公开(公告)号：ZA201100046B

公开(公告)日：2011-10-26

申请号：ZA201100046

申请日：2011-01-03

Applicant: CODA THERAPEUTICS INC

Inventor： DUFT BRADFORD J ,  GREEN COLIN

IPC: A61P20060101 ,  C12N15/113

Abstract: The present invention relates to delivery, including transdermal delivery, of a therapeutically effective amount of a compound useful for modulating gap junction formation and function, including an oligonucleotide for reducing gap junction formation and function, and methods and compositions for treating a subject suffering from pain associated with a disease, disorder or condition and associated with pain, including but not limited to muscle pain, ligament pain, tendon pain, joint pain and post-operative pain.

公开(公告)号：ZA201005223B

公开(公告)日：2011-09-28

申请号：ZA201005223

申请日：2010-07-21

Applicant: CODA THERAPEUTICS INC

Inventor： BECKER DAVID L ,  GREEN COLIN R ,  DUFT BRADFORD J

IPC: A61K20060101 ,  A61L20060101 ,  A61P20060101 ,  C12N15/113

Abstract: Methods, compounds, compositions, kits and articles of manufacture comprising anti-connexin polynucleotides for prevention and/or treatment of abnormal scars, including keloid scars, hypertrophic scars, atrophic scars, and widespread scars.

公开(公告)号：ZA201005215B

公开(公告)日：2011-06-29

申请号：ZA201005215

申请日：2010-07-21

Applicant: CODA THERAPEUTICS INC

Inventor： DUFT BRADFORD J

IPC: C12N15/113

Abstract: Compositions, articles, devices and methods for the treatment and/or prevention of adhesions in humans and non-human animals.

公开(公告)号：HK1136213A1

公开(公告)日：2010-06-25

申请号：HK10103066

申请日：2010-03-23

Applicant: CODA THERAPEUTICS INC

Inventor： BECKER DAVID L ,  GREEN COLIN R ,  DUFT BRADFORD J

IPC: A61K20060101 ,  A61P20060101 ,  C12N15/113

Abstract: Connexin modulation for the treatment of wounds that do not heal at expected rates, including delayed healing wounds, incompletely healing wounds, and chronic wounds, and associated methods, compositions and articles.

公开(公告)号：CA2710388A1

公开(公告)日：2009-07-09

申请号：CA2710388

申请日：2008-12-22

Applicant: CODA THERAPEUTICS INC

Inventor： BECKER DAVID L ,  GREEN COLIN R ,  DUFT BRADFORD J

IPC: A61K48/00 ,  A61K31/7088 ,  A61P17/02 ,  A61P27/02 ,  A61P43/00 ,  C12N15/113 ,  C12Q1/00

Abstract: Methods, compounds, compositions, kits and articles of manufacture comprising anti- connexin polynucleotides for prevention and/or treatment of abnormal scars, including keloid scars, hypertrophic scars, atrophic scars, and widespread scars.

公开(公告)号：CA2710382A1

公开(公告)日：2009-07-09

申请号：CA2710382

申请日：2008-12-22

Applicant: CODA THERAPEUTICS INC

Inventor： DUFT BRADFORD J

IPC: A61K48/00 ,  A61K38/17 ,  A61P41/00 ,  C12N15/113

Abstract: Methods, compounds, compositions, kits and articles of manufacture comprising anti-connexin agents for treatment of orthopedic disorders, diseases, or conditions, and improving recoveries and outcomes of orthopedic procedures or surgeries.

公开(公告)号：CA2710375A1

公开(公告)日：2009-07-09

申请号：CA2710375

申请日：2008-12-22

Applicant: CODA THERAPEUTICS INC

Inventor： BECKER DAVID L ,  GREEN COLIN R ,  DUFT BRADFORD J

IPC: A61K48/00 ,  A61K38/17 ,  A61K39/395 ,  A61P41/00 ,  C12N15/113

Abstract: Methods, compounds, compositions, kits and articles of manufacture comprising anti- connexin agents for treatment of orthopedic disorder, disease, or condition, and promoting post-surgical wound-healing.

公开(公告)号：AU2008343839A1

公开(公告)日：2009-07-09

申请号：AU2008343839

申请日：2008-12-22

Applicant: CODA THERAPEUTICS INC

Inventor： DUFT BRADFORD J

IPC: A61K38/17 ,  A61K9/70 ,  A61K48/00 ,  A61L24/00 ,  A61P41/00 ,  C12N15/113

Abstract: Compositions, articles, devices and methods for the treatment and/or prevention of adhesions in humans and non-human animals.

公开(公告)号：EA029094B9

公开(公告)日：2018-04-30

申请号：EA201100953

申请日：2004-12-03

Applicant: CODA THERAPEUTICS INC

Inventor： LAUX WILDA ,  GREEN COLIN R

IPC: C12N15/11 ,  A61K31/7088 ,  A61P25/00 ,  A61P27/02 ,  C12N15/113

Abstract: Визобретениипредставленыспособыи композициидлямодуляцииактивностейконнексинов, втомчисле, например, дляпримененияв постхирургическихприменениях, примененияхпритравмеилипримененияхдляконструированияткани. Этисоединенияи способымогутбытьиспользованытерапевтически, напримердляуменьшениятяжестисвязанныхс побочнымиэффектамизаболеванийи нарушений, прикоторыхявляетсяжелательнымлокализованноеразрушениепрямойкоммуникацииклетка-клетка.

公开(公告)号：IL244085A

公开(公告)日：2018-02-28

申请号：IL24408516

申请日：2016-02-11

Applicant: CODA THERAPEUTICS INC ,  CODA THERAPEUTICS NZ LTD

IPC: C12N15/113

Abstract: Methods and compositions for modulating the activities of connexins are provided, including, for example, for use in post-surgical, trauma, or tissue engineering applications. These compounds and methods can be used therapeutically, for example, to reduce the severity of adverse effects associated diseases and disorders where localized disruption in direct cell-cell communication is desirable.