Methods of making pyrrolidones
    123.
    发明公开
    Methods of making pyrrolidones 审中-公开
    Verfahren zur Pyrrolidon-Herstellung

    公开(公告)号:EP2210877A1

    公开(公告)日:2010-07-28

    申请号:EP10004429.6

    申请日:2002-06-17

    CPC classification number: C07D207/267 C07D201/02 C07D201/08

    Abstract: The present invention provides methods for making N-methylpyrrolidine and analogous compounds via hydrogenation. Novel catalysts for this process, and novel conditions/yields are also described. Other process improvements may include extraction and hydrolysis steps. Some preferred reactions take place in the aqueous phase. Starting materials for making N-methylpyrrolidine may include succinic acid, N-methylsuccinimide, and their analogs.

    Abstract translation: 本发明提供通过氢化制备N-甲基吡咯烷和类似化合物的方法。 还描述了用于该方法的新型催化剂和新的条件/收率。 其他工艺改进可以包括提取和水解步骤。 一些优选的反应发生在水相中。 用于制备N-甲基吡咯烷的原料可包括琥珀酸,N-甲基琥珀酰亚胺及其类似物。

    PROCESSES FOR PRODUCING EPSILON CAPROLACTAMS
    127.
    发明公开
    PROCESSES FOR PRODUCING EPSILON CAPROLACTAMS 失效
    用于生产己内酰胺EPSILON

    公开(公告)号:EP0975591A1

    公开(公告)日:2000-02-02

    申请号:EP98914690.7

    申请日:1998-04-14

    Abstract: This invention relates in part to processes for producing one or more substituted or unsubstituted epsilon caprolactams, e.g., epsilon caprolactam, which comprises: (a) subjecting one or more substituted or unsubstituted alkadienes to hydroxycarbonylation in the presence of a hydroxycarbonylation catalyst, e.g., a metal-organophosphorus ligand complex catalyst, and neutralization with a base to produce one or more substituted or unsubstituted pentenoic acid salts; (b) subjecting said one or more substituted or unsubstituted pentenoic acid salts to hydroformylation in the presence of a hydroformylation catalyst, e.g., a metal-organophosphorus ligand complex catalyst, to produce one or more substituted or unsubstituted formylvaleric acid salts and/or one or more substituted or unsubstituted epsilon caprolactam precursors; and (c) subjecting said one or more substituted or unsubstituted formylvaleric acid salts and/or said one or more substituted or unsubstituted epsilon caprolactam precursors to reductive amination in the presence of a reductive amination catalyst and cyclization optionally in the presence of a cyclization catalyst to produce said one or more substituted or unsubstituted epsilon caprolactams. This invention also relates in part to reaction mixtures containing one or more substituted or unsubstituted epsilon caprolactams as the principal product(s) of reaction.

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