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公开(公告)号：KR101433539B1
公开(公告)日：2014-08-27
申请号：KR1020130134953
申请日：2013-11-07
Applicant: (주)아모레퍼시픽
IPC: A61K36/484 , A61K36/48 , A61P25/00 , A61P19/00
CPC classification number: A61K31/35 , A23L2/52 , A23L33/10 , A23L33/105 , A23L33/15 , A23P10/28 , A23P10/30 , A61K9/0095 , A61K31/37 , A61K36/48
Abstract: 본 발명은 쿠메스트롤 또는 쿠메스트롤을 포함하는 콩 추출물을 유효 성분으로 포함하는 미토콘드리아 활성화용 조성물을 개시한다.
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公开(公告)号：KR101411298B1
公开(公告)日：2014-06-25
申请号：KR1020070095848
申请日：2007-09-20
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 핵 이동 신호 펩타이드 및 그의 용도에 관한 것으로서, 보다 상세하게는 서열번호 1로 기재되는 아미노산 서열을 갖는 신호 펩타이드를 코딩하는 유전자 및 이종 단백질(heterologous protein)을 코딩하는 유전자를 포함하는 발현 벡터, 상기 발현 벡터를 포함하는 이종 단백질의 핵 이동 유도용 조성물, 및 상기 조성물을 핵으로 도입하는 것을 포함하는, 이종 단백질을 핵으로 이동시키는 방법에 관한 것이다. 본 발명의 신호 펩타이드는 이종 단백질에 융합하여 그를 핵으로 이동시킬 수 있다.
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公开(公告)号：KR1020140070176A
公开(公告)日：2014-06-10
申请号：KR1020120138345
申请日：2012-11-30
Applicant: (주)아모레퍼시픽
IPC: A61K31/36 , A61K31/045 , A61P9/00
CPC classification number: A61K31/34 , A23L33/10 , A23V2002/00 , A61K31/05 , A61K31/36
Abstract: The present invention relates to a composition for preventing or treating a cardiovascular disease and, more specifically, to a composition which comprises (+)-syringaresinol for preventing or treating a cardiovascular disease. The composition can inhibit the apoptosis of myocardial cells induced by reactive oxygen by enhancing the expression of SIRT 1, thereby can have an excellent effect for preventing or alleviating the cardiovascular disease.
Abstract translation: 本发明涉及用于预防或治疗心血管疾病的组合物，更具体地，涉及包含（+） - 丁香麻醇用于预防或治疗心血管疾病的组合物。 该组合物可以通过增强SIRT1的表达来抑制由活性氧诱导的心肌细胞的凋亡，从而可以有效地预防或减轻心血管疾病。
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公开(公告)号：KR101326932B1
公开(公告)日：2013-11-11
申请号：KR1020090115024
申请日：2009-11-26
Applicant: (주)아모레퍼시픽
IPC: A61K36/282 , A61P25/28 , A23L1/30 , A61K8/97
CPC classification number: A61K36/282 , A23L33/105 , A23V2002/00 , A23V2250/21 , A23V2200/316 , A23V2200/322
Abstract: 유효성분으로, 쑥 또는 인진쑥 추출물을 함유하는 퍼옥시좀 증식체-활성 수용체 델타(Peroxisome proliferator-activated receptor-δ; PPAR-δ)의 활성을 촉진하는 조성물이 개시되며, 상기 조성물은, 근육강화, 지구력 향상, 기억력 증진, 치매 또는 파킨슨병의 예방 및 증상완화 효능이 인정된다.
인진쑥, PPAR 델타, 근육, 지구력, 기억력, 치매, 파킨슨-
公开(公告)号：KR1020130103882A
公开(公告)日：2013-09-25
申请号：KR1020120024869
申请日：2012-03-12
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: An antiobesity agent containing a hot water extract of Piper longum L. is provided to promote lipolysis of subcutaneous adipocytes and to suppress fat accumulation in the subcutaneous adipocytes, thereby preventing or suppressing obesity. CONSTITUTION: An antiobesity agent contains 1-80 wt% of a hot water extract of Piper longum L. as an active ingredient. The extract promotes the decomposition of subcutaneous fat. The obesity is caused by lipid intake. The hot water used for preparing the extract is water of 80-120°C. [Reference numerals] (AA) Degree of fat breakdown (comparing to negative control group); (BB) Hot water 10; (CC) Hot water 50; (DD) Hot water 100; (EE) Alcohol 10; (FF) Alcohol 50; (GG) Alcohol 100
Abstract translation: 目的：提供含有琵琶龙肝的热水提取物的抗肥胖剂，以促进皮下脂肪细胞的脂肪分解，并抑制皮下脂肪细胞中的脂肪蓄积，从而预防或抑制肥胖。 构成：抗肥胖剂含有1-80重量％的琵琶龙虾热水提取物作为活性成分。 提取物促进皮下脂肪的分解。 肥胖是由脂质摄入引起的。 用于制备提取物的热水为80-120℃的水。 （AA）脂肪分解程度（与阴性对照组相比）; （BB）热水10; （CC）热水50; （DD）热水100; （EE）醇10; （FF）酒精50; （GG）酒精100
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Patent Agency Ranking
公开(公告)号：KR1020130044707A
公开(公告)日：2013-05-03
申请号：KR1020110108904
申请日：2011-10-24
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A composition containing syringaresinol is provided to suppress fatty acid synthesis, to promote fatty acid oxidation, to enhance PGC 1 expression, and to prevent and treat obesity and hyperlipidemia. CONSTITUTION: A composition for preventing or treating dysbolism contains 1-80 wt% of syringaresinol as an active ingredient. Dysbolism includes disorders of carbohydrate metabolism or lipid metabolism, selected from the group consisting of obesity, type 2 diabetes, hyperlipidemia, and fatty liver. Syringaresinol is contained in extracts which is prepared using one or more selected among linseed, Phellodendron amurense Ruprecht, Acanthopanax senticosus, sesame seeds, and ginseng fruits. [Reference numerals] (AA) mRNA expression of relative SIRT 1; (BB) Fat cell; (CC) Liver cell; (DD) Muscle cell
Abstract translation: 目的：提供含有丁香胺的组合物，以抑制脂肪酸合成，促进脂肪酸氧化，增强PGC 1表达，并预防和治疗肥胖和高脂血症。 构成：用于预防或治疗dysbolism的组合物含有1-80重量％的作为活性成分的丁香胺。 嗜睡症包括选自肥胖症，2型糖尿病，高脂血症和脂肪肝的碳水化合物代谢或脂质代谢紊乱。 提取物中含有辛伐他汀，该提取物使用亚麻籽，黄柏，麻黄，芝麻，人参果实中的一种或多种进行制备。 （AA）相对于SIRT1的mRNA表达; （BB）脂肪细胞; （CC）肝细胞; （DD）肌肉细胞
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117.发明公开필발 추출물, 이소플라본을 함유하는 대두 추출물 및 Ｌ-카르니틴을 함유하는 비만 또는 고지혈증 예방용 또는 개선용 조성물 有权用于预防或治疗肥胖或含有大剂量肝素提取物，异丙肾上腺素和左旋肉碱的组合物
公开(公告)号：KR1020120037145A
公开(公告)日：2012-04-19
申请号：KR1020100098725
申请日：2010-10-11
Applicant: (주)아모레퍼시픽
IPC: A61K36/67 , A61K31/352 , A61K31/35
Abstract: PURPOSE: A composition containisng Piper longum L. extract, isoflavone, and L-carnitine is provided to reduce body fat and body weight and to enhance energy consumption. CONSTITUTION: A composition for preventing or treating obesity contains 0.0001-10 wt% of Piper longum L. extract, 0.0001-10 wt% of isoflavone, and 0.001-40 wt% of L-carnitine as an active ingredient. The composition is used for suppressing neutral fat. A composition for treating or preventing hyperlipidemia contains the Piper longum L. extract, isoflavone, and L-carnitine as an active ingredient.
Abstract translation: 目的：提供琵琶龙提取物，异黄酮和L-肉碱的组合物，以减少体脂肪和体重，增加能量消耗。 构成：用于预防或治疗肥胖症的组合物含有0.0001-10重量％的琵琶龙提取物，0.0001-10重量％的异黄酮和0.001-40重量％的左旋肉碱作为活性成分。 该组合物用于抑制中性脂肪。 用于治疗或预防高脂血症的组合物含有琵琶长叶提取物，异黄酮和L-肉毒碱作为活性成分。
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公开(公告)号：KR1020110110053A
公开(公告)日：2011-10-06
申请号：KR1020110029585
申请日：2011-03-31
Applicant: (주)아모레퍼시픽
IPC: A61K36/484 , A61K36/48 , A61P25/00 , A61P19/00
CPC classification number: A61K31/35 , A23L2/52 , A23L33/10 , A23L33/105 , A23L33/15 , A23P10/28 , A23P10/30 , A61K9/0095 , A61K31/37 , A61K36/48
Abstract: 본 발명은 쿠메스트롤 또는 쿠메스트롤을 포함하는 콩 추출물을 유효 성분으로 포함하는 미토콘드리아 활성화용 조성물을 개시한다.
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公开(公告)号：KR1020110079564A
公开(公告)日：2011-07-07
申请号：KR1020100139838
申请日：2010-12-31
Applicant: (주)아모레퍼시픽
IPC: A61K36/258 , A61P25/28 , A61P25/00
Abstract: PURPOSE: A composition containing ginseng fruit extract for mitochondria activation is provided to enhance enzyme activity and mitochondria DNA amount and to promote fatigue recovery. CONSTITUTION: A composition for mitochondria activation contains 10-90 weight% of ginseng fruit extract as an active ingredient. The composition is used for strengthening muscle. The composition is used for treating or preventing brain diseases, degenerative diseases, nervous diseases, heart diseases, liver diseases, and pancreatic diseases. The composition is a health food composition or pharmaceutical composition. The ginseng fruit extract is a pulp extract or pericarp extract.
Abstract translation: 目的：提供含有人参果实提取物用于线粒体活化的组合物，以增强酶活性和线粒体DNA量，促进疲劳恢复。 构成：用于线粒体活化的组合物含有10-90重量％的人参果实提取物作为活性成分。 该组合物用于加强肌肉。 该组合物用于治疗或预防脑疾病，退行性疾病，神经疾病，心脏病，肝脏疾病和胰腺疾病。 组合物是保健食品组合物或药物组合物。 人参果实提取物是纸浆提取物或果皮提取物。
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公开(公告)号：KR1020110060002A
公开(公告)日：2011-06-08
申请号：KR1020090116467
申请日：2009-11-30
Applicant: (주)아모레퍼시픽
IPC: A61K36/82 , A61K31/715 , A61P1/16 , A61P25/32
Abstract: PURPOSE: A composition containing post-fermented tea extract an chitooligosaccharide is provided to reduce hangover and blood acetate concentration. CONSTITUTION: A composition for relieving hangover contains post-fermented tea extract and chitooligosaccharide in a weight ratio of 1:1-1:5. The post-fermented tea extract is obtained using non-pathogenic microorganism such as Saccharomyces sp., Bacillus sp., or Aspergillus sp. A liver protective agent or fatigue recovery agent contains the composition.
Abstract translation: 目的：提供含有发酵后茶提取物的壳寡糖的组合物，以减少宿醉和血液乙酸盐浓度。 构成：用于缓解宿醉的组合物含有重量比为1：1-1：5的后发酵茶提取物和壳低聚糖。 后发酵茶提取物是使用非致病微生物如酵母属，芽孢杆菌属或曲霉属种获得的。 肝保护剂或疲劳恢复剂含有该组合物。
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