公开(公告)号：WO2010142530A1

公开(公告)日：2010-12-16

申请号：PCT/EP2010/057258

申请日：2010-05-26

Applicant: UNIVERSITEIT TWENTE ,  STEENBERGEN, Wiendelt

Inventor： STEENBERGEN, Wiendelt

IPC: A61B5/00

CPC classification number: A61B5/415 ,  A61B5/0095 ,  A61B5/0097 ,  A61B5/418 ,  A61B5/4312 ,  A61B8/0825

Abstract: The invention relates to a method and a device, suitable for the measurement of quantitative photon absorption coefficient in tissue, wherein the device comprises a first light source, suitable for generating photons, a light measurement element suitable for measuring at least one of : the intensity, the frequency, the frequency deviations and phase shift of the light to be measured, an ultrasound source, suitable for the generation of a defined sound wave pattern in a defined volume element within the tissue, wherein the ultrasound source is suitable for labelling the light, originating from the first light source or a second light source that enters the defined volume element within the tissue, and an ultrasound measurement element, suitable for measuring ultrasound, originating from the defined volume element within the tissue and generated by the light of the first light source that enters the defined volume element within the tissue.

Abstract translation: 本发明涉及一种适于测量组织中定量光子吸收系数的方法和装置，其中该装置包括适于产生光子的第一光源，适用于测量以下至少之一的光测量元件：强度 ，要测量的光的频率，频率偏差和相移，适用于在组织内的限定的体积元件中产生限定的声波图案的超声源，其中超声源适于标记光 ，源自所述第一光源或进入所述组织内限定的体积元件的第二光源，以及适于测量超声波的超声测量元件，所述超声测量元件源自所述组织内限定的体积元件，并且由所述第一光源或所述第一光源 光源进入组织内限定的体积元素。

公开(公告)号：WO2010137974A1

公开(公告)日：2010-12-02

申请号：PCT/NL2010/050307

申请日：2010-05-21

Applicant: Universiteit Twente ,  KNOEF, Michel Henry ,  REIJERKERK, Sander Rogier ,  WESSLING, Matthias ,  NIJMEIJER, Dorothea Catharina

Inventor： KNOEF, Michel Henry ,  REIJERKERK, Sander Rogier ,  WESSLING, Matthias ,  NIJMEIJER, Dorothea Catharina

IPC: B01D71/80 ,  B01D71/70 ,  B01D71/52 ,  B01D71/56

CPC classification number: B01D71/80 ,  B01D61/007 ,  B01D71/52 ,  B01D71/56 ,  B01D71/70 ,  C08G77/46 ,  C08L51/085 ,  C08L53/00 ,  C08L75/04 ,  C08L2666/02 ,  C08L2666/24

Abstract: The present invention relates to a polymer composition comprising a blend of a multi-block thermoplastic elastomer comprising alternating hard polymeric blocks and soft polymeric blocks, and a polymer comprising a metal of Group 14 of the Periodic System of the Elements. The present invention also relates to a membrane comprising said blend and its application in separation processes, ion transport processes, ultrafiltration and nanofiltration.

Abstract translation: 本发明涉及一种聚合物组合物，其包含多嵌段热塑性弹性体的共混物，其包含交替的硬聚合物嵌段和软聚合物嵌段，以及包含元素周期系统的第14族金属的聚合物。 本发明还涉及包含所述共混物的膜及其在分离过程，离子传输方法，超滤和纳滤中的应用。

公开(公告)号：WO2005087239A1

公开(公告)日：2005-09-22

申请号：PCT/NL2005/000207

申请日：2005-03-18

Applicant: UNIVERSITEIT TWENTE ,  HENDRIKS, Jeanine, Anna, Alphonse ,  DE BRUIJN, Mark, Ewart ,  RIESLE, Jens, Uwe

Inventor： HENDRIKS, Jeanine, Anna, Alphonse ,  DE BRUIJN, Mark, Ewart ,  RIESLE, Jens, Uwe

IPC: A61K35/12

CPC classification number: C12N5/0602 ,  A61K35/28 ,  A61K35/32 ,  A61K35/33 ,  A61K35/34 ,  A61K35/545 ,  A61L27/3817 ,  A61L27/3834 ,  A61L27/3852 ,  A61L27/3886 ,  A61L27/3895 ,  B33Y70/00 ,  B33Y80/00 ,  C12N5/0655 ,  C12N2500/32 ,  C12N2502/1317 ,  C12N2506/1307 ,  C12N2533/30

Abstract: The invention relates to the field of medical science, in particular to technology directed at repairing defects in living, preferably human, tissue. The present invention provides a method for inducing differentiation of multipotent cells to a desired cell type, as well as a method for repairing a tissue defect in a human or animal patient using the concept of said method for inducing differentiation of multipotent cells. The invention further relates to a kit for carrying out the method for repairing a tissue defect.

Abstract translation: 本发明涉及医学领域，特别是涉及修复生物，优选人类组织中的缺陷的技术。 本发明提供一种诱导多能细胞分化成所需细胞类型的方法，以及使用所述诱导多潜能细胞分化方法的概念来修复人或动物患者组织缺陷的方法。 本发明还涉及一种用于执行修复组织缺陷的方法的试剂盒。

公开(公告)号：WO2003070807A1

公开(公告)日：2003-08-28

申请号：PCT/NL2003/000130

申请日：2003-02-20

Applicant: UNIVERSITEIT TWENTE ,  GAYMANS, Reinoud, Jaap ,  KRIJGSMAN, Josien ,  HUSKEN, Debby

Inventor： GAYMANS, Reinoud, Jaap ,  KRIJGSMAN, Josien ,  HUSKEN, Debby

IPC: C08G69/00

CPC classification number: C08G69/00 ,  C08G69/02 ,  C08G69/26 ,  C08G69/40 ,  C08G69/42

Abstract: Described herein are novel amide copolymers wherein the amide segments have a length of at least three amide groups of which its length is substantially uniform and which copolymers have a glass transition temperature of less than 0°C. A copolymer according to the invention displays a fast crystallization from the melt, and a modulus that is little dependant on the temperature in the temperature region between glass transition and melting temperature. A polymer according to the invention can easily be melt processed by extrusion, injection molding and fiber spinning. A copolymer according to the inventions may be transparent, has a high fracture strain and a high elasticity.

Abstract translation: 本文描述的是新型酰胺共聚物，其中酰胺链段具有至少三个酰胺基团的长度，其长度基本均匀，并且该共聚物的玻璃化转变温度低于0℃。 根据本发明的共聚物显示出来自熔体的快速结晶，以及几乎不依赖于玻璃化转变温度和熔融温度之间的温度区域的温度的模量。 根据本发明的聚合物可以容易地通过挤出，注射成型和纤维纺丝进行熔融加工。 根据本发明的共聚物可以是透明的，具有高的断裂应变和高的弹性。

公开(公告)号：WO1998027885A1

公开(公告)日：1998-07-02

申请号：PCT/NL1997000706

申请日：1997-12-17

Applicant: UNIVERSITEIT TWENTE ,  TECHNOLOGIESTICHTING STW ,  AALSMA, Arthur, Martinus, Michael ,  GROOTENBOER, Hendricus, Johannes ,  HEKMAN, Edsko, Evert, Geert ,  STAPERT, Jouwert, Wilhelm, Jacobus, Lucas

Inventor： UNIVERSITEIT TWENTE ,  TECHNOLOGIESTICHTING STW

IPC: A61B17/72

CPC classification number: A61B17/7216 ,  A61B17/7225 ,  A61B2017/00867

Abstract: A device for moving a first object relative to a second object, which device comprises a first part, which can be fixed to the first object, and a second part, which can be fixed to the second object. The first part comprises an elongated portion, along which the second part can move, which second part is provided with a clamping member, which is capable of clampingly engaging the elongated portion. The clamping member comprises shape memory metal, which gives the clamping member a clamping shape or a releasing (non-clamping) shape, depending on the temperature of the shape memory metal. The device may be suitable for being implanted into a human or animal body, whereby the first object is a first bone portion and the second object is a second bone portion, which bone portions are to be moved relative to each other.

Abstract translation: 一种用于相对于第二物体移动第一物体的装置，该装置包括可固定到第一物体的第一部分和可固定到第二物体的第二部分。 第一部分包括细长部分，第二部分可以沿该细长部分移动，该第二部分设置有夹紧构件，该夹紧构件能够夹紧地接合细长部分。 夹持构件包括形状记忆金属，其根据形状记忆金属的温度使夹持构件形成夹紧形状或释放（非夹紧）形状。 该装置可适于植入人体或动物体内，其中第一物体是第一骨骼部分，第二物体是第二骨骼部分，该骨骼部分将相对于彼此移动。

公开(公告)号：WO1996029031A1

公开(公告)日：1996-09-26

申请号：PCT/NL1996000125

申请日：1996-03-25

Applicant: UNIVERSITEIT TWENTE ,  GROOTENBOER, Hendricus, Johannes ,  HENDRIKS, Paul, Josephus, Hendrikus

Inventor： UNIVERSITEIT TWENTE

IPC: A61F02/64

CPC classification number: A61F2/644

Abstract: A leg prosthesis provided with a knee joint, which is on the one hand attached to an upper leg part and which is on the other hand attached to a lower leg part. The lower leg part can pivot with respect to said upper leg part, from an extended position to a flexed position. The knee joint is constructed in such a manner that the lower leg part and the upper leg part are initially moved away from each other when flexing from a substantially extended position. The knee joint may comprise four parallel pivot axes, whereby two lower leg pivot axes occupy a fixed position with respect to the first lower leg part and two upper leg pivot axes occupy a fixed position with respect to the upper leg part. Connecting elements pivotally connect each lower leg pivot axis to an upper leg pivot axis.

Abstract translation: 具有膝关节的腿假体，其一方面附接到大腿部，另一方面附接到小腿部。 小腿部分可以相对于所述上腿部分从延伸位置枢转到弯曲位置。 膝关节被构造成使得当从基本上伸出的位置弯曲时，小腿部分和大腿部部分最初彼此远离彼此移动。 膝关节可以包括四个平行的枢转轴线，由此两个小腿枢转轴线相对于第一小腿部分占据固定位置，并且两个大腿枢转轴线相对于大腿部部分占据固定位置。 连接元件将每个小腿枢转轴线枢转地连接到上腿枢轴。

公开(公告)号：WO2022154660A1

公开(公告)日：2022-07-21

申请号：PCT/NL2022/050010

申请日：2022-01-14

Applicant: UNIVERSITEIT TWENTE

Inventor： STEENBERGEN, Wiendelt ,  CHIZARI, Ata ,  KNOP, Tom

IPC: A61B5/00 ,  A61B5/026 ,  G01N21/00

Abstract: The invention relates to a handheld laser-based perfusion imaging apparatus comprising a light source and an imaging device which are arranged in a fixed orientation to each other in said apparatus. The light source is configured for projecting a beam of coherent light onto a measurement field at a predetermined distance spaced apart from the apparatus. The imaging device is configured for recording speckle intensity maps of the measurement field and/or images of Doppler shifted light of the measurement field. The light source is configured to provide a substantially spherical wavefront or a substantial planar wavefront, at least at the measurement field. Preferably, the apparatus with the light source that provides a substantial planar wavefront, comprises a gimbal mount. Furthermore, the invention relates to a method for measuring a perfusion in a tissue using the handheld laser-based perfusion imaging apparatus as described above.

公开(公告)号：WO2022128866A1

公开(公告)日：2022-06-23

申请号：PCT/EP2021/085396

申请日：2021-12-13

Applicant: UNIVERSITEIT TWENTE

Inventor： WANG, Huawei ,  SARTORI, Massimo

IPC: A61B5/11 ,  A61B5/103 ,  A61B5/00 ,  A43B5/00 ,  A61B5/22

Abstract: The invention provides a system (1) comprising a body wearable unit (1000), with one or more cameras (200), a control system (300), and an electrical power source (400). The invention further provides a method for generating wearer data using the system (1), wherein the method comprises monitoring with one or more cameras (200) a user wearing the wearable unit (1000) and providing a related camera signal; generating wearer data based on the related camera signal, wherein the wearer data comprise one or more of (i) wearer posture related data and (ii) wearer movement related data.

公开(公告)号：WO2021148528A1

公开(公告)日：2021-07-29

申请号：PCT/EP2021/051321

申请日：2021-01-21

Applicant: UNIVERSITEIT TWENTE

Inventor： WOUDA, Frank, Jasper ,  JASPAR, Stephan, Laurent, Jean, Odiel ,  VAN BEIJNUM, Bernhard, Johannes, Frederik ,  VELTINK, Petrus, Hermanus

IPC: A61B5/11 ,  A61B5/00 ,  A61B2562/0219 ,  A61B5/112 ,  A61B5/1121 ,  A61B5/6807 ,  A61B5/7242

Abstract: In a method and system for determining a foot progression angle of a foot, an inertial sensor is connected to the foot. The method comprises a processing system performing the steps of: acquiring, from the sensor, angular velocity data and acceleration data in a sensor coordinate system; identifying, based on said data, a first zero-velocity phase and a subsequent second zero-velocity phase; and during a step of the foot: mapping the angular velocity to a foot coordinate system; integrating the angular velocity to obtain an orientation of the foot direction; mapping the acceleration to the foot coordinate system; subtracting the acceleration of gravity from the acceleration to obtain a corrected acceleration; integrating the corrected acceleration to obtain a linear velocity; integrating the linear velocity to obtain a foot position; and determining the foot progression angle between the orientation of the foot at the first zero-velocity phase or the second zero-velocity phase, and a stepping direction of the foot.

公开(公告)号：WO2021118360A1

公开(公告)日：2021-06-17

申请号：PCT/NL2020/050785

申请日：2020-12-14

Applicant: UNIVERSITEIT TWENTE

Inventor： CHEN, Tao ,  VAN DER WIEL, Wilfred Gerard

IPC: H01L31/0224 ,  H01L31/0232 ,  H01L31/0352 ,  H01L31/09

Abstract: A photodetector is provided for sensing radiation in middle and long wave infrared domain. The sensor has a sensor layer of a first material having a first conductivity type and a first permittivity in which the shortest distance of any point in the sensor layer to an adjacent layer having a second conductivity type and a second permittivity lower than the first permittivity is 20 nanometres or less. Conductivity type may be semiconductor n-type or p-type or insulator. If, for example, a silicon sensor layer is sandwiched between two silicon oxide layers, the sensor layer of preferably p-type semiconductor has a maximum thickness of 40 nanometres. If a p-type layer of a first material is sandwiched between a dielectric layer with the second permittivity and an n-type layer of the first material, the maximum thickness is 20 nanometres. Spaced apart, two contacts are provided in contact with the sensor layer.