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公开(公告)号:WO2012071434A3
公开(公告)日:2012-10-04
申请号:PCT/US2011061889
申请日:2011-11-22
Applicant: LIFE TECHNOLOGIES CORP , JIANG MING , YANG CHENGYONG , WANG EUGENE CHING
Inventor: JIANG MING , YANG CHENGYONG , WANG EUGENE CHING
CPC classification number: C12Q1/6874 , G06F19/20
Abstract: A method for improving color calls or base calls utilizes current and prior cycle multi-channel intensity data from a sequencing run to model residual cycle buildup. The model is applied to correct the multi-cycle channel intensity for the current cycle. The corrected multi-cycle channel intensity is used for color calls or base calls for the current cycle.
Abstract translation: 用于改善颜色调用或碱基调用的方法利用来自测序运行的当前和先前循环多通道强度数据来模拟残余循环累积。 该模型用于修正当前周期的多周期通道强度。 修正的多周期通道强度用于当前周期的彩色呼叫或基本呼叫。
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公开(公告)号:SG10202107223QA
公开(公告)日:2021-08-30
申请号:SG10202107223Q
申请日:2018-02-16
Applicant: LIFE TECHNOLOGIES CORP
Inventor: MAJUMDAR NIVEDITA , GEORGE WALLACE , MARKS JEFFREY , JIANG MING , CHANG SYLVIA , WOO DAVID
Abstract: Embodiments implementing selected automated quality control operations in sample processing instruments that analyze dye-labeled samples are disclosed. In some embodiments, temperature and/or pressure parameters are measured and compared to thresholds to determine whether warning should be provided and/or actions taken. Embodiments for implementing automated correction of spectral error during the instrument's normal runtime operation without requiring the user to conduct a special, separate calibration run are also disclosed.
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公开(公告)号:SG11201908549RA
公开(公告)日:2019-10-30
申请号:SG11201908549R
申请日:2018-02-16
Applicant: LIFE TECHNOLOGIES CORP
Inventor: MAJUMDAR NIVEDITA , GEORGE WALLACE , MARKS JEFFREY , JIANG MING , CHANG SYLVIA , WOO DAVID
IPC: G01N27/447
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 23 August 2018 (23.08.2018) WIPO I PCT oimiolo VIII °nolo OH Em OH mo mil mu° X11 ois (10) International Publication Number WO 2018/151843 A2 (51) International Patent Classification: G01N 27/447 (2006.01) (21) International Application Number: PCT/US2018/000058 (22) International Filing Date: TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: without international search report and to be republished upon receipt of that report (Rule 48.2(g)) 16 February 2018 (16.02.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/460,700 17 February 2017 (17.02.2017) US 62/463,551 24 February 2017 (24.02.2017) US (71) Applicant: LIFE TECHNOLOGIES CORPORATION [US/US]; 5823 Newton Drive, Carlsbad, CA 92008 (US). (72) Inventors: MAJUMDAR, Nivedita; c/o Life Technolo- gies Corporation, 5823 Newton Drive, Carlsbad, CA 92008 (US). GEORGE, Wallace; c/o Life Technologies Corpo- ration, 5823 Newton Drive, Carlsbad, CA 92008 (US). MARKS, Jeffrey; c/o Life Technologies Corporation, 5823 Newton Drive, Carlsbad, CA 92008 (US). JIANG, Ming; c/o Life Technologies Corporation, 5823 Newton Drive, Carlsbad, CA 92008 (US). CHANG, Sylvia; c/o Life Tech- nologies Corporation, 5823 Newton Drive, Carlsbad, CA 92008 (US). WOO, David; c/o Life Technologies Corpo- ration, 5823 Newton Drive, Carlsbad, CA 92008 (US). (74) Agent: MAURIEL, Michael; Mauriel Kapouytian Woods LLP, 15 W. 26th Street 7th Floor, New York, NY 10010 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, 71' MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, 00 1-1 00 (54) Title: AUTOMATED QUALITY CONTROL AND SPECTRAL ERROR CORRECTION FOR SAMPLE ANALYSIS INSTRU- MENTS \" (57) : Embodiments implementing selected automated quality control operations in sample processing instruments and systems C are disclosed. Embodiments for implementing automated correction of spectral error in such instruments and systems are also disclosed. These and other embodiments are further disclosed herein.
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