Abstract:
A heart monitoring device (10) for use under emergency conditions including a portable housing, a pair of electrodes (20) and a pair of electrical wires (22) connecting the electrodes to the housing and to an electrical circuit carried therein. The electrodes are usable in two modes. One mode is a precordial mode wherein the electrodes are mounted on the exterior of the housing in commonly outwardly facing relation so as to be conveniently engageable with the skin of the chest of a user by manually engaging the housing and moving it with the electrodes fixed thereto into housing retained operative positions on the chest skin. The second mode is a non-precordial mode wherein the electrodes are removed from the housing and, preferably, self-retained within the armpits.
Abstract:
The absorption rate of t-PA in the blood is enhanced by administering it together with an absorption enhancing agent, preferably hydroxylamine or a salt therefore, most preferably hydroxylamine hydrochloride.
Abstract:
The absorption rate of t-PA in the blood is enhanced by administering it together with an absorption enhancing agent, preferably hydroxylamine or a salt thereof, most preferably hydroxylamine hydrochloride.
Abstract:
An injection device includes a generally tubular outer body (10) and a medicament cartridge assembly carried within the outer body. The cartridge assembly includes a glass container (14), a charge of medicament (36) disposed within the glass container, a plunger member (28) rearwardly confining the medicament, and a seal (22) for sealing the forward portion of the glass container. A needle (34) has a rearward end disposed proximate the seal, with the seal and needle being movable with respect to one another. A rigid needle cover member (40) is normally maintained in an inoperative position and is movable relative to said body to a protective position wherein the needle cover member extends forwardly to cover the forward end of the needle.
Abstract:
An injection device (10) comprises a plastic or metal container (26) adapted to contain a charge of medicament. The container has at least an inner surface coated with polyparaxylylene (29). A needle (40) is cooperative with the container so as to be communicable with the medicament and provides a passage through which the medicament can be forced into the flesh of an individual. A plunger (36) is disposed in the container in slidably sealed relation with the polyparaxylylene coating provided on the inner surface of the container. The plunger is movable through the container toward a generally forward end thereof to force the medicament through the needle and into the flesh of the individual.
Abstract:
An autoinjector (10) converted from an intramuscular to a subcutaneous mode of injection comprising a housing (14) having a medicament cartridge assembly (32) mounted within the housing means in a storage position for movement out of the storage position and a releasable stressed spring assembly (46) for moving the medicament cartridge assembly means out of the storage position. The stressed spring assembly is operable in response to a manual actuating procedure which does not require compression of the subcutaneous tissue to effect an intramuscular mode of injection by moving the hypodermic needle (40) of the cartridge assembly outwardly of the housing into the muscle tissue at the injection site of a user and a major portion of the liquid medicament of the cartridge assembly outwardly through the hypodermic needle into the muscle tissue of the user. An injection mode converting structure (86) is secured in a subcutaneous mode position for converting the mode of injection effected by the stressed spring assembly from the intramuscular mode of injection to a subcutaneous mode of injection in which the needle cannot extend substantially beyond subcutaneous tissue at the injection site of the user and a major portion of the liquid medicament enters into the subcutaneous tissue.
Abstract:
An automatic injecting device (10) including an elongated housing assembly (12), a stressed spring assembly (14) mounted within the housing assembly (12) so as to be released in response to a predetermined manual actuation procedure, and a medicament cartridge assembly mounted within the housing assembly in cooperating relation with the stressed spring assembly (14) comprising a hypodermic needle (62) and a medicament container (60) housing a forward (80) and rearward (88) individual dosages of different relatively incompatible liquid medicaments mounted therein and separated by a deformable stopper (66). A hub assembly (64) connects an exteriorly flanged necked down forward end portion of container (60) with the hypodermic needle. A separate fitment (90) of molded plastic material is mounted within the interior of the cylindrical glass wall of container (60) adjacent the necked down forward end portion thereof for radially inwardly deforming the stopper (82) during operation and thereby providing an axial by-pass in the periphery thereof.
Abstract:
A method of obtaining a twelve-lead electrocardiogram and a heart monitoring device (10) including a portable electrode support (12) having an array of six non-adhesive precordial electrodes (V1-V6) fixed thereon at positions corresponding to the Wilson precordial leads of an individual, a right arm electrode (RA), a left arm electrode (LA), a left leg electrode (LL), and circuitry (28) capable of producing a twelve-lead electrocardiogram. The method steps include applying the right arm, left arm, and left leg electrodes at the individual locations to obtain leads I, II, III, AVR, AVL, and AVF therefrom, engaging the array of six precordial electrodes with the individual's chest, and operating the circuitry for a time sufficient to obtain an electrocardiogram representative of leads I, II, III, AVR, AVL, AVF, V1, V2, V3, V4, V5, and V6.
Abstract:
A device for initiating reperfusion treatment of a coronary prone individual prior to the establishment of qualified direct contact personal care at a time during the early minutes or hours after the onset of heart attack symptoms and after qualified personnel have participated by telephone in the decision to initiate such treatment. The device comprises an automatic injector assembly (12) including a releasable force applying assembly (32 and 34), a safety (128, 130 and 132) normally disposed in a release preventing position movable therefrom into a release permitting position, a container or containers (44 and 96) for separately containing a plurality of separate medicament dosages including a first dosage (52) containing a clot selective coronary thrombolytic agent and a separate second dosage (98) containing a cardiac antiarrhythmic agent and one or more hypodermic needles (48 and 102). The automatic injector is operable in response to a predetermined manual actuating procedure including the movement of the safety into its release permitting position for effecting release of the releasable force applying assembly and causing the released force to be applied so as to effect (1) the movement of the hypodermic needle or needles into the muscle tissue of the individual and (2) the flow of the separate medicament dosages outwardly from the container or containers through the hypodermic needle or needles into the muscle tissue of the individual.
Abstract:
The absorption rate of proteins with medicinal properties in the blood is enhanced by administering the protein intramuscularly together with an absorption enhancing agent, preferably hydroxylamine or a salt thereof, most preferably hydroxylamine hydrochloride.