公开(公告)号：WO1994015527A1

公开(公告)日：1994-07-21

申请号：PCT/US1994000307

申请日：1994-01-10

Applicant: AXELGAARD, Jens

IPC: A61B05/04

CPC classification number: A61N1/0492 ,  A61B5/0408 ,  A61N1/0428 ,  A61N1/0452 ,  A61N1/0456 ,  A61N1/0472 ,  A61N1/0476

Abstract: A medical electrode system (10) includes an electrically non-conductive backing material (12) and a flexible, electrically conductive patch (14) disposed on the backing material (12). An electrically non-conductive facing material (16) is disposed over the patch which includes an aperture (24) therein for exposing a portion of the patch (14), said aperture (24) having a maximum dimension smaller than a minimum dimension of the patch (14). A lead wire (20) electrically connected to the patch (14) and a separate electrically conductive gel pad (30) is provided for releasably coupling the patch to a body part (34), the gel pad (30) having a minimum dimension larger than the aperture's maximum dimension and formed from a material enabling the gel means to be removed, intact, from said body part and patch. The gel pad (30) may further include a drug suitable for iontophoretic delivery. A strap system (76, 78) enables the patches (14) and backing material (12) to be applied in a compressing manner on a body part, and in one embodiment, the entire system is both stretchable and flexible.

Abstract translation: 医疗电极系统（10）包括非导电背衬材料（12）和设置在背衬材料（12）上的柔性导电贴片（14）。 一种非导电的面向材料（16）设置在该贴片上方，该贴片包括其中的孔（24），用于暴露该贴片（14）的一部分，所述孔（24）的最大尺寸小于 补丁（14）。 电连接到贴片（14）的引线（20）和单独的导电凝胶垫（30）被提供用于将贴片可释放地耦合到主体部分（34），所述凝胶垫（30）的最小尺寸较大 比孔的最大尺寸形成并且使得能够完整地从所述主体部分和贴片去除凝胶装置的材料。 凝胶垫（30）还可以包括适合于离子电渗疗法输送的药物。 带状系统（76,78）使得贴片（14）和背衬材料（12）能够以压缩方式施加在身体部分上，并且在一个实施例中，整个系统既可伸展又灵活。

公开(公告)号：WO1994012098A1

公开(公告)日：1994-06-09

申请号：PCT/US1993011193

申请日：1993-11-18

Applicant: CARDIAC PATHWAYS CORPORATION

Inventor： CARDIAC PATHWAYS CORPORATION ,  IMRAN, Mir, A.

IPC: A61B05/04

CPC classification number: A61B5/6859 ,  A61B5/0422 ,  A61B18/1492 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/00946 ,  A61N1/056

Abstract: A catheter comprising a flexible elongate tubular member (22) having proximal and distal extremities. A deflection tip (31) is carried by the distal extremity of the flexible tubular member and has a curved deflecting surface (29). The flexible elongate member has a plurality of lumens (26) therein extending through the distal extremity of the flexible elongate member and opening onto the curved deflecting surface of the deflecting tip. A plurality of arms (41) are slidably mounted in the lumens. Each of the arms has a plurality of electrodes (57) spaced-apart longitudinally thereon. A control mechanism (101) is secured to the proximal extremity of the flexible elongate member and is coupled to the plurality of arms for moving the distal extremities of the arms into engagement with the deflection tip to cause the arms to deflect proximally and outwardly from the deflection tip.

Abstract translation: 导管，其包括具有近端和远端的柔性细长管状构件（22）。 偏转尖端（31）由柔性管状构件的远端承载并且具有弯曲的偏转表面（29）。 柔性细长构件在其中延伸穿过柔性细长构件的远端并且在偏转尖端的弯曲偏转表面上开口的多个腔（26）。 多个臂（41）可滑动地安装在腔内。 每个臂具有在其上纵向间隔开的多个电极（57）。 控制机构（101）固定到柔性细长构件的近端，并且联接到多个臂，用于将臂的远端延伸成与偏转末端接合，以使臂从近侧和向外偏转 偏转尖

公开(公告)号：WO1994008507A1

公开(公告)日：1994-04-28

申请号：PCT/US1993009763

申请日：1993-10-13

Applicant: ASPECT MEDICAL SYSTEMS, INC.

Inventor： ASPECT MEDICAL SYSTEMS, INC. ,  SHAMBROOM, John, R.

IPC: A61B05/04

CPC classification number: A61B5/6843 ,  A61B5/0006 ,  A61B5/0476 ,  A61B5/7217 ,  G06F19/00 ,  G16H40/63 ,  Y10S128/901 ,  Y10S128/902

Abstract: An EEG monitor utilizes a portable acquisition module (14) and a substantially stationary processing module (12). The EEG signals are acquired and converted to an oversampled stream of digital signals by a sigma-delta modulator (64) located in the data acquisition module. The signals are then filtered by a decimation filter (62) located in the processing module. Additional means are also provided to monitor the electrode leads to detect when the leads become unplugged. The monitor provides all power to the data acquisition module over a single twisted line which transmits data as well.

Abstract translation: EEG监视器利用便携式采集模块（14）和基本上固定的处理模块（12）。 通过位于数据采集模块中的Σ-Δ调制器（64），获取EEG信号并将其转换为过采样的数字信号流。 然后通过位于处理模块中的抽取滤波器（62）对信号进行滤波。 还提供附加装置来监测电极引线以检测引线何时拔出。 显示器通过单个传输数据的双绞线向数据采集模块提供所有电源。

公开(公告)号：WO1994005201A1

公开(公告)日：1994-03-17

申请号：PCT/US1993008275

申请日：1993-09-02

Applicant: TANSEY, Michael, A.

IPC: A61B05/04

CPC classification number: A61B5/7257 ,  A61B5/0482 ,  A61B5/742

Abstract: A biofeedback system (10) provides detection of bioelectric signals in a range of 0-90 Hz. A bioelectric signal (26) is amplified by a preamplifier (22). The composite amplitude of the amplified signal (24) is calculated by performing a fast Fourier transform on the amplified signal to calculate amplitudes of bandwidths in the range of the detected signal. Particular bandwidths of interest can be selected and displayed on a computer (26). The display permits training of the person being monitored with audio or verbal feedback.

Abstract translation: 生物反馈系统（10）提供在0-90Hz范围内的生物电信号的检测。 生物电信号（26）由前置放大器（22）放大。 通过对放大信号执行快速傅里叶变换来计算放大信号（24）的合成幅度，以计算检测信号范围内的带宽幅度。 感兴趣的特定带宽可以选择并显示在计算机（26）上。 该显示允许使用音频或口头反馈对被监视者进行训练。

公开(公告)号：WO1993022966A1

公开(公告)日：1993-11-25

申请号：PCT/US1993004914

申请日：1993-05-20

Applicant: AXELGAARD, Jens

IPC: A61B05/04

CPC classification number: A61N1/0456 ,  A61B5/04085 ,  A61N1/0452 ,  A61N1/0492

Abstract: An electrode system includes a nonconductive material (12) and straps (36) for positioning and holding the nonconductive material (12) along with lead wires (30) for electrically connecting the fabric patches (14) to a remote monitor or pulse generator. An electrically conductive adhesive gel pad (16) is provided for releasably coupling the flexible conductive fabric patch (14) to the body part. The pad (16) is selectively removable from the fabric patch (14), enabling removal of the patch (14) from the gel pad (16) while the latter remains adhered to a body part. This facilitates release of the conductive fabric patch (14) and separate disposal of the adhesive gel pad (16).

公开(公告)号：WO1993014695A1

公开(公告)日：1993-08-05

申请号：PCT/US1993000870

申请日：1993-02-03

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  LEUCHTER, Andrew, F. ,  COOK, Ian, A.

IPC: A61B05/04

CPC classification number: A61B5/048 ,  A61B5/4064 ,  A61B5/4088

Abstract: Determining the brain condition of a human between normal and abnormal as determined by dementia, and selectively between dementia of the Alzheimer's-type and multi-infarct dementia is effected. Measures of electrical output, spectral ratio and coherence value of the brain are determined. Selected scores are applied to the electrical output, spectral ratio and coherence values. A relationship between the scores and additionally the scored value of a coherence ratio are effected to obtain a diagnostic evaluation. Measurements are taken by electrodes (13).

公开(公告)号：WO1993002616A1

公开(公告)日：1993-02-18

申请号：PCT/US1991005705

申请日：1991-08-09

Applicant: SRD SHORASHIM MEDICAL, LTD. ,  PEARLMAN, Andrew, L.

Inventor： SRD SHORASHIM MEDICAL, LTD.

IPC: A61B05/04

CPC classification number: A61B5/04284 ,  A61B5/04085 ,  A61B5/0448 ,  A61B5/0478 ,  A61B5/0496 ,  A61B5/1103 ,  A61B5/161 ,  A61B5/4362 ,  A61B5/6803 ,  A61B5/6806 ,  A61B5/6814 ,  A61B5/6821 ,  A61B5/7207 ,  A61B2503/02 ,  A61B2560/0228 ,  A61B2560/0487 ,  A61B2562/0214 ,  A61B2562/166 ,  A61B2562/247

Abstract: Apparatus for mounting electrodes (10) on a human body in order to obtain human biosignals is disclosed. The apparatus includes close fitting clothing apparatus (70), a plurality of electrodes (10) mounted to the close fitting clothing apparatus (70), removable cover sheet apparatus (78) for providing a sterile interface between the skin and at least one of the electrodes (10) and joining apparatus for joining the removable cover sheet apparatus (78) to at least one of the plurality of electrodes (10). A variety of applications of the apparatus are also disclosed, including apparatus (130) for detecting drowsiness in a subject and for alerting the subject as a result and a fetal biosignal probe (200).

Abstract translation: 公开了用于将电极（10）安装在人体上以获得人体生物信号的装置。 该装置包括紧密装配的衣物装置（70），安装在紧密装配装置（70）上的多个电极（10），可移除的覆盖片装置（78），用于提供皮肤与至少一个 电极（10）和用于将可移除覆盖片装置（78）连接到多个电极（10）中的至少一个的接合装置。 还公开了该装置的各种应用，包括用于检测受试者嗜睡的装置（130）和作为结果的对象的提示和胎儿生物信号探针（200）。

公开(公告)号：WO1992014400A1

公开(公告)日：1992-09-03

申请号：PCT/US1992001202

申请日：1992-02-13

Applicant: PRISM IMAGING, INC.

Inventor： PRISM IMAGING, INC. ,  FREELAND, John, C.

IPC: A61B05/04

CPC classification number: A61B8/543 ,  A61B5/0456 ,  A61B8/08 ,  A61B8/463 ,  G01S7/52034 ,  G01S7/52074

Abstract: Heart performance is evaluated by collecting ultrasound images of at least one chamber of the heart of a patient after peak exercice (204, 206). The images are subsequently displayed and analyzed to determine the presence and degree of heart disease, such as coronary artery disease (CAD). Collecting (212) the images is done continuously at a rate of at least eight images per heart beat synchronized to a predetermined point in each heart beat over a time period (214) which is normally sufficient to capture ischemic events resulting form the peak exercise (204, 206). Each image thus synchronized (212) represents a similar condition of each heart beat, thereby facilitating accurate comparisons. Collecting of images can be interrupted to eliminate blank or obscured images while the ultrasound sensor is repositioned (216, 224). The collected images can be displayed and subsequently analyzed to determine the presence and degree of heart disease by comparing the images from successive heart beats.

公开(公告)号：WO1992011806A1

公开(公告)日：1992-07-23

申请号：PCT/US1991009777

申请日：1991-12-30

Applicant: ARZCO MEDICAL ELECTRONICS, INC.

Inventor： ARZCO MEDICAL ELECTRONICS, INC. ,  BILOF, Richard, M. ,  METZGER, William, T. ,  BUINEVICIUS, Rimas

IPC: A61B05/04

CPC classification number: A61N1/0517

Abstract: A swallowable electrode (10) or an esophageal catheter (201) are formed with a porous (111) or roughened region (113) capable of receiving a cream or jell form of topical anesthetic. The anesthetic can be covered with a dissolvable medium. Located on each side of the anesthetic is a metal conductor (107, 109) coupled to a flexible wire (103) extending from the device. Upon positioning of the metal members in an individual's esophagus, adjacent a posterior heart surface, the protective medium dissolves (102) exposing the topical anesthetic to portions of the esophagus adjacent to the two conducting members (107, 109). A lumen (221) in the catheter can be provided to deliver the anesthetic to the esophagus. The exposed anesthetic can be absorbed by the adjacent region of the esophagus thereby providing for more comfortable esophageal cardiac pacing.

Abstract translation: 吞咽电极（10）或食道导管（201）形成有多孔（111）或粗糙区域（113），能够接受霜剂或凝胶形式的局部麻醉剂。 麻醉剂可以用可溶解的介质覆盖。 位于麻醉剂的每一侧的是连接到从装置延伸的柔性线（103）的金属导体（107,109）。 当将金属构件定位在个体食道中，邻近后心脏表面时，保护介质溶解（102）将局部麻醉剂暴露于与两个导电构件（107,109）相邻的部分食道。 可以提供导管中的内腔（221）以将麻醉剂输送到食道。 暴露的麻醉剂可以被食道的相邻区域吸收，从而提供更舒适的食管心脏起搏。

公开(公告)号：WO1990011719A1

公开(公告)日：1990-10-18

申请号：PCT/US1990001695

申请日：1990-03-30

Applicant: KEUSCH, Preston ,  MURDOCK, Keith, A. ,  CZAP, Christine, A. ,  LENNON, Linda

IPC: A61B05/04

CPC classification number: C08J3/28 ,  A61B5/04087 ,  A61B2018/00107 ,  A61L15/58 ,  A61L24/001 ,  A61L24/0031 ,  C08J2300/10 ,  C08L2666/02 ,  C09J139/06 ,  C09J171/02 ,  H01M6/22 ,  C08L71/02 ,  C08L39/06

Abstract: The non-stringy hydrogels of this invention are comprised of a homogeneous uniform mixture of water and at least one water-soluble high molecular weight polymer. Suitable mixtures may be derived from poly(ethylene oxide) and water or poly(vinyl pyrrolidone), a viscosity-enhancing hydrophilic polymer and water, and further, may optionally contain an effective amount of a water-soluble electrolyte to provide conductive non-stringy materials. These polymeric mixtures which are crosslinked by exposure to radiant energy provide gel-like solids which are sufficiently tacky and adhesive to adhere to the subjects' skin and yet are substantially non-stringy and non-aggressive such that contact with such hydrogels imparts less discomfort to the user. In addition, the consumer utilizing the products of this invention would not experience the objectionable sticky, stringy sensation associated with existing conductive adhesive gels.