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公开(公告)号:US20100178222A1
公开(公告)日:2010-07-15
申请号:US12664621
申请日:2008-06-13
Applicant: Kiyoshi Nokihara , Yasuo Oka
Inventor: Kiyoshi Nokihara , Yasuo Oka
IPC: B01J19/00
CPC classification number: B01J19/0093 , B01J2219/00783 , B01J2219/00819 , B01J2219/00831 , B01J2219/0086 , B01J2219/00873 , B01L3/502707 , B01L2200/0689 , B01L2300/0883 , B01L2300/12 , B81B2201/051 , B81B2201/058 , B81B2203/0307 , B81C3/001 , B81C2203/0109 , B81C2203/032
Abstract: Means for overcoming the problems which the conventional glass microchannel chips have are disclosed. That is, a microchannel chip in which microchannels can be formed at a low cost, and which has a high chemical resistance is disclosed. The microchannel chip is constituted by a substrate made of carbon, which has a channel in its surface; and a cover composed of a glass plate bonded to the substrate. The cover is bonded to the substrate by heating at least a part of the contact surface at which the substrate is in contact with the cover.
Abstract translation: 公开了克服传统玻璃微通道芯片所存在的问题的手段。 也就是说,公开了一种微通道芯片,其中可以以低成本形成微通道,并且具有高耐化学性。 微通道芯片由碳表面构成,其表面具有通道; 以及由与基板结合的玻璃板构成的盖。 通过加热基板与盖接触的接触表面的至少一部分,将盖结合到基板。
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132.
公开(公告)号:US07703313B2
公开(公告)日:2010-04-27
申请号:US11675043
申请日:2007-02-14
Applicant: Robert E. Higashi
Inventor: Robert E. Higashi
IPC: G01N25/00
CPC classification number: B81B3/0081 , B01L3/5027 , B01L3/502707 , B01L2200/14 , B01L2300/0627 , B01L2300/0816 , B01L2300/1827 , B81B2201/051 , B81B2201/058 , G01N30/6095 , G01N2030/025
Abstract: Embodiments of the invention relate to a fluid containment structure for a micro analyzer comprising one or more shelled thermal structures in contact with a thermally isolated component of the analyzer and wherein the shelled thermal structure comprises a conformal film and also comprises three walls of a channel and the thermally isolated component forms the fourth wall.
Abstract translation: 本发明的实施例涉及一种用于微分析器的流体容纳结构,其包括与分析仪的热隔离部件接触的一个或多个外壳热结构,并且其中所述带壳热结构包括保形膜,并且还包括三个通道壁和 热隔离部件形成第四壁。
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公开(公告)号:US20100074815A1
公开(公告)日:2010-03-25
申请号:US12447392
申请日:2007-10-19
Applicant: Kanji Sekihara , Masayoshi Uehira
Inventor: Kanji Sekihara , Masayoshi Uehira
CPC classification number: B29C33/42 , B29C33/3878 , B81B2201/051 , B81C99/0085
Abstract: Mold releasability of a molding die from a master is improved. The master is a mother body of the molding die. The master has a groove corresponding to a flow channel of a resin molded product, and the cross-section of the bottom surface portion of the groove is in the form of a curved surface.
Abstract translation: 提高了模具从母模的脱模性。 主人是模具的母体。 主机具有对应于树脂模制产品的流动通道的凹槽,并且凹槽的底表面部分的横截面为曲面形式。
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134.
公开(公告)号:US20100071418A1
公开(公告)日:2010-03-25
申请号:US12526900
申请日:2008-02-27
Applicant: Thierry Luc Alain Dannoux , Paulo Gaspar Jorge Marques , Robert Michael Morena , Cameron Wayne Tanner
Inventor: Thierry Luc Alain Dannoux , Paulo Gaspar Jorge Marques , Robert Michael Morena , Cameron Wayne Tanner
IPC: C03B17/00
CPC classification number: C03B11/084 , B81B2201/051 , B81C99/0085 , B81C2201/019 , B81C2201/036 , C03B2215/07
Abstract: Methods for molding glass and glass composites, including providing a first structure having a first surface, providing a second structure having a second surface, the second surface being patterned and porous, and disposing between the first and second surfaces an amount of a composition comprising a glass, then heating together the first and second structures and the first amount of the composition sufficiently to soften the first amount of the composition such that the first and second structures, under gravity or an otherwise applied force, move toward each other, such that the pattern of the second surface is formed into the first amount of the composition, then cooling the composition sufficiently to stabilize it, the second structure comprising porous carbon having an open porosity of at least 5% and wherein the amount of the composition is removable from the second surface, without damage to the amount of the composition or to the second surface, such that the second surface is in condition for re-use.
Abstract translation: 用于模制玻璃和玻璃复合材料的方法,包括提供具有第一表面的第一结构,提供具有第二表面的第二结构,第二表面被图案化和多孔化,并且在第一表面和第二表面之间设置一定量的组合物, 玻璃,然后将第一和第二结构和第一量的组合物充分加热以软化第一量的组合物,使得第一和第二结构在重力或以其他方式施加的力下朝向彼此移动,使得 将第二表面的图案形成为第一量的组合物,然后充分冷却组合物以使其稳定,第二结构包括具有至少5%的开放孔隙率的多孔碳,并且其中组合物的量可从 第二表面,而不损害组合物的量或第二表面,使得第二表面是 在重新使用的条件下。
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135.
公开(公告)号:US20090281250A1
公开(公告)日:2009-11-12
申请号:US12063284
申请日:2006-08-09
Applicant: Joseph M. DeSimone , Jason P. Rolland , Ginger M. Dennison Rothrock , Paul Resnick
Inventor: Joseph M. DeSimone , Jason P. Rolland , Ginger M. Dennison Rothrock , Paul Resnick
IPC: C08L67/00 , C08G18/71 , B05D3/00 , C08F2/48 , B44C1/22 , B29C33/40 , G03F7/00 , F15C3/00 , F15C5/00 , G05D7/00
CPC classification number: B29C59/005 , B01L3/502707 , B01L2300/0887 , B01L2300/12 , B29C33/3878 , B29C33/405 , B29C65/48 , B29C65/4835 , B29C65/4845 , B29C65/485 , B29C65/521 , B29C66/54 , B29C66/543 , B29C66/71 , B29C66/723 , B29C66/727 , B29C66/91431 , B29C66/919 , B29C66/949 , B29C66/9534 , B29K2883/00 , B29L2031/756 , B81B2201/051 , B81C99/0085 , C08G18/10 , C08G18/5015 , C08G18/8175 , C08G59/30 , C08G65/007 , C08L71/02 , C08L75/16 , Y10T137/0318 , Y10T137/2224 , C08G18/50 , B29C65/00 , B29K2027/18 , B29K2027/12
Abstract: Materials and Methods are provided for fabricating microfluidic devices. The materials include low surface energy fluoropolymer compositions having multiple cure functional groups. The materials can include multiple photocurable and/or thermal-curable functional groups such that laminate devices can be fabricated. The materials also substantially do not swell in the presence of hydrocarbon solvents.
Abstract translation: 提供材料和方法用于制造微流体装置。 这些材料包括具有多个固化官能团的低表面能含氟聚合物组合物。 这些材料可以包括多个可光固化和/或热固化的官能团,使得可以制造层压装置。 所述材料在烃溶剂存在下也基本上不溶胀。
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公开(公告)号:US20090274586A1
公开(公告)日:2009-11-05
申请号:US12502394
申请日:2009-07-14
Applicant: Hiroshi KAWAZOE , Akishi NAKASO , Shigeharu ARIKE
Inventor: Hiroshi KAWAZOE , Akishi NAKASO , Shigeharu ARIKE
IPC: B01L3/00
CPC classification number: B01L3/502707 , B01J19/0093 , B01J2219/00783 , B01J2219/00788 , B01J2219/00822 , B01J2219/00833 , B01J2219/0086 , B01J2219/00869 , B01L2200/12 , B01L2300/0816 , B01L2300/0838 , B01L2300/0874 , B01L2300/0887 , B01L2400/0481 , B01L2400/0655 , B81B2201/051 , B81C1/00119 , B81C2201/019 , B81C2203/032 , Y10T156/10
Abstract: A support unit for a microfluidic system includes a first support; a first adhesive layer provided on a surface of the first support; and a hollow filament laid on a surface of the first adhesive layer to have an arbitrary shape and functioning as a flow channel layer of the microfluidic system.
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公开(公告)号:US20090269245A1
公开(公告)日:2009-10-29
申请号:US12496212
申请日:2009-07-01
Applicant: Hiroshi KAWAZOE , Akishi NAKASO , Shigeharu ARIKE
Inventor: Hiroshi KAWAZOE , Akishi NAKASO , Shigeharu ARIKE
CPC classification number: B01L3/502707 , B01J19/0093 , B01J2219/00783 , B01J2219/00788 , B01J2219/00822 , B01J2219/00833 , B01J2219/0086 , B01J2219/00869 , B01L2200/12 , B01L2300/0816 , B01L2300/0838 , B01L2300/0874 , B01L2300/0887 , B01L2400/0481 , B01L2400/0655 , B81B2201/051 , B81C1/00119 , B81C2201/019 , B81C2203/032 , Y10T156/10
Abstract: A support unit for a microfluidic system includes a first support; a first adhesive layer provided on a surface of the first support; and a hollow filament laid on a surface of the first adhesive layer to have an arbitrary shape and functioning as a flow channel layer of the microfluidic system.
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公开(公告)号:US20090064790A1
公开(公告)日:2009-03-12
申请号:US12087394
申请日:2006-12-22
Applicant: Jerome Vivien Davidovits , James Scott Sutherland
Inventor: Jerome Vivien Davidovits , James Scott Sutherland
CPC classification number: B01J19/0093 , B01J2219/00783 , B01J2219/00824 , B01J2219/00831 , B01J2219/00853 , B01J2219/0086 , B01J2219/00907 , B01J2219/00963 , B01J2219/0097 , B81B7/02 , B81B2201/0264 , B81B2201/051 , B81B2203/0127 , B81C2201/019 , C03C17/04 , C03C2218/328 , C03C2218/33
Abstract: Microfluidic devices having wall structures comprised of sintered glass frit and further including a glass, glass-ceramic or ceramic membrane structure sealed by a sintered seal to said wall structures, such that a fluid passage or chamber is defined at least in part by the wall structures and said membrane structure. This allows for changes in pressure within the fluid passage or chamber to cause deflections of the membrane structure, providing for direct measurement of pressure within the device. The microfluidic device may have both floors and walls of sintered frit, or may have only walls of sintered frit, with planar floor-like substrate structures, thicker than the membrane structure defining the vertical boundaries of the internal passages. The device may include multiple fluid passages or chambers each defined at least in part by a membrane structure. Multiple membrane structures may be used in a single device, and one single membrane structure may be used for multiple passages or chamber.
Abstract translation: 具有由烧结玻璃料组成的壁结构并且还包括通过烧结密封件密封到所述壁结构的玻璃,玻璃陶瓷或陶瓷膜结构的微流体装置,使得流体通道或室至少部分地由壁结构限定 和膜结构。 这允许流体通道或腔室内的压力变化导致膜结构的偏转,从而直接测量装置内的压力。 微流体装置可以具有烧结玻璃料的两个底板和壁,或者可以仅具有烧结玻璃料的壁,其具有平面地板状衬底结构,比限定内部通道的垂直边界的膜结构更厚。 该装置可以包括多个流体通道或室,每个液体通道至少部分地由膜结构限定。 多个膜结构可以用于单个装置中,并且一个单一的膜结构可用于多个通道或室。
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公开(公告)号:US07479186B2
公开(公告)日:2009-01-20
申请号:US11415672
申请日:2006-05-01
Applicant: Stephen R. Quake , Carl L. Hansen , James M. Berger
Inventor: Stephen R. Quake , Carl L. Hansen , James M. Berger
IPC: C30B29/54
CPC classification number: C30B29/00 , B01D9/00 , B01D9/0072 , B01D9/0077 , B01J19/0046 , B01J2219/00274 , B01J2219/00286 , B01J2219/00317 , B01J2219/00389 , B01J2219/00418 , B01J2219/00432 , B01J2219/00585 , B01J2219/00756 , B01J2219/00891 , B01J2219/00907 , B01J2219/00952 , B01L3/06 , B01L3/5025 , B01L3/50273 , B01L3/502738 , B01L3/502753 , B01L7/54 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0605 , B01L2200/10 , B01L2300/0681 , B01L2300/0816 , B01L2300/0861 , B01L2300/123 , B01L2300/14 , B01L2300/18 , B01L2400/0481 , B01L2400/0655 , B01L2400/0688 , B81B2201/051 , B81B2201/054 , B81B2203/0127 , B81B2203/0315 , B81C1/00119 , B81C99/0065 , C30B7/14 , C30B29/54 , C30B29/58 , F04B43/043 , F16K99/0001 , F16K99/0015 , F16K99/0046 , F16K99/0051 , F16K99/0059 , F16K2099/0074 , F16K2099/0078 , F16K2099/008 , Y10T117/10 , Y10T117/1004 , Y10T117/1008 , Y10T117/1024
Abstract: High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated fluidic device. The microfabricated fluidic device is then manipulated to vary the solution condition in the chambers, thereby simultaneously providing a large number of crystallization environments. Control over changed solution conditions may result from a variety of techniques, including but not limited to metering volumes of crystallizing agent into the chamber by volume exclusion, by entrapment of volumes of crystallizing agent determined by the dimensions of the microfabricated structure, or by cross-channel injection of sample and crystallizing agent into an array of junctions defined by intersecting orthogonal flow channels.
Abstract translation: 目标材料的结晶化的高通量筛选是通过将目标材料的溶液同时引入微细加工的流体装置的多个室来实现的。 然后对微制造的流体装置进行操作以改变室中的溶液状态,从而同时提供大量的结晶环境。 改变的溶液条件的控制可以由各种技术产生,包括但不限于通过体积排阻将结晶剂计量到室中的体积,通过捕获通过微结构结构的尺寸确定的结晶剂的体积, 将样品和结晶剂通道注入由相交的正交流动通道限定的连接阵列。
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公开(公告)号:US20070169686A1
公开(公告)日:2007-07-26
申请号:US11689302
申请日:2007-03-21
Applicant: Stephen Quake , Carl Hansen , James Berger
Inventor: Stephen Quake , Carl Hansen , James Berger
CPC classification number: C30B29/00 , B01D9/00 , B01D9/0072 , B01D9/0077 , B01J19/0046 , B01J2219/00274 , B01J2219/00286 , B01J2219/00317 , B01J2219/00389 , B01J2219/00418 , B01J2219/00432 , B01J2219/00585 , B01J2219/00756 , B01J2219/00891 , B01J2219/00907 , B01J2219/00952 , B01L3/06 , B01L3/5025 , B01L3/50273 , B01L3/502738 , B01L3/502753 , B01L7/54 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0605 , B01L2200/10 , B01L2300/0681 , B01L2300/0816 , B01L2300/0861 , B01L2300/123 , B01L2300/14 , B01L2300/18 , B01L2400/0481 , B01L2400/0655 , B01L2400/0688 , B81B2201/051 , B81B2201/054 , B81B2203/0127 , B81B2203/0315 , B81C1/00119 , B81C99/0065 , C30B7/14 , C30B29/54 , C30B29/58 , F04B43/043 , F16K99/0001 , F16K99/0015 , F16K99/0046 , F16K99/0051 , F16K99/0059 , F16K2099/0074 , F16K2099/0078 , F16K2099/008 , Y10T117/10 , Y10T117/1004 , Y10T117/1008 , Y10T117/1024
Abstract: High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated fluidic device. The microfabricated fluidic device is then manipulated to vary the solution condition in the chambers, thereby simultaneously providing a large number of crystallization environments. Control over changed solution conditions may result from a variety of techniques, including but not limited to metering volumes of crystallizing agent into the chamber by volume exclusion, by entrapment of volumes of crystallizing agent determined by the dimensions of the microfabricated structure, or by cross-channel injection of sample and crystallizing agent into an array of junctions defined by intersecting orthogonal flow channels.
Abstract translation: 目标材料的结晶化的高通量筛选是通过将目标材料的溶液同时引入微细加工的流体装置的多个室来实现的。 然后对微制造的流体装置进行操作以改变室中的溶液状态,从而同时提供大量的结晶环境。 改变的溶液条件的控制可以由各种技术产生,包括但不限于通过体积排阻将结晶剂计量到室中的体积,通过捕获通过微结构结构的尺寸确定的结晶剂的体积, 将样品和结晶剂通道注入由相交的正交流动通道限定的连接阵列。
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