,  GEORGE WALLACE ,  MARKS JEFFREY ,  JIANG MING ,  CHANG SYLVIA ,  WOO DAVID

Abstract: Embodiments implementing selected automated quality control operations in sample processing instruments that analyze dye-labeled samples are disclosed. In some embodiments, temperature and/or pressure parameters are measured and compared to thresholds to determine whether warning should be provided and/or actions taken. Embodiments for implementing automated correction of spectral error during the instrument's normal runtime operation without requiring the user to conduct a special, separate calibration run are also disclosed.

公开(公告)号：SG11201908549RA

公开(公告)日：2019-10-30

申请号：SG11201908549R

申请日：2018-02-16

Applicant: LIFE TECHNOLOGIES CORP

Inventor： MAJUMDAR NIVEDITA ,  GEORGE WALLACE ,  MARKS JEFFREY ,  JIANG MING ,  CHANG SYLVIA ,  WOO DAVID

IPC: G01N27/447

Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 23 August 2018 (23.08.2018) WIPO I PCT oimiolo VIII °nolo OH Em OH mo mil mu° X11 ois (10) International Publication Number WO 2018/151843 A2 (51) International Patent Classification: G01N 27/447 (2006.01) (21) International Application Number: PCT/US2018/000058 (22) International Filing Date: TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: without international search report and to be republished upon receipt of that report (Rule 48.2(g)) 16 February 2018 (16.02.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/460,700 17 February 2017 (17.02.2017) US 62/463,551 24 February 2017 (24.02.2017) US (71) Applicant: LIFE TECHNOLOGIES CORPORATION [US/US]; 5823 Newton Drive, Carlsbad, CA 92008 (US). (72) Inventors: MAJUMDAR, Nivedita; c/o Life Technolo- gies Corporation, 5823 Newton Drive, Carlsbad, CA 92008 (US). GEORGE, Wallace; c/o Life Technologies Corpo- ration, 5823 Newton Drive, Carlsbad, CA 92008 (US). MARKS, Jeffrey; c/o Life Technologies Corporation, 5823 Newton Drive, Carlsbad, CA 92008 (US). JIANG, Ming; c/o Life Technologies Corporation, 5823 Newton Drive, Carlsbad, CA 92008 (US). CHANG, Sylvia; c/o Life Tech- nologies Corporation, 5823 Newton Drive, Carlsbad, CA 92008 (US). WOO, David; c/o Life Technologies Corpo- ration, 5823 Newton Drive, Carlsbad, CA 92008 (US). (74) Agent: MAURIEL, Michael; Mauriel Kapouytian Woods LLP, 15 W. 26th Street 7th Floor, New York, NY 10010 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, 71' MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, 00 1-1 00 (54) Title: AUTOMATED QUALITY CONTROL AND SPECTRAL ERROR CORRECTION FOR SAMPLE ANALYSIS INSTRU- MENTS \" (57) : Embodiments implementing selected automated quality control operations in sample processing instruments and systems C are disclosed. Embodiments for implementing automated correction of spectral error in such instruments and systems are also disclosed. These and other embodiments are further disclosed herein.