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公开(公告)号：JP2005500118A
公开(公告)日：2005-01-06
申请号：JP2003522372
申请日：2002-09-02
Inventor： アントニウス スハ―ル，ヨハネス , コルタ，クリストッフェル レーンダート デ , デル ステン，アントニウス フランシスカス ウィルヘルムス ファン , マスティック，フリッツ
CPC classification number: A61B8/485 , A61B8/0891 , A61B8/12
Abstract: A method for generating hardness information of tissue subject to a varying pressure. The method comprises receiving signals from the tissue from a sensor for measuring the deformation of the tissue in a measuring plane defined by the sensor, which sensor, during a varying pressure exerted on the tissue, is moved along the tissue in a direction transverse to the measuring plane; identifying strain of the tissue from the resulting signals; and relating the strain to elasticity and/or hardness parameters of the tissue. The method may comprise the step of displaying elasticity and/or hardness parameters of a tissue surface or tissue volume part extending practically parallel to the direction of motion of the sensor.
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公开(公告)号：US20040131634A1
公开(公告)日：2004-07-08
申请号：US10735098
申请日：2003-12-12
IPC: A61K039/02 , C07H021/04 , C12N001/21 , C07K014/22
CPC classification number: C07K14/22 , A61K39/00 , A61K2039/51
Abstract: LbpB polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing LbpB polypeptides and polynucleotides in the design of protocols for the treatment of neisserial disease, among others, and diagnostic assays for such conditions.
Abstract translation: 公开了通过重组技术制备这种多肽的LbpB多肽和多核苷酸和方法。 还公开了在设计用于治疗子宫颈疾病的方案中使用LbpB多肽和多核苷酸以及用于这些病症的诊断测定法的方法。
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公开(公告)号：WO2018130601A2
公开(公告)日：2018-07-19
申请号：PCT/EP2018/050629
申请日：2018-01-11
Applicant: STICHTING KATHOLIEKE UNIVERSITEIT , TECHNOLOGIESTICHTING STW NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK (NWO)
Inventor： MEIJS, Midas , MEIJER, Frederick J. Anton , MANNIESING, Rashindra
IPC: A61B6/00
Abstract: A system for extracting flow information from a dynamic volumetric angiography dataset is configured for segmenting (202) a vasculature structure by labeling certain voxels of the dynamic volumetric angiography dataset as belonging to the vasculature. For each of a plurality of the labeled voxels, (203) a voxel time value is calculated indicative of a time when a time sequence of a voxel of the dynamic volumetric angiography dataset satisfies a certain predetermined condition. A histogram is calculated (204) of the calculated voxel time values. The system determines (205) a time window having a lower voxel time value and an upper voxel time value, by fitting a model to the histogram, wherein the model defines the time window in terms of certain predetermined features of the histogram. The system associates (206) a first color to the lower voxel time value, and a second color to the upper voxel time value.
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公开(公告)号：WO2017135822A1
公开(公告)日：2017-08-10
申请号：PCT/NL2017/050069
申请日：2017-02-02
Applicant: TECHNISCHE UNIVERSITEIT DELFT , TECHNOLOGIESTICHTING STW
CPC classification number: B01D71/024 , B01D61/027 , B01D67/0072 , B01D2323/283 , B01D2323/42
Abstract: The present invention is in the field of a preparation of inorganic tight nanofiltration membranes with a cut-off
Abstract translation: 本发明属于无机紧间纳滤膜的制备领域，所述无机紧间纳滤膜具有使用原子层沉积的具有高渗透性<450Da的截止分子量，用所述方法获得的膜，以及 这种膜的应用。 无机膜（也称为陶瓷膜）用于水和废水处理，作为聚合物膜的替代品。 无机膜的优点是它们具有高机械强度，高耐化学性和耐热性，使用寿命长，并且可作为原料陶瓷材料回收利用。
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公开(公告)号：WO2005009125A1
公开(公告)日：2005-02-03
申请号：PCT/NL2004/000539
申请日：2004-07-27
Applicant: TECHNOLOGIESTICHTING STW , VAN DER PLAATS, Arjan , VERKERKE, Gijsbertus, Jacobus , RAKHORST, Gerhard , PLOEG, Rutger, Jan , 'T HART, Nils, Arnaud , LEUVENINK, Hendrik, Gerrit, Derk
Inventor： VAN DER PLAATS, Arjan , VERKERKE, Gijsbertus, Jacobus , RAKHORST, Gerhard , PLOEG, Rutger, Jan , 'T HART, Nils, Arnaud , LEUVENINK, Hendrik, Gerrit, Derk
IPC: A01N1/02
CPC classification number: A01N1/02 , A01N1/0247 , A01N1/0273
Abstract: A portable preservation apparatus of the cold storage type for a donor organ, comprising a cooling box provided with an organ chamber for receiving a donor organ in preservative fluid and a lid, wherein, on the side which operatively faces the organ chamber, the lid is provided with a connector which is detachably connected to the lid, which connector is provided with passages for one or more connecting pieces connected with the donor organ and one or more pipes connected with at least one perfusion pump, wherein the at least one perfusion pump is a miniature pump mounted at least partly in the lid and wherein the apparatus further comprises at least one oxygenator, an oxygen container, one or more electronic modules and a power supply module.
Abstract translation: 一种用于供体器官的冷藏型便携式保存装置，包括设置有用于接收防腐液体中的供体器官的器官腔的冷却箱和盖子，其中，在操作性地面向器官腔室的一侧，盖子是 设置有可拆卸地连接到盖的连接器，该连接器设置有用于与供体器官连接的一个或多个连接件的通道和与至少一个灌注泵连接的一个或多个管道，其中至少一个灌注泵是 至少部分地安装在所述盖中的微型泵，其中所述装置还包括至少一个氧合器，氧气容器，一个或多个电子模块和电源模块。
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Patent Agency Ranking
公开(公告)号：NL2011472C2
公开(公告)日：2015-03-23
申请号：NL2011472
申请日：2013-09-19
Applicant: UNIV DELFT TECH , TECHNOLOGIESTICHTING STW
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公开(公告)号：WO2010133347A3
公开(公告)日：2011-01-13
申请号：PCT/EP2010003049
申请日：2010-05-19
Applicant: UNIV LEIDEN , TECHNOLOGIESTICHTING STW , ZALM DIEDERIK JOHANNES VAN DER , HEERES ERWIN CORNELIS , HESSELBERTH MARINUS BERNARDUS STEPHANUS , KATAN ALLARD JULES , ES MAARTEN HUBERTUS VAN
Inventor： ZALM DIEDERIK JOHANNES VAN DER , HEERES ERWIN CORNELIS , HESSELBERTH MARINUS BERNARDUS STEPHANUS , KATAN ALLARD JULES , ES MAARTEN HUBERTUS VAN
CPC classification number: B25J7/00 , G02B21/26 , H01J37/20 , H01J37/28 , H01J2237/20221 , H01J2237/20264 , H01J2237/208 , H02N2/028
Abstract: A nano-scale manipulator (10) comprises a mounting deck (11) and a frame (12), the deck (11) being moveably secured to the frame (12) by two flexural joints permitting movement of the deck relative to the frame in first and second respective, mutually orthogonal directions of movement. Manipulator (10) also includes at least one respective, elongate piezoelectric actuator (21, 22) for each of the flexural joints, each respective piezoelectric actuator (21, 22) being secured so as to interconnect the deck (11) and the frame (12) and being extensible and contractible in a direction that is parallel to one of the said directions of movement; and a source (23) of electrical power for causing operation of each piezoelectric actuator (21, 22). Each of the piezoelectric actuators (21, 22) also is free to flex in directions other than its direction of extension and contraction.
Abstract translation: 纳米级操纵器（10）包括安装板（11）和框架（12），板（11）通过两个弯曲接头可移动地固定到框架（12），允许板相对于框架 第一和第二相应的相互正交的运动方向。 操纵器（10）还包括用于每个弯曲接头的至少一个相应的细长压电致动器（21,22），每个相应的压电致动器（21,22）被固定以便将平台（11）和框架 并且在与所述移动方向中的一个方向平行的方向上可伸长和收缩; 和用于使每个压电致动器（21,22）工作的电源（23）。 每个压电致动器（21,22）也在其伸缩方向以外的方向上自由弯曲。
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公开(公告)号：WO2010024664A8
公开(公告)日：2010-03-04
申请号：PCT/NL2009/000165
申请日：2009-08-26
Applicant: TECHNISCHE UNIVERSITEIT DELFT , TECHNOLOGIESTICHTING STW , VAN SCHIEVEEN, Jeroen, Paul , SPRONCK, Josephus, Wilhelmus
Abstract: The invention relates to an actuator for positioning an object in a first direction of movement, comprising a base, at least three positioning members, wherein each of the at least three positioning members has a contact surface which is configured to bear against the object under prestress, and a control device to drive the at least three positioning members in friction drive mode. In addition, the actuator comprises at least one heating device which is connected to the control device, in which the at least one heating device is configured to heat the at least three positioning members, and prestressing means to provide the prestress with which the contact surfaces of the at least three positioning members bear against the object, in which the at least three positioning members are of elongate design and are connected by one end to the base, and in which the contact surface is situated near the other end of the at least three positioning members, and in which the at least three positioning members are made from a material which expands under the effect of heat.
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公开(公告)号：WO2010024664A1
公开(公告)日：2010-03-04
申请号：PCT/NL2009000165
申请日：2009-08-26
Applicant: UNIV DELFT TECH , TECHNOLOGIESTICHTING STW , VAN SCHIEVEEN JEROEN PAUL , SPRONCK JOSEPHUS WILHELMUS
Inventor： VAN SCHIEVEEN JEROEN PAUL , SPRONCK JOSEPHUS WILHELMUS
CPC classification number: B81B3/0024 , B81B2201/047 , B81B2203/051
Abstract: The invention relates to an actuator for positioning an object in a first direction of movement, comprising a base, at least three positioning members, wherein each of the at least three positioning members has a contact surface which is configured to bear against the object under prestress, and a control device to drive the at least three positioning members in friction drive mode. In addition, the actuator comprises at least one heating device which is connected to the control device, in which the at least one heating device is configured to heat the at least three positioning members, and prestressing means to provide the prestress with which the contact surfaces of the at least three positioning members bear against the object, in which the at least three positioning members are of elongate design and are connected by one end to the base, and in which the contact surface is situated near the other end of the at least three positioning members, and in which the at least three positioning members are made from a material which expands under the effect of heat.
Abstract translation: 用于在第一运动方向上定位物体的致动器技术领域本发明涉及一种用于在第一运动方向上定位物体的致动器，该致动器包括基座，至少三个定位构件，其中，至少三个定位构件中的每一个具有接触表面，该接触表面构造成在预应力 以及以摩擦驱动模式驱动所述至少三个定位构件的控制装置。 此外，致动器包括至少一个加热装置，该加热装置连接到控制装置，其中至少一个加热装置构造成加热至少三个定位构件，以及预加应力装置提供预应力，该接触面 所述至少三个定位构件中的至少三个定位构件抵靠所述物体，其中所述至少三个定位构件具有细长设计并且通过一端连接到所述基部，并且其中所述接触表面位于所述至少三个定位构件的所述另一端附近 三个定位构件，并且其中所述至少三个定位构件由在热的作用下膨胀的材料制成。
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公开(公告)号：WO2007058527A3
公开(公告)日：2007-09-20
申请号：PCT/NL2006000575
申请日：2006-11-17
Applicant: AMC AMSTERDAM , TECHNOLOGIESTICHTING STW , BERKHOUT BENJAMIN , DAS ATZE TAEDE
Inventor： BERKHOUT BENJAMIN , DAS ATZE TAEDE
IPC: C12N15/63 , A61K48/00 , C07K14/245 , C12N7/01 , C12N15/10 , C12N15/867
CPC classification number: C12N7/00 , A61K39/12 , A61K39/21 , A61K2039/5254 , C12N15/635 , C12N2740/16034 , C12N2740/16061 , C12N2830/003
Abstract: The invention provides improved rtTA and single chain rtTA variants and uses thereof for inducible expression of a nucleic acid of interest. Nucleic acid sequences comprising an improved rtTA and/or sc rtTA sequence according to the invention are also provided, as well as vectors, replicons and cells comprising such nucleic acid sequences.
Abstract translation: 本发明提供改进的rtTA和单链rtTA变体及其用于诱导性表达感兴趣的核酸的用途。 还提供了包含根据本发明的改进的rtTA和/或sc rtTA序列的核酸序列，以及载体，复制子和包含该核酸序列的细胞。
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