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公开(公告)号：KR1020120058995A
公开(公告)日：2012-06-08
申请号：KR1020100120571
申请日：2010-11-30
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
CPC classification number: C12Q1/6809 , C12Q1/6883 , C12Q2600/158 , G01N33/5008
Abstract: PURPOSE: A method for screening a gene which characteristically developing aging is provided to control gene expression and to suppress aging on the skin. CONSTITUTION: A method for screening a gene associated with skin aging comprises: a step of extracting total RNA from skin tissue and performing microarray; a step of analyzing genes which are changed by aging using bioinformatics; a step of selecting a candidate gene relating to skin aging; and a step of determining a candidate gene. The skin aging includes intrinsic aging or menopause aging.
Abstract translation: 目的：提供筛选特征性发展老化基因的方法，以控制基因表达并抑制皮肤老化。 构成：筛选与皮肤老化有关的基因的方法包括：从皮肤组织提取总RNA并进行微阵列的步骤; 分析使用生物信息学老化改变的基因的步骤; 选择与皮肤老化有关的候选基因的步骤; 以及确定候选基因的步骤。 皮肤老化包括内在老化或更年期老化。
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公开(公告)号：KR1020120058863A
公开(公告)日：2012-06-08
申请号：KR1020100120370
申请日：2010-11-30
Applicant: (주)아모레퍼시픽
CPC classification number: G01N33/573 , G01N2333/96466 , G01N2800/20 , A61Q19/004 , A61Q19/007 , C12Q1/68 , C12Q1/686 , C12Q2600/148 , C12Q2600/158
Abstract: PURPOSE: A method for screening a material for treating dry skin is provided to prevent skin moisturizing and to recover skin barrier. CONSTITUTION: A method for screening a material for treating dry skin comprises a step of screening candidate materials based on expression change of bleomycin hydolase(BH) gene. The gene expression level is measured by PCR. An external use skin composition contains LXR activator which enhances BH gene expression level as an active ingredient. The composition is used for treating dry skin or moisturizing skin.
Abstract translation: 目的：提供一种筛选用于治疗干性皮肤的材料的方法，以防止皮肤保湿并恢复皮肤屏障。 构成：筛选用于治疗干性皮肤的材料的方法包括基于博来霉素水解酶（BH）基因的表达变化筛选候选物质的步骤。 通过PCR测定基因表达水平。 外用皮肤组合物含有增强BH基因表达水平作为活性成分的LXR活化剂。 该组合物用于治疗干性皮肤或保湿皮肤。
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125.发明公开세콰이어 캘러스 추출물을 함유하는 지방유래 줄기세포의 줄기세포성 증진용 및 피부세포 증식용 조성물 有权用于促进ADIPOSE衍生的干细胞的STEMNESS的化妆品组合物和含有SEQUYIA CALLUS细胞提取物的增殖皮肤细胞
公开(公告)号：KR1020120058829A
公开(公告)日：2012-06-08
申请号：KR1020100120313
申请日：2010-11-30
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/14 , A61K8/00 , A61K8/0216 , A61K8/0225 , A61K8/06 , A61K8/97 , A61K8/981 , A61K35/00 , A61K35/12 , A61K35/28 , A61K35/545 , A61K36/00 , A61K36/13 , A61M35/00 , A61Q19/00
Abstract: PURPOSE: A composition containing Sequoia callus extract is provided to promote regeneration of adipose-derived stem cells and to recover damaged subcutaneous fat. CONSTITUTION: A composition for enhancing the stemness of adipose-derived stem cells(hADSCs) contains Sequoia callus extract as an active ingredient. The composition enhances CD29 and CD44 expression level. A composition for enhancing skin cell proliferation contains the extract as an active ingredient. The skin cell is transit-amplifying cells(TA cells). The composition contains 0.0001-10 wt% of the extract. A skin care method comprises a step of treating the composition on the skin.
Abstract translation: 目的：提供含有红杉愈伤组织提取物的组合物，以促进脂肪来源的干细胞的再生并恢复损伤的皮下脂肪。 构成：用于增强脂肪干细胞（hADSC）的干性的组合物含有红杉愈伤组织提取物作为活性成分。 该组合物增强CD29和CD44表达水平。 用于增强皮肤细胞增殖的组合物含有提取物作为活性成分。 皮肤细胞是转运扩增细胞（TA细胞）。 组合物含有0.0001-10重量％的提取物。 护肤方法包括在皮肤上处理组合物的步骤。
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Patent Agency Ranking
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公开(公告)号：KR101082272B1
公开(公告)日：2011-11-09
申请号：KR1020090015228
申请日：2009-02-24
Applicant: (주)아모레퍼시픽
Abstract: 본발명은식물의새싹추출물을함유한조성물에관한것으로, 세쿼이어새싹, 빌베리새싹, 복숭아새싹, 발아배추, 발아브로콜리, 발아해바라기및 발아케일로부터추출한새싹추출물을유효성분으로포함하고있다. 상기조성물은피부세포의증식을촉진하고, 피부줄기세포의생존과증식을증진시킴으로써, 피부노화를지연및 개선하는효능이뛰어나다.
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公开(公告)号：KR1020110013147A
公开(公告)日：2011-02-09
申请号：KR1020090108203
申请日：2009-11-10
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A cosmetic composition containing polymersomes in which peptides or hydrolysed millets are encapsulated is provided to improve whiteninig, elasticity, anti-wrinkling, skin transparency and moisturizing without skin irritation. CONSTITUTION: A cosmetic composition contains polymersomes in which peptides or hydrolyzed millets are encapsulated, as an active ingredient. The polymersome is prepared by synthesizing polylactic acid and polyethylene glycol in a weight ration of 1:1-1:10. The peptide encapsulated in the polymersomes is diaminopropionoyl tripeptide-33, palmitoyl tripeptide-5, palmitoyl pentapeptide-4, acetyl heptapeptie-4, copper tripeptide-1, lysine polypeptide or acetyl tetrapeptide-11. The cosmetic composition is used for skin moisturizing, anti-wrinkling, skin transparency and anti-aging.
Abstract translation: 目的：提供一种包含聚合物囊泡的化妆品组合物，其中肽或水解的密丝被包封，以提高白化度，弹性，抗皱纹，皮肤透明度和保湿，而无皮肤刺激。 构成：化妆品组合物含有聚合物囊泡，其中肽或水解的细丝被包封，作为活性成分。 通过以1：1-1：10的重量比合成聚乳酸和聚乙二醇制备聚合物。 封装在聚合物囊中的肽是二氨基丙酰基三肽-33，棕榈酰三肽-5，棕榈酰五肽-4，乙酰基七肽-4，铜三肽-1，赖氨酸多肽或乙酰四肽-11。 化妆品组合物用于皮肤保湿，抗皱，皮肤透明和抗老化。
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公开(公告)号：KR1020100023372A
公开(公告)日：2010-03-04
申请号：KR1020080082094
申请日：2008-08-21
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A cosmetic composition containing Phyllanthus urinaria extract as an active ingredient is provided to promote collagen synthesis and to suppress MMP-1(Matrix metalloproteinase-1) and cyclooxygenase-2 synthesis. CONSTITUTION: A cosmetic composition for anti-aging, anti-oxidation, and anti-wrinkle contains 0.001-10 weight% of Phyllanthus urinaria extract as an active ingredient. The extract is obtained using ethanol, methanol, butanol, ether, etheracetate, or chloroform. The cosmetic composition is used in the form of skin softener, astringent, nutrition lotion, nutrition cream, massage cream, essence, eye cream, eye essence, cleansing cream, cleansing foam, cleansing water, pack, powder, body lotion, body cream, body oil or body essence.
Abstract translation: 目的：提供含有叶黄叶提取物作为活性成分的化妆品组合物，以促进胶原合成和抑制MMP-1（基质金属蛋白酶-1）和环氧合酶-2的合成。 构成：用于抗衰老，抗氧化和抗皱的化妆品组合物含有0.001-10重量％的作为活性成分的珍珠提取物。 提取物用乙醇，甲醇，丁醇，乙醚，乙醚酸乙酯或氯仿得到。 化妆品组合物以皮肤柔软剂，收敛剂，营养乳液，营养霜，按摩霜，精华液，眼霜，眼睛精华，清洁霜，清洁泡沫，清洁水，包装，粉末，身体乳液，身体霜， 身体油或身体精华。
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公开(公告)号：KR1020100021755A
公开(公告)日：2010-02-26
申请号：KR1020080080346
申请日：2008-08-18
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A cosmetic composition for improving anti-aging is provided to remove free radical or protect intracellular anti-oxidation. CONSTITUTION: An anti-aging cosmetic composition contains 0.01-90 weight% of blueberry, raspberry, and punica granatum L. extract. A method for extracting blueberry, raspberry, and punica granatum L. comprises: a step of adding the blueberry, raspberry, and punica granatum L. in flask; and a step of immersing with 2L of butylenes glycol for three days and filtering remove residue. The cosmetic composition is used in the form of emulsion, cream, lotion, essence, pack, gel, powder, lipstick, makeup base, foundation, or lotion.
Abstract translation: 目的：提供用于改善抗衰老的化妆品组合物，以去除自由基或保护细胞内的抗氧化。 构成：抗衰老化妆品组合物含有0.01-90重量％的蓝莓，覆盆子和竹atum提取物。 一种提取蓝莓，覆盆子和白花椒的方法，包括：将蓝莓，覆盆子和白花椒L.在烧瓶中加入的步骤; 以及用2L丁二醇浸渍三天并过滤除去残留物的步骤。 化妆品组合物以乳剂，霜剂，洗剂，香精，包装，凝胶，粉末，口红，化妆底，粉底或洗剂的形式使用。
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