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公开(公告)号：CA2547792A1
公开(公告)日：2005-06-30
申请号：CA2547792
申请日：2004-12-16
Applicant: BASF AG
Inventor： HAEFNER STEFAN , KROEGER BURKHARD , ZELDER OSKAR , SCHROEDER HARTWIG , HABERHAUER GREGOR , RUFFER UWE , KLOPPROGGE CORINNA , GRAEF CLAUDIA ISABELLA
Abstract: The invention relates to mutant nucleic acids and proteins from the metaboli c pathway of fine chemicals, methods for the production of genetically modifie d production organisms, methods for the production of fine chemicals by cultivating said genetically modified organisms, and said genetically modifi ed organisms.
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公开(公告)号：TR200500004T2
公开(公告)日：2005-03-21
申请号：TR200500004
申请日：2000-06-23
Applicant: BASF AG
Inventor： POMPEJUS MARKUS , KROEGER BURKHARD , SCHROEDER HARTWIG , ZELDER OSKAR , HABERHAUER GREGOR
IPC: G01N33/53 , C07K20060101 , C07K14/34 , C12N20060101 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/12 , C12N9/18 , C12N9/88 , C12N15/09 , C12N15/31 , C12N15/55 , C12P20060101 , C12P13/04 , C12P13/08 , C12P21/02 , C12Q20060101 , C12Q1/68 , C12R1/15 , G01N33/566 , G01N33/569
Abstract: Isolated nucleic acid molecules, designated SMP nucleic acid molecules, which encode novel SMP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SMP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated SMP proteins, mutated SMP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of SMP genes in this organism.
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公开(公告)号：BR0213771A
公开(公告)日：2004-10-19
申请号：BR0213771
申请日：2002-10-31
Applicant: BASF AG
Inventor： ZELDER OSKAR , POMPEJUS MARKUS , SCHROEDER HARTWIG , KROEGER BURKHARD , KLOPPROGGE CORINNA , HABERHAUER GREGOR
Abstract: Isolated nucleic acid (I) that encodes any of 50 amino acid sequences (II) that have, at specific positions, an amino acid (aa) alteration. The specification includes (i) a table identifying the function of (II) and the nature/position of the amino acid exchange and (ii) sequences for (I) and (II). Independent claims are also included for the following: (1) vector that contains at least one (I); (2) host cell transfected with at least one vector of component (1); and (3) preparing fine chemicals by culturing cells of component (2).
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公开(公告)号：DE10239308A1
公开(公告)日：2004-03-11
申请号：DE10239308
申请日：2002-08-27
Applicant: BASF AG
Inventor： KROEGER BURKHARD , ZELDER OSKAR , KLOPPROGGE CORINNA , SCHROEDER HARTWIG , HAEFNER STEFAN
Abstract: Fermentative production of at least one sulfur-containing fine chemical (I) by fermenting a (I)-producing coryneform bacterium (A), concentrating (I) in medium or cells, then isolating it. (A) expresses at least one heterologous nucleotide sequence (II) that encodes a protein (III) with methionine synthase (metF) activity. An Independent claim is also included for preparation of a feed additive (B) that contains L-methionine by culturing/fermenting an L-Met producing microorganisms, removing water from the fermentation broth and optionally also up to 100 % of the biomass, then drying the treated broth to recover (B) in powdered or granular form.
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公开(公告)号：DE10219592A1
公开(公告)日：2003-11-13
申请号：DE10219592
申请日：2002-05-02
Applicant: BASF AG
Inventor： BECK CHRISTINE , SCHROEDER HARTWIG
IPC: C07K14/195 , C12N1/21 , C12N15/74
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Patent Agency Ranking
公开(公告)号：DE10154276A1
公开(公告)日：2003-05-15
申请号：DE10154276
申请日：2001-11-05
Applicant: BASF AG
Inventor： ZELDER OSKAR , POMPEJUS MARKUS , SCHROEDER HARTWIG , KROEGER BURKHARD , KLOPPROGGE CORINNA , HABERHAUER GREGOR
Abstract: The invention relates to novel nucleic acid molecules, the use thereof in the construction of bio-engineered improved microorganisms and to methods for the production of fine chemicals, especially amino acids with the aid of said bio-engineered improved microorganisms.
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公开(公告)号：DE10154270A1
公开(公告)日：2003-05-15
申请号：DE10154270
申请日：2001-11-05
Applicant: BASF AG
Inventor： ZELDER OSKAR , POMPEJUS MARKUS , SCHROEDER HARTWIG , KROEGER BURKHARD , KLOPPROGGE CORINNA , HABERHAUER GREGOR
Abstract: The invention relates to novel nucleic acid molecules, to the use thereof in the construction of genetically improved microorganisms and to a method for producing fine chemical products, in particular amino acids, by means of said genetically improved microorganisms.
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公开(公告)号：DE10154180A1
公开(公告)日：2003-05-15
申请号：DE10154180
申请日：2001-11-05
Applicant: BASF AG
Inventor： ZELDER OSKAR , POMPEJUS MARKUS , SCHROEDER HARTWIG , KROEGER BURKHARD , KLOPPROGGE CORINNA , HABERHAUER GREGOR
Abstract: The invention relates to novel nucleic acid molecules, to the use thereof in the construction of genetically improved microorganisms and to a method for producing fine chemical products, in particular amino acids, by means of said genetically improved microorganisms.
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公开(公告)号：DE10154175A1
公开(公告)日：2003-05-15
申请号：DE10154175
申请日：2001-11-05
Applicant: BASF AG
Inventor： ZELDER OSKAR , POMPEJUS MARKUS , SCHROEDER HARTWIG , KROEGER BURKHARD , KLOPPROGGE CORINNA , HABERHAUER GREGOR
Abstract: The invention relates to novel nucleic acid molecules, to their use for constructing genetically improved microorganisms and to methods for producing fine chemicals, in particular, amino acids by using these genetically modified microorganisms.
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公开(公告)号：DE1246922T1
公开(公告)日：2003-03-20
申请号：DE00942322
申请日：2000-06-27
Applicant: BASF AG
Inventor： POMPEJUS MARKUS , KROEGER BURKHARD , SCHROEDER HARTWIG , ZELDER OSKAR , HABERHAUER GREGOR
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