中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

157 records (took 0.018 seconds)

    Vertical beam spectrophotometer
    121.
    发明公开
    Vertical beam spectrophotometer 失效
    Spektralphotometer mit senkrechtemBündel。

    公开(公告)号：EP0283802A2

    公开(公告)日：1988-09-28

    申请号：EP88103398.9

    申请日：1988-03-04

    Applicant: ABBOTT LABORATORIES

    Inventor： Houseman, Kenneth Russell ,  Wender, David C. ,  Banovez, Lawrence George ,  Wroblewski, Mieczyslaw

    IPC: G01N21/59 ,  G01N21/47 ,  G01N33/53 ,  G01N33/543

    CPC classification number: G01N21/253 ,  G01J2003/123 ,  G01N2201/0407 ,  G01N2201/0826 ,  Y10S436/807

    Abstract: A vertical beam spectrophotometer for measur­ing the light absorption of an assay prepared using standard wet chemistry procedures and conventional solid phase coated bead technology is disclosed. The spectrophotometer measures the absorption of the assay in a conventional reaction cuvette with the bead remain­ing in the cuvette. The light source of the spectro­photometer illuminates the bead, which diffuses the light into the surrounding assay solution. A lense projects the diffused light onto a photocell which con­verts it into an electrical signal having magnitude related to the light absorption of the assay. The signal is processed in a known manner by conventional processing circuitry to obtain an absorption value.

    Abstract translation: 公开了一种垂直光束分光光度计，用于测量使用标准湿化学方法和常规固相涂布珠粒技术制备的分析物的光吸收。 分光光度计测量在常规反应试管中的吸附，其中珠子保留在比色杯中。 分光光度计的光源照射珠，将光扩散到周围的测定溶液中。 透镜将漫射光投射到光电管上，该光电管将其转换成具有与测定的光吸收相关的幅度的电信号。 以常规处理电路以已知的方式处理该信号以获得吸收值。

    RESONANT CAVITY PHOTODIODE ARRAY FOR RAPID DNA MICROARRAY READOUT
    123.
    发明申请
    RESONANT CAVITY PHOTODIODE ARRAY FOR RAPID DNA MICROARRAY READOUT 审中-公开
    用于快速DNA微阵列的共振光谱光栅阵列

    公开(公告)号：WO2004051241A3

    公开(公告)日：2004-09-10

    申请号：PCT/US0337571

    申请日：2003-11-24

    Applicant: SPIRE CORP

    Inventor： LITTLE ROGER G ,  LINDEN KURT J

    IPC: G01N21/64 ,  G01N21/77

    CPC classification number: G01N21/6454 ,  G01N2021/6469 ,  G01N2201/0407 ,  G01N2201/0612

    Abstract: The present invention provides a microarray having a plurality of micro-locations for confining selected photophores, for example, biological molecules exhibiting fluorescence spectra. The microarray can further include an array of optoelectronic photodetectors each of which is optically coupled with at least one of the micro-locations to detect radiation, for example, fluorescence radiation, that is emitted from the photophores confined in that micro-location. Each photodetector includes a resonant cavity that is formed of a front reflector and/or a back reflector having distributed Bragg reflector structures and a photo-detecting element disposed in the resonant cavity. The microarray can utilize either external optical excitation sources, such as lasers, LEDs, or can contain its own excitation sources in an integrated structure containing both optical radiation emitters, such as, vertical cavity surface emitting lasers or resonant cavity LEDs, and resonant cavity photodetectors. The integrated emitters and detectors can be either coaxially or adjacently located. Further, the microarray can include either separate sample array and excitation/detector array plates, or a single sample/excitation/detector array plate in which the photophore-containing sample molecules can be deposited directly on the excitation/detector array.

    Abstract translation: 本发明提供一种微阵列，其具有用于限制所选择的光致抗体的多个微位置，例如表现出荧光光谱的生物分子。 微阵列还可以包括光电子检测器阵列，每个光电检测器与至少一个微位置光学耦合，以检测从限制在该微位置的光电子发射的辐射，例如荧光辐射。 每个光电检测器包括谐振腔，其由具有分布式布拉格反射器结构的前反射器和/或后反射器形成，以及设置在谐振腔中的光检测元件。 微阵列可以利用诸如激光器，LED的外部光学激发源，或者可以在包含光辐射发射器（诸如垂直腔表面发射激光器或谐振腔LED）的集成结构中包含其自身的激发源，以及谐振腔光电探测器 。 集成的发射器和检测器可以同轴或相邻地定位。 此外，微阵列可以包括单独的样品阵列和激发/检测器阵列板，或者单个样品/激发/检测器阵列板，其中含光致抗体的样品分子可以直接沉积在激发/检测器阵列上。

    RESONANT CAVITY PHOTODIODE ARRAY FOR RAPID DNA MICROARRAY READOUT
    124.
    发明申请
    RESONANT CAVITY PHOTODIODE ARRAY FOR RAPID DNA MICROARRAY READOUT 审中-公开
    用于快速DNA微阵列读数的共振腔光电二极管阵列

    公开(公告)号：WO2004051241A2

    公开(公告)日：2004-06-17

    申请号：PCT/US2003/037571

    申请日：2003-11-24

    Applicant: SPIRE CORPORATION

    Inventor： LITTLE, Roger, G. ,  LINDEN, Kurt, J.

    IPC: G01N21/64

    CPC classification number: G01N21/6454 ,  G01N2021/6469 ,  G01N2201/0407 ,  G01N2201/0612

    Abstract: The present invention provides a microarray having a plurality of micro-locations for confining selected photophores, for example, biological molecules exhibiting fluorescence spectra. The microarray can further include an array of optoelectronic photodetectors each of which is optically coupled with at least one of the micro-locations to detect radiation, for example, fluorescence radiation, that is emitted from the photophores confined in that micro-location. Each photodetector includes a resonant cavity that is formed of a front reflector and/or a back reflector having distributed Bragg reflector structures and a photo-detecting element disposed in the resonant cavity. The microarray can utilize either external optical excitation sources, such as lasers, LEDs, or can contain its own excitation sources in an integrated structure containing both optical radiation emitters, such as, vertical cavity surface emitting lasers or resonant cavity LEDs, and resonant cavity photodetectors. The integrated emitters and detectors can be either coaxially or adjacently located. Further, the microarray can include either separate sample array and excitation/detector array plates, or a single sample/excitation/detector array plate in which the photophore-containing sample molecules can be deposited directly on the excitation/detector array.

    Abstract translation: 本发明提供了一种微阵列，其具有用于限制选择的发光团的多个微位置，例如显示荧光光谱的生物分子。 微阵列可以进一步包括光电子光电检测器阵列，每个光电子光电检测器与至少一个微位置光耦合以检测从被限制在该微位置的光电子发射的辐射，例如荧光辐射。 每个光电检测器包括由具有分布式布拉格反射器结构的前反射器和/或后反射器和设置在谐振腔中的光检测元件形成的谐振腔。 微阵列可以利用诸如激光器，LED之类的外部光激发源，或者可以在包含光辐射发射器（诸如垂直腔表面发射激光器或谐振腔LED）和谐振腔光电探测器两者的集成结构中包含其自己的激发源 。 集成的发射器和探测器可以同轴或相邻定位。 此外，微阵列可以包括单独的样品阵列和激发/检测器阵列板，或者单个样品/激发/检测器阵列板，其中含有发光团的样品分子可以直接沉积在激发/检测器阵列上。

    SPECIMEN PROCESSING AND ANALYZING SYSTEMS AND METHODS USING PHOTOMETRY
    126.
    发明申请
    SPECIMEN PROCESSING AND ANALYZING SYSTEMS AND METHODS USING PHOTOMETRY 审中-公开
    样本处理和分析系统和使用光度法的方法

    公开(公告)号：WO1993009440A1

    公开(公告)日：1993-05-13

    申请号：PCT/US1992009097

    申请日：1992-10-27

    Applicant: BAXTER DIAGNOSTICS INC.

    Inventor： BAXTER DIAGNOSTICS INC. ,  GRINER, Christopher, D.

    IPC: G01N35/02

    CPC classification number: G01N21/253 ,  G01N21/274 ,  G01N35/028 ,  G01N2201/0407 ,  G01N2201/0446 ,  G01N2201/08 ,  G01N2201/1283

    Abstract: A system (10) uses a photometer that establishes an optical channel between a light emitter (102) and a light detector (106). The photometer analyzes a specimen while it occupies a well (48) in a tray (12). A movable platform (74) transports the tray (12) to the optical channel for analysis and removes the tray (12) from the optical channel after analysis. The system calibrates the movable platform (74) to assure proper alignment between the specimen and the photometric apparatus used to analyze the specimen. The system also calibrates the optical channel without use of an external reference.

    Abstract translation: 系统（10）使用在光发射器（102）和光检测器（106）之间建立光通道的光度计。 光度计在托盘（12）中占据井（48）时对样本进行分析。 可移动平台（74）将托盘（12）运送到光学通道用于分析，并在分析之后从光学通道中移除托盘（12）。 系统校准可移动平台（74），以确保样品与用于分析样品的测光设备之间的正确对准。 该系统还可以校准光通道而不使用外部参考。

    SAMPLE HANDLING SYSTEM FOR AN OPTICAL MONITORING SYSTEM
    127.
    发明申请
    SAMPLE HANDLING SYSTEM FOR AN OPTICAL MONITORING SYSTEM 审中-公开
    一种光学监测系统的样品处理系统

    公开(公告)号：WO1991008464A1

    公开(公告)日：1991-06-13

    申请号：PCT/US1990006992

    申请日：1990-11-30

    Applicant: AKZO N.V. ,  HULETTE, William, Chester, Jr. ,  KARP, Joseph, George ,  CALLAHAN, Janet, Black ,  BRAUN, Paul, Joseph ,  RICHARDSON, Stephen

    Inventor： AKZO N.V.

    IPC: G01N21/11

    CPC classification number: G01N35/00732 ,  G01N35/026 ,  G01N35/1004 ,  G01N35/1072 ,  G01N35/1079 ,  G01N2035/00376 ,  G01N2035/00435 ,  G01N2035/00752 ,  G01N2035/0403 ,  G01N2035/0487 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2201/0407

    Abstract: A sample handling system for an optical evaluation instrument. A cuvette storage mechanism (10) is provided for storing a plurality of cuvettes (50), each of which has a plurality of reaction wells. A temperature controlled housing (26) is provided for storing a plurality of reagent containers each containing a respective reagent, and a plurality of sample collection tubes, containing a fluid sample and each presenting an optically scannable code identifying the sample and a test to be performed on the sample. A programming station (30) is provided for optically reading the code (32) presented by the respective sample collection tubes for programming the instrument with a test to be performed. A sample insertion station (14) includes a mechanism (36) for aspirating a portion of the sample from a sample collection tube and for dispensing the aspirated sample portion into a reaction well of a cuvette. A first transporter (28) transports the sample collection tubes first to the programming station (30) and then to the sample insertion station (14). A second transporter (12) transports the cuvettes through the sample insertion station (14) and the reagent station (16, 18 and 20) and onto the monitoring means (22).

    Abstract translation: 光学评估仪器的样品处理系统。 提供比色皿存储机构（10），用于存储多个反应杯（50），每个比色皿具有多个反应孔。 提供温度控制的外壳（26），用于存储每个含有各自试剂的多个试剂容器和多个样本收集管，其中包含流体样品，并且每个样本收集管都具有识别样品的可光学扫描的代码和待执行的测试 在样品上。 提供了一个编程站（30），用于光学读取由相应的采样管呈现的代码（32），用于对要进行测试的仪器进行编程。 样品插入台（14）包括用于从样品收集管吸取样品的一部分并将抽吸的样品部分分配到反应杯的反应槽中的机构（36）。 第一运送器（28）将样品收集管首先运送到编程站（30），然后运送到样品插入站（14）。 第二转运器（12）通过样品插入站（14）和试剂站（16,18和20）运送比色杯并运送到监测装置（22）上。

Patent Agency Ranking