DEVICE FOR OPTICALLY EXCITING FLUORESCENCE
    102.
    发明申请
    DEVICE FOR OPTICALLY EXCITING FLUORESCENCE 审中-公开
    光学令人兴奋的荧光装置

    公开(公告)号:WO2017198709A1

    公开(公告)日:2017-11-23

    申请号:PCT/EP2017/061839

    申请日:2017-05-17

    Abstract: A device for optically exciting fluorescence is disclosed. The device comprises transparent substrate having first and second opposite faces and a multilayer stack disposed on the second face of the substrate. The multilayer stack comprises a first layer having first and second opposite faces and a first refractive index and a second layer having first and second opposite faces and a second refractive index. The first face of the first layer is disposed on the second face of the substrate. The first face of the second layer is disposed on the second face of the first layer such that the first layer is interposed between the second layer and the substrate. The substrate has a third refractive index. The first refractive index is less than the second refractive index and the third refractive index. The device comprises a light source carried by the first face of the substrate and arranged to emit light towards the first face of the first layer.

    Abstract translation: 公开了一种用于光学激发荧光的装置。 该装置包括具有第一和第二相对面的透明衬底以及设置在衬底的第二面上的多层叠层。 多层叠层包括具有第一和第二相对面以及第一折射率的第一层和具有第一和第二相对面以及第二折射率的第二层。 第一层的第一面设置在基底的第二面上。 第二层的第一面布置在第一层的第二面上,使得第一层介于第二层和衬底之间。 衬底具有第三折射率。 第一折射率小于第二折射率和第三折射率。 该装置包括由衬底的第一面承载的光源,该光源被设置为朝向第一层的第一面发射光。

    BELEUCHTUNGSEINRICHTUNG
    103.
    发明申请
    BELEUCHTUNGSEINRICHTUNG 审中-公开
    照明设备

    公开(公告)号:WO2014064106A1

    公开(公告)日:2014-05-01

    申请号:PCT/EP2013/072073

    申请日:2013-10-22

    Abstract: Die Erfindung betrifft eine Beleuchtungseinrichtung (100, 600) für ein optisches Gerät oder für ein Mikroskop oder für ein Makroskop (200, 300, 400, 500, 700, 800), wobei von einer ersten Beleuchtungsquelle (101, 601) emittiertes Licht über einen Beleuchtungsstrahlengang auf ein in einer Objektebene (106', 606') angeordnetes zu beleuchtendes Objekt (106, 606) gegeben wird, gekennzeichnet durch wenigstens eine in dem Beleuchtungsstrahlengang positionierbare zweite Beleuchtungsquelle (103, 603), welche transparent oder semitransparent sowie selbstleuchtend ausgebildet ist, und von der ersten Beleuchtungsquelle (101, 601) emittiertes Licht wenigstens teilweise durchlässt, wobei die Objektebene (106', 606') mit dem zu beleuchtenden Objekt (106, 606) sowohl von der ersten als auch von der zweiten Beleuchtungsquelle beleuchtet wird.

    Abstract translation: 本发明涉及一种用于光学器件或显微镜或macroscope(200,300,400,500,700,800)的照明装置(100,600),从在发射的光的第一照射源(101,601) 照明光束路径被布置在一个对象中的平面(106”,606' )被给予对象要被照射(606 106),其特征在于至少一个所述照明光束路径的第二照明源(103,603),它是透明或半透明的,和自发光的定位, 和从发射的第一照射源(101,601)的光的至少部分地穿过,其中,所述目标平面(106”,606' )与照明的对象(106,606)是由所述第一和所述第二照明源照明。

    APPARATUS AND METHOD FOR DIFFERENTIATING MULTIPLE FLUORESCENCE SIGNALS BY EXCITATION WAVELENGTH
    106.
    发明申请
    APPARATUS AND METHOD FOR DIFFERENTIATING MULTIPLE FLUORESCENCE SIGNALS BY EXCITATION WAVELENGTH 审中-公开
    用激发波长差分多个荧光信号的装置和方法

    公开(公告)号:WO2003098278A2

    公开(公告)日:2003-11-27

    申请号:PCT/US2003/015941

    申请日:2003-05-19

    IPC: G02B

    Abstract: An apparatus and method are provided for differentiating multiple detectable signals by excitation wavelength. The apparatus can include a light source that can emit respective excitation light wavelengths or wavelength ranges towards a sample in a sample retaining region, for example, in a well. The sample can contain two or more detectable markers, for example, fluorescent dyes, each of which can be capable of generating increased detectable emissions when excited in the presence of a target component. The detectable markers can have excitation wavelength ranges and/or emission wavelength ranges that overlap with the ranges of the other detectable markers. A detector can be arranged for detecting an emission wavelength or wavelength range emitted from a first marker within the overlapping wavelength range of at least one of the other markers.

    Abstract translation: 提供一种用于通过激发波长区分多个可检测信号的装置和方法。 该装置可以包括可以例如在一个井中的样品保留区域中的样品发射相应的激发光波长或波长范围的光源。 样品可以包含两种或更多种可检测的标记,例如荧光染料,其中当荧光染料在靶组分存在下被激发时,其能够产生增加的可检测的发射。 可检测标记物可以具有与其它可检测标记物的范围重叠的激发波长范围和/或发射波长范围。 可以设置检测器,用于检测在至少一个其他标记的重叠波长范围内从第一标记发射的发射波长或波长范围。

    OPTICAL SENSORS AND ARRAYS CONTAINING THIN FILM ELECTROLUMINESCENT DEVICES
    107.
    发明申请
    OPTICAL SENSORS AND ARRAYS CONTAINING THIN FILM ELECTROLUMINESCENT DEVICES 审中-公开
    光电传感器和包含薄膜电致发光器件的阵列

    公开(公告)号:WO01038857A1

    公开(公告)日:2001-05-31

    申请号:PCT/US2000/031921

    申请日:2000-11-21

    CPC classification number: G01N21/66 G01N21/7703 G01N2201/0628

    Abstract: Optical sensor, probe and array devices for detecting chemical, biological, and physical analytes. The devices include an analyte-sensitive layer (74) optically coupled to a thin film electroluminescent layer (70) which activates the analyte-sensitive layer to provide an optical response.

    Abstract translation: 用于检测化学,生物和物理分析物的光学传感器,探针和阵列装置。 器件包括光学耦合到薄膜电致发光层(70)的分析物敏感层(74),其激活分析物敏感层以提供光学响应。

    ASSAY DEVICE
    108.
    发明申请
    ASSAY DEVICE 审中-公开
    测定装置

    公开(公告)号:WO2017029526A1

    公开(公告)日:2017-02-23

    申请号:PCT/GB2016/052589

    申请日:2016-08-19

    Abstract: An assay device for the quantitative determination of the concentration of at least one analyte in a liquid sample comprises a planar emitter (2), a planar detector (3), a lateral flow membrane (4) interposed between the emitter (2) and the detector (3), a conjugate pad (5) in fluid communication with a proximal end of the lateral flow membrane (4), the conjugate pad (5) comprising optically detectable tagging particles bound to a first assay component, a sample pad (6) in fluid communication with the conjugate pad (5) and arranged to receive the liquid sample, and a wicking pad (7) in fluid communication with a distal end of the lateral flow membrane (4). The lateral flow membrane (4) is formed from a light transmissive material and is capable of transporting fluid from the conjugate pad (5) to the wicking pad (7) by capillary action. The lateral flow membrane (4) comprises at least one test region (8, 12) comprising an immobilised second assay component for retaining the tagging particles in the test region (8, 12) in dependence on the binding between the analyte, the first assay component and the second assay component in order to generate a concentration of tagging particles in the test region (8, 12) that is indicative of the concentration of the analyte in the liquid sample. The emitter (2) comprises an emission layer (9, 16) of an organic electroluminescent material and the emission layer (9, 16) is aligned with the test region (8, 12) of the lateral flow membrane 4, whereby the emitter (2) is capable of illuminating the test region (8, 12). The detector (3) comprises an absorption layer (10, 15) of an organic photovoltaic material and the absorption layer (10, 15) is aligned with the test region (8, 12) of the lateral flow membrane 4, whereby the detector (3) is capable of detecting light from the test region (8, 12).

    Abstract translation: 用于定量测定液体样品中至少一种分析物的浓度的测定装置包括平面发射体(2),平面检测器(3),介于发射体(2)和 检测器(3),与侧流膜(4)的近端流体连通的共轭垫(5),所述共轭垫(5)包括结合到第一测定组分的可光学检测的标记颗粒,样品垫(6) )与所述结合垫(5)流体连通并且被布置成接收所述液体样品,以及与所述侧流膜(4)的远端流体连通的芯吸垫(7)。 侧流膜(4)由透光材料形成,并且能够通过毛细管作用将流体从共轭垫(5)输送到芯吸垫(7)。 侧流膜(4)包括至少一个测试区域(8,12),该测试区域包括固定的第二测定组件,用于根据分析物之间的结合将第一测定法(8,12)保持在测试区域(8,12)中 组分和第二测定组分,以便产生指示液体样品中分析物浓度的测试区域(8,12)中的标记颗粒的浓度。 发射体(2)包括有机电致发光材料的发射层(9,16),并且发射层(9,16)与横向流动膜4的测试区域(8,12)对齐,由此发射极 2)能够照亮测试区域(8,12)。 检测器(3)包括有机光伏材料的吸收层(10,15),并且吸收层(10,15)与侧流膜4的测试区域(8,12)对齐,由此检测器 3)能够检测来自测试区域(8,12)的光。

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