公开(公告)号：WO1998027864A1

公开(公告)日：1998-07-02

申请号：PCT/US1997023624

申请日：1997-12-19

Applicant: ASPECT MEDICAL SYSTEMS, INC.

Inventor： ASPECT MEDICAL SYSTEMS, INC. ,  GREENWALD, Scott, D. ,  SMITH, Charles, P.

IPC: A61B05/0476

CPC classification number: A61B5/0476 ,  A61B5/7217

Abstract: The disclosed filter (120) removes cardiac artifacts (310) from signals representative of a patient's cerebral activity. The filter preferably replaces portions of the signal including artifacts with temporally adjacent artifact free portions.

Abstract translation: 所公开的过滤器（120）从代表患者脑活动的信号中去除心脏假象（310）。 滤波器优选地替换信号的部分，包括与时间上相邻的无伪影部分的伪影。

公开(公告)号：WO1993007804A1

公开(公告)日：1993-04-29

申请号：PCT/US1992009074

申请日：1992-10-23

Applicant: ASPECT MEDICAL SYSTEMS, INC.

Inventor： ASPECT MEDICAL SYSTEMS, INC. ,  CHAMOUN, Nassib, G. ,  MEAD, Peter, A. ,  CHIANG, Hsing-Hsing ,  SAI NI, Vikas

IPC: A61B05/04

CPC classification number: A61B5/4821 ,  A61B5/048 ,  A61B5/16 ,  A61B5/725 ,  A61B5/7253 ,  A61B5/7257 ,  G06F19/00 ,  G16H15/00

Abstract: A system and method to obtain (19) unipolar EEG signals from electrodes (13) attached to a patient's head (14). The EEG signals are detected by the electrodes and transmitted over a patient cable (16) to the EEG data acquisition and analysis system (12). The system (12) generates all power spectrum, bispectrum, and higher-order spectrum arrays. These arrays are then used in conjunction with clinically predetermined coefficient arrays to produce diagnostic indices. These indices are sent to the host computer (18) and are displayed on the graphics display (2). Printed output of the diagnostic index is also available on the hard copy output device (22) which is connected to the microcomputer (18). The operator interacts with the acquisition and analysis components of the system by means of a user input device (24) with feedback on the graphics display (20).

Abstract translation: 一种从连接到患者头部（14）上的电极（13）获得（19）单极EEG信号的系统和方法。 EEG信号由电极检测并通过患者电缆（16）传输到EEG数据采集和分析系统（12）。 系统（12）生成所有功率谱，双谱和高阶光谱阵列。 然后将这些阵列与临床预定的系数阵列结合使用以产生诊断指标。 这些索引被发送到主计算机（18）并显示在图形显示器（2）上。 诊断索引的打印输出也可以连接到微型计算机（18）的硬拷贝输出装置（22）上。 操作者通过在图形显示器（20）上具有反馈的用户输入设备（24）与系统的采集和分析组件进行交互。

公开(公告)号：WO1998016152A2

公开(公告)日：1998-04-23

申请号：PCT/US1997018833

申请日：1997-10-10

Applicant: ASPECT MEDICAL SYSTEMS, INC.

Inventor： ASPECT MEDICAL SYSTEMS, INC. ,  DEVLIN, Philip, H. ,  CORDERO, Rafael, M. ,  CHAMOUN, Nassib, B. ,  SHAMBROOM, John, R. ,  FENDROCK, Charles ,  McDANIEL, Terrie, L.

IPC: A61B05/0408

CPC classification number: A61B5/04004 ,  A61B5/04085 ,  A61B5/0478 ,  A61B2560/045 ,  A61B2562/227

Abstract: An array of electrodes is constructed to allow the user to easily adjust to the correct size of the patient's head. The array is self-adhesive, pre-gelled and disposable. The array fits easily over the temple and forehead areas where EEG signals can be acquired by specially designed monitors for purposes of monitoring a number of bodily phenomena, including but not limited to, depth of anesthesia, and/or ischemia, and burst suppression. The array is connected to the monitor via a tab connector that is integral to the disposable device. The tab connector is insertible into a reusable connector that is part of a monitoring system.

Abstract translation: 电极阵列被构造成允许使用者容易地适应患者头部的正确尺寸。 阵列是自粘的，预胶凝的和一次性的。 该阵列容易地适合于通过专门设计的监视器用于监视许多身体现象（包括但不限于麻醉深度和/或局部缺血）和突发抑制的脑电图信号可以获得的神经元和前额区域。 阵列通过与一次性设备成一体的接头连接器连接到监视器。 标签连接器可插入作为监控系统一部分的可重复使用的连接器。

公开(公告)号：WO1994008507A1

公开(公告)日：1994-04-28

申请号：PCT/US1993009763

申请日：1993-10-13

Applicant: ASPECT MEDICAL SYSTEMS, INC.

Inventor： ASPECT MEDICAL SYSTEMS, INC. ,  SHAMBROOM, John, R.

IPC: A61B05/04

CPC classification number: A61B5/6843 ,  A61B5/0006 ,  A61B5/0476 ,  A61B5/7217 ,  G06F19/00 ,  G16H40/63 ,  Y10S128/901 ,  Y10S128/902

Abstract: An EEG monitor utilizes a portable acquisition module (14) and a substantially stationary processing module (12). The EEG signals are acquired and converted to an oversampled stream of digital signals by a sigma-delta modulator (64) located in the data acquisition module. The signals are then filtered by a decimation filter (62) located in the processing module. Additional means are also provided to monitor the electrode leads to detect when the leads become unplugged. The monitor provides all power to the data acquisition module over a single twisted line which transmits data as well.

Abstract translation: EEG监视器利用便携式采集模块（14）和基本上固定的处理模块（12）。 通过位于数据采集模块中的Σ-Δ调制器（64），获取EEG信号并将其转换为过采样的数字信号流。 然后通过位于处理模块中的抽取滤波器（62）对信号进行滤波。 还提供附加装置来监测电极引线以检测引线何时拔出。 显示器通过单个传输数据的双绞线向数据采集模块提供所有电源。

公开(公告)号：WO1994007409A1

公开(公告)日：1994-04-14

申请号：PCT/US1993009029

申请日：1993-09-23

Applicant: ASPECT MEDICAL SYSTEMS, INC.

Inventor： ASPECT MEDICAL SYSTEMS, INC. ,  FENDROCK, Charles

IPC: A61B05/0402

CPC classification number: A61B5/0408

Abstract: Disclosed is a disposable self-prepping electrode (10) which utilizes an array or mat of flexile tines (24) which serve to part the high impendance outer layers of skin to expose the low impendance, blood enriched layers without scratching or abrading. The tines (24) are preferably imbedded in a conductive gel layer (14). In an alternate embodiment, a self-prepping layer of flexile tines (24) embedded in gel (14) may be a single disposable self-prepping layer that is mounted over a permanent electrode (22).

Abstract translation: 公开了一种一次性自准备电极（10），其利用柔性尖头（24）的阵列或垫，其用于部分皮肤的高阻抗外层以暴露低阻抗的富血层而不会刮伤或磨损。 齿（24）优选地嵌入导电凝胶层（14）中。 在替代实施例中，嵌入在凝胶（14）中的柔性尖齿（24）的自准备层可以是安装在永久电极（22）上的单个一次性自准备层。

公开(公告)号：WO1997014358A1

公开(公告)日：1997-04-24

申请号：PCT/US1996016596

申请日：1996-10-18

Applicant: ASPECT MEDICAL SYSTEMS, INC.

Inventor： ASPECT MEDICAL SYSTEMS, INC. ,  DEVLIN, Philip, H. ,  CHAMOUN, Nassib, G. ,  SHAMBROOM, John, R. ,  BRUCKNER, Mark, E. ,  MARCUS, Todd, A.

IPC: A61B05/0428

CPC classification number: A61B18/14 ,  A61B5/0416 ,  A61B5/04286 ,  A61B5/0478 ,  A61B2018/00178 ,  A61B2560/045 ,  A61B2562/08 ,  A61B2562/227 ,  H01R29/00

Abstract: Disclosed is a physiological electrical signal connector system (20) with one connector (20a) connected to an electrode set (24) and another connector (20b) connected to a digital signal convertor (14) which leads to a patient monitor (10). Each type of electrode set has a specific code identified with it and when connected to the digital signal convertor (14), the connector code is recognized by the digital signal convertor. The connector code is then relayed to the monitor (10) which will self-configure based on the identified code.

Abstract translation: 公开了一种生理电信号连接器系统（20），其具有连接到电极组（24）的一个连接器（20a）和连接到通向患者监视器（10）的数字信号转换器（14）的另一个连接器（20b）。 每种类型的电极组具有用其识别的特定代码，并且当连接到数字信号转换器（14）时，连接器代码被数字信号转换器识别。 然后将连接器代码中继到监视器（10），监视器将根据识别的代码进行自配置。

公开(公告)号：WO1995033404A1

公开(公告)日：1995-12-14

申请号：PCT/US1995007310

申请日：1995-06-08

Applicant: ASPECT MEDICAL SYSTEMS, INC.

Inventor： ASPECT MEDICAL SYSTEMS, INC. ,  CHAMOUN, Nassib, G. ,  SIGL, Jeffrey, C. ,  SMITH, Charles, P.

IPC: A61B05/04

CPC classification number: A61B5/048 ,  A61B5/16 ,  A61B5/4821 ,  A61B5/725 ,  A61B5/7253 ,  A61B5/7257 ,  G06F19/00 ,  G16H15/00

Abstract: Disclosed is a system, comprising a microcomputer (18), a user input device (24), a graphics display (20), a hard copy output device (22), a method to derive a diagnostic index indicative of a selected cerebral phenomena which obtains (19) unipolar EEG signals in an acquisition, and an analysis system (12) from regions of interest on both the left and right hemispheres of the brain of a subject (15). The system uses high gain, low noise amplifiers to maximize the dynamic range for low energy wave components of the signals. Band-pass filtering is used to reduce noise and to avoid an alias. The system applies commonly used digital signal processing (DSP) techniques to digitize, to low pass filter (100Hz), and to decimate the signals. Power spectral, bi-spectral, and higher order spectral processing is then performed.

Abstract translation: 公开了一种系统，包括微型计算机（18），用户输入设备（24），图形显示器（20），硬拷贝输出设备（22），导出指示所选择的脑现象的诊断指标的方法， （19）在采集中获得（19）单极EEG信号，以及来自受试者的脑的左半球和右半球上的感兴趣区域的分析系统（12）。 该系统使用高增益低噪声放大器来最大化信号的低能量波分量的动态范围。 带通滤波用于降低噪声并避免别名。 该系统将常用的数字信号处理（DSP）技术应用于数字化，低通滤波器（100Hz），并对信号进行抽取。 然后执行功率谱，双光谱和高阶光谱处理。