公开(公告)号：DE3260082D1

公开(公告)日：1984-05-03

申请号：DE3260082

申请日：1982-03-31

Applicant: BASF AG

Inventor： JANITSCHKE LOTHAR DR ,  HOFFMANN WERNER DR ,  ARNOLD LOTHAR DR ,  STROEZEL MANFRED ,  SCHEIPER HANS-JUERGEN

IPC: C07C45/00 ,  C07C45/74 ,  C07C49/203 ,  C07C67/00

Abstract: An improved process for the preparation of unsaturated ketones of the general formula I (I) where R1 is -CH3, and R2 and R3 are different and each is H or -CH3, by reacting an aldehyde of the general formula II (II) with a molar excess of acetone or methyl ethyl ketone at an elevated temperature in the presence of an aqueous alkali metal hydroxide solution, wherein (a) all the reactants are mixed thoroughly, (b) the temperature is kept at from 10 to 120 DEG C. above the boiling point of the lowest-boiling component and (c) the pressure is kept at from p to 100 bar, where p is the vapor pressure of the mixture at the reaction temperature. The products methylpseudoionone, dimethylpseudoionone, pseudoirone, methylpseudoirone and dimethylpseudoirone are useful scents and scent intermediates. In addition, pseudoionone is an important intermediate for the industrial preparation of vitamin A, and 6-methyl-hepta-3,5-dien-2-one is a sought-after aromatic.

公开(公告)号：DE3231189A1

公开(公告)日：1984-02-23

申请号：DE3231189

申请日：1982-08-21

Applicant: BASF AG

Inventor： JANITSCHKE LOTHAR DR ,  HOFFMANN WERNER DR

IPC: C07C49/647 ,  C07C403/00 ,  C07C131/08

公开(公告)号：DE3161961D1

公开(公告)日：1984-02-23

申请号：DE3161961

申请日：1981-06-27

Applicant: BASF AG

Inventor： JANITSCHKE LOTHAR DR ,  HOFFMANN WERNER DR

IPC: C07C45/42 ,  C07C45/51 ,  C07C47/42 ,  C07C119/06

公开(公告)号：CH636612A5

公开(公告)日：1983-06-15

申请号：CH913777

申请日：1977-07-22

Applicant: BASF AG

Inventor： BAUMANN MANFRED DR ,  HOFFMANN WERNER DR ,  FRAUNBERG KARL VON DR

IPC: C07D307/32 ,  C07D307/60 ,  C07D307/66

公开(公告)号：DE3061631D1

公开(公告)日：1983-02-17

申请号：DE3061631

申请日：1980-08-21

Applicant: BASF AG

Inventor： BARL MANFRED DR ,  DEGNER DIETER DR ,  SIEGEL HARDO DR ,  HOFFMANN WERNER DR

IPC: C07C41/00 ,  C07C41/50 ,  C07C43/315 ,  C07C45/51 ,  C07C45/67 ,  C07C47/565 ,  C07C67/00 ,  C25B3/23 ,  C25B3/29 ,  C25B3/02

Abstract: 1. A process for the preparation of a 4-tert.-butoxybenzaldehyde-dialkylacetal of the formula see diagramm : EP0025883,P4,F2 where R is alkyl of 1 to 8 carbon atoms, wherein 4-tert.-butoxytoluene is oxidized electrochemically in the presence of an alcohol of the formula ROH, where R has the above meaning.

公开(公告)号：DE2963545D1

公开(公告)日：1982-10-07

申请号：DE2963545

申请日：1979-09-28

Applicant: BASF AG

Inventor： PAUST JOACHIM DR ,  HOFFMANN WERNER DR ,  BAUMANN MANFRED DR

IPC: A61K31/19 ,  A61K31/07 ,  A61K31/20 ,  A61P35/00 ,  C07C67/00 ,  C07C401/00 ,  C07C403/00 ,  C07C403/20 ,  C07F9/54 ,  C07C175/00

公开(公告)号：CH631450A5

公开(公告)日：1982-08-13

申请号：CH813477

申请日：1977-07-01

Applicant: BASF AG

Inventor： BAUMANN MANFRED DR ,  HOFFMANN WERNER DR

IPC: C07D307/32

公开(公告)号：DE3060590D1

公开(公告)日：1982-08-12

申请号：DE3060590

申请日：1980-07-17

Applicant: BASF AG

Inventor： HIMMELE WALTER DR ,  HOFFMANN WERNER DR

IPC: C07C41/16 ,  A61K8/33 ,  A61Q13/00 ,  B01J31/00 ,  C07B61/00 ,  C07C41/00 ,  C07C41/18 ,  C07C41/26 ,  C07C43/10 ,  C07C43/13 ,  C07C45/00 ,  C07C45/49 ,  C07C45/50 ,  C07C47/198 ,  C07C67/00 ,  C11B9/00 ,  C11D3/50 ,  A61K7/46

Abstract: Bis-tert.-butoxypentanals and bis-tert.butoxypentanols of the formula where R1 and R2 are H or C1 to C4 alkyl, one X is -CHO or -CH2OH and the others are H. These compounds, which are valuable as fragrances and for use in organic syntheses are obtained by carrying out a catalytic hydroformylation, using a rhodium catalyst, of a bis-ether of the formula

公开(公告)号：CH622760A5

公开(公告)日：1981-04-30

申请号：CH935176

申请日：1976-07-21

Applicant: BASF AG

Inventor： HOFFMANN WERNER DR ,  BAUMANN MANFRED DR

IPC: A23L27/20 ,  A61K8/33 ,  A61Q13/00 ,  C07C41/00 ,  C07C41/30 ,  C07C43/14 ,  C07C43/15 ,  C07C67/00 ,  C07F9/54 ,  C11B9/00

公开(公告)号：DE2717477A1

公开(公告)日：1978-11-02

申请号：DE2717477

申请日：1977-04-20

Applicant: BASF AG

Inventor： ROSSY PHILLIP A DR ,  HOFFMANN WERNER DR ,  MUELLER NORBERT DR

IPC: C07D333/38 ,  C07D333/40

Abstract: Prepn. of thiophen carboxylic acids of formula (I) is effected by reaction of a 3-ketothiphan carboxylic acid (II) with a sulphonic acid: R4. SO2Y (III) to give a 3-sulphato deriv. then reacting the product with an alkali metal polysulphide. The resulting cpd. is treated with a sulphuric acid chloride or bromide or with Cl2 to give modified polysulphide which is finally treated with ahalogen and water. In the formula R is CO2R3 or H; R2 is H whe R' is -CO2R3; or R' is -CO2R3 when R' is H; R3 is H or an aliphatic group; X is halo; R4 is an aliphatic or aromatic group; Y is halo, the group OR3 or a group -O3S.R4. Provides simple, more economic process for prodn. of (I) which is intermediate for thiophen-saccharin sweetening agents. A typical cpd. methyl-3-chlorosulphonylthiophen-4-carboxylate, was prepd. by the 4-stage process from methyl 3-hydroxy-dihydrothiophen-4-carboxylate.