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公开(公告)号：US11733160B2
公开(公告)日：2023-08-22
申请号：US17666238
申请日：2022-02-07
Applicant: SomaDetect Inc.
Inventor： Bethany Deshpande , Nicholas Clermont , Satish Deshpande , Bharath Sudarsan , Bryan Wattie
CPC classification number: G01N21/51 , A61D99/00 , G01N2021/4707 , G01N2201/1296
Abstract: Methods and systems for detecting the presence of irregularities in milk, and for assessing a health state of a lactating mammal, are provided. A sample of milk is illuminated with a light beam. Scattering data resulting from an interaction between the light beam and the sample of milk is collected. The scattering data is processed to detect the presence or absence of light scattered at a predetermined angle relative to a normal orientation, for instance to determine at least one characteristic of the sample of milk. Based on the presence or absence of light, the presence of irregularities in the sample of milk can be determined, for instance to assess the health state of the lactating mammal based on the at least one characteristic of the sample of milk.
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公开(公告)号：US11650348B2
公开(公告)日：2023-05-16
申请号：US16860183
申请日：2020-04-28
Applicant: Halliburton Energy Services, Inc.
Inventor： David Perkins , Dingding Chen , Christopher Michael Jones , Jing Shen
CPC classification number: G01V8/10 , G01N21/31 , G01N2201/1296
Abstract: A model can be trained for discriminant analysis for substance classification and/or measuring calibration. One method includes interacting at least one sensor with one or more known substances, each sensor element being configured to detect a characteristic of the one or more known substances, generating an sensor response from each sensor element corresponding to each known substance, wherein each known substance corresponds to a known response stored in a database, and training a neural network to provide a discriminant analysis classification model for an unknown substance, the neural network using each sensor response as inputs and one or more substance types as outputs, and the outputs corresponding to the one or more known substances.
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公开(公告)号：US10082600B2
公开(公告)日：2018-09-25
申请号：US14364119
申请日：2011-12-16
Applicant: Jing Shen , Christopher Jones , Dingding Chen , Michael T. Pelletier , Robert Atkinson , David Perkins
Inventor： Jing Shen , Christopher Jones , Dingding Chen , Michael T. Pelletier , Robert Atkinson , David Perkins
CPC classification number: G01V13/00 , G01N21/274 , G01N33/241 , G01N2201/129 , G01N2201/1296
Abstract: A method of calibration transfer for a testing instrument includes: collecting a first sample; generating a standard response of a first instrument based, at least in part, on the first sample; and performing instrument standardization of a second instrument based, at least in part, on the standard response of the first instrument. Data corresponding to a second sample is then obtained using the second instrument and a component of the second sample is identified based, at least in part, on a calibration model.
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公开(公告)号：US10067051B2
公开(公告)日：2018-09-04
申请号：US14606812
申请日：2015-01-27
Applicant: CIRECA THERANOSTICS, LLC , NORTHEASTERN UNIVERSITY
Inventor： Max Diem , Benjamin Bird , Milos Miljkovic , Stanley H. Remiszewski , Clay M. Thompson
IPC: G01N33/48 , G01N33/50 , G01N21/31 , A61B5/00 , G01N21/552 , G01N21/64 , G01N21/65 , G06K9/00 , G06F19/00 , G06T7/30 , G01N21/3581 , G01N21/35 , G06K9/46
CPC classification number: G01N21/31 , A61B5/0071 , A61B5/0075 , A61B5/415 , A61B5/418 , A61B5/7257 , G01N21/35 , G01N21/3581 , G01N21/552 , G01N21/6456 , G01N21/65 , G01N2021/3595 , G01N2021/6417 , G01N2021/653 , G01N2201/1293 , G01N2201/1296 , G06K9/00134 , G06K9/00147 , G06K2009/4657 , G06T7/30 , G06T2207/20101 , G06T2207/30024 , G16H50/20
Abstract: A method for analyzing biological specimens by spectral imaging to provide a medical diagnosis includes obtaining spectral and visual images of biological specimens and registering the images to detect cell abnormalities, pre-cancerous cells, and cancerous cells. This method eliminates the bias and unreliability of diagnoses that is inherent in standard histopathological and other spectral methods. In addition, a method for correcting confounding spectral contributions that are frequently observed in microscopically acquired infrared spectra of cells and tissue includes performing a phase correction on the spectral data. This phase correction method may be used to correct various types of absorption spectra that are contaminated by reflective components.
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公开(公告)号：US09726012B2
公开(公告)日：2017-08-08
申请号：US14240611
申请日：2013-03-08
Applicant: Halliburton Energy Services, Inc.
Inventor： Dingding Chen , David Perkins , Jing Cynthia Shen , Christopher Michael Jones
CPC classification number: E21B49/08 , G01N21/274 , G01N21/31 , G01N21/3577 , G01N21/84 , G01N33/2823 , G01N2201/1296
Abstract: Systems and methods for optical fluid identification approximation and calibration are described herein. One example method includes populating a database with a calculated pseudo optical sensor (CPOS) response of a first optical tool to a first sample fluid. The CPOS response of the first optical tool may be based on a transmittance spectrum of a sample fluid and may comprise a complex calculation using selected components of the first optical tool. A first model may be generated based, at least in part, on the database. The first model may receive as an input an optical sensor response and output a predicted fluid property. A second model may also be generated based, at least in part, on the database. The second model may receive as an input at least one known/measured fluid/environmental property value and may output a predicted pseudo optical sensor response of the first optical tool.
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Patent Agency Ranking
146.发明授权公开(公告)号：US09546949B2
公开(公告)日：2017-01-17
申请号：US14408725
申请日：2013-12-20
Applicant: Halliburton Energy Services, Inc.
Inventor： Neal G. Skinner
IPC: G01N21/55 , G01N21/31 , G01N21/27 , G01J3/00 , G01N21/25 , G01J3/28 , G01J3/32 , G01N21/552 , G01J3/12
CPC classification number: G01N21/31 , G01J3/00 , G01J3/2803 , G01J3/32 , G01J2003/1226 , G01N21/255 , G01N21/27 , G01N21/314 , G01N21/552 , G01N2201/06113 , G01N2201/062 , G01N2201/12 , G01N2201/1296 , G02B5/285
Abstract: Optical computing devices including a light source that emits electromagnetic radiation into an optical train extending from the light source to a detector, a substance arranged in the optical train and configured to optically interact with the electromagnetic radiation and produce sample interacted radiation, a processor array arranged in the optical train and including a plurality of ICE arranged on a substrate and configured to optically interact with the electromagnetic radiation. The detector receives modified electromagnetic radiation generated through optical interaction of the electromagnetic radiation with the substance and the processor array. A weighting device is coupled to one or more of the ICE to optically apply a weighting factor to the modified electromagnetic radiation prior to being received by the detector, wherein the detector generates an output signal indicative of a characteristic of the substance based on beams of modified electromagnetic radiation.
Abstract translation: 光学计算设备，包括将电磁辐射发射到从光源延伸到检测器的光学系列中的光源，布置在光学系列中并被配置为与电磁辐射光学相互作用并产生样品相互作用的辐射的物质，布置成 并且包括布置在基板上并被配置为与电磁辐射光学相互作用的多个ICE。 检测器接收通过电磁辐射与物质和处理器阵列的光学相互作用产生的修改的电磁辐射。 加权装置耦合到ICE中的一个或多个，以在由检测器接收之前将加权因子光学地应用于修改的电磁辐射，其中，所述检测器基于经修改的光束来生成指示所述物质的特征的输出信号 电磁辐射。
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公开(公告)号：US20160084767A1
公开(公告)日：2016-03-24
申请号：US14954365
申请日：2015-11-30
Applicant: PD-LD, Inc.
Inventor： Boris Leonidovich Volodin , Vladimir Sinisa Ban
IPC: G01N21/65
CPC classification number: G01J3/0256 , G01J3/00 , G01J3/10 , G01J3/1895 , G01J3/44 , G01J3/4412 , G01J2003/104 , G01N21/65 , G01N21/658 , G01N2021/1793 , G01N2201/0221 , G01N2201/129 , G01N2201/1296 , G02B6/29319 , H01S5/005 , H01S5/32 , H01S5/4012 , H01S5/4087
Abstract: Apparatus for performing Raman spectroscopy may include a first laser source having a first emission wavelength and a second laser source having a second emission wavelength. A separation between the first and second emission wavelengths may correspond to a width of a Raman band of a substance of interest. A switch may provide switching between the first and second laser sources. An ensemble of laser emitters may be provided. A Bragg grating element may receive laser light from the ensemble. An optical system may direct light from the Bragg grating element into an optical fiber. A combined beam through the optical fiber may contain light from each of the emitters.
Abstract translation: 用于执行拉曼光谱的装置可以包括具有第一发射波长的第一激光源和具有第二发射波长的第二激光源。 第一和第二发射波长之间的间隔可以对应于感兴趣物质的拉曼带的宽度。 开关可以提供第一和第二激光源之间的切换。 可以提供激光发射器的组合。 布拉格光栅元件可以接收来自集合体的激光。 光学系统可以将来自布拉格光栅元件的光引导到光纤中。 通过光纤的组合光束可以包含来自每个发射器的光。
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公开(公告)号：US20150142333A1
公开(公告)日：2015-05-21
申请号：US14606812
申请日：2015-01-27
Applicant: CIRECA THERANOSTICS, LLC , NORTHEASTERN UNIVERSITY
Inventor： Max DIEM , Benjamin BIRD , Milos MILJKOVIC , Stanley H. REMISZEWSKI , Clay M. THOMPSON
CPC classification number: G01N21/31 , A61B5/0071 , A61B5/0075 , A61B5/415 , A61B5/418 , A61B5/7257 , G01N21/35 , G01N21/3581 , G01N21/552 , G01N21/6456 , G01N21/65 , G01N2021/3595 , G01N2021/6417 , G01N2021/653 , G01N2201/1293 , G01N2201/1296 , G06F19/00 , G06K9/00134 , G06K9/00147 , G06K2009/4657 , G06T7/30 , G06T2207/20101 , G06T2207/30024 , G16H50/20
Abstract: A method for analyzing biological specimens by spectral imaging to provide a medical diagnosis includes obtaining spectral and visual images of biological specimens and registering the images to detect cell abnormalities, pre-cancerous cells, and cancerous cells. This method eliminates the bias and unreliability of diagnoses that is inherent in standard histopathological and other spectral methods. In addition, a method for correcting confounding spectral contributions that are frequently observed in microscopically acquired infrared spectra of cells and tissue includes performing a phase correction on the spectral data. This phase correction method may be used to correct various types of absorption spectra that are contaminated by reflective components.
Abstract translation: 通过光谱成像分析生物标本以提供医学诊断的方法包括获得生物标本的光谱和视觉图像并登记图像以检测细胞异常，癌前细胞和癌细胞。 该方法消除了标准组织病理学和其他光谱方法固有的诊断的偏倚和不可靠性。 此外，用于校正在细胞和组织的显微取得的红外光谱中经常观察到的混杂光谱贡献的方法包括对光谱数据执行相位校正。 该相位校正方法可用于校正被反射组件污染的各种类型的吸收光谱。
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149.发明授权Methods for monitoring fluids within or produced from a subterranean formation during fracturing operations using opticoanalytical devices 有权在使用光学分析装置的压裂操作期间监测地下地层内或由地下地层产生的流体的方法公开(公告)号：US08960294B2
公开(公告)日：2015-02-24
申请号：US13204123
申请日：2011-08-05
Applicant: Robert P. Freese , Christopher M. Jones , Michael T. Pelletier , Rory D. Daussin , David M. Loveless , Johanna Haggstrom
Inventor： Robert P. Freese , Christopher M. Jones , Michael T. Pelletier , Rory D. Daussin , David M. Loveless , Johanna Haggstrom
CPC classification number: G01N21/85 , C09K8/62 , E21B43/26 , E21B43/28 , E21B2049/085 , G01N2201/1296
Abstract: In or near real-time monitoring of fluids can take place using an opticoanalytical device that is configured for monitoring the fluid. Fluids can be monitored prior to or during their introduction into a subterranean formation using the opticoanalytical devices. Produced fluids from a subterranean formation can be monitored in a like manner. The methods can comprise providing a fracturing fluid comprising a base fluid and at least one fracturing fluid component; introducing the fracturing fluid into a subterranean formation at a pressure sufficient to create or enhance at least one fracture therein, thereby performing a fracturing operation in the subterranean formation; and monitoring a characteristic of the fracturing fluid or a formation fluid using at least a first opticoanalytical device within the subterranean formation, during a flow back of the fracturing fluid produced from the subterranean formation, or both.
Abstract translation: 使用配置用于监测流体的光学分析装置可以在或接近实时监测流体。 可以使用光学分析装置在将其引入地下地层之前或期间监测流体。 可以以类似的方式监测来自地下地层的液体。 该方法可以包括提供包括基础流体和至少一个压裂流体组分的压裂流体; 将压裂流体以足以产生或增强其中的至少一个裂缝的压力引入地下地层，从而在地层中进行压裂作业; 以及在从地下地层产生的压裂流体的回流期间或两者中，使用至少第一光学分析装置在地下地层内监测压裂液或地层流体的特性。
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公开(公告)号：US20140125977A1
公开(公告)日：2014-05-08
申请号：US14149321
申请日：2014-01-07
Applicant: PD-LD, Inc.
Inventor： Boris Leonidovich Volodin , Vladimir Sinisa Ban
CPC classification number: G01J3/0256 , G01J3/00 , G01J3/10 , G01J3/1895 , G01J3/44 , G01J3/4412 , G01J2003/104 , G01N21/65 , G01N21/658 , G01N2021/1793 , G01N2201/0221 , G01N2201/129 , G01N2201/1296 , G02B6/29319 , H01S5/005 , H01S5/32 , H01S5/4012 , H01S5/4087
Abstract: Apparatus for performing Raman spectroscopy may include a first laser source having a first emission wavelength and a second laser source having a second emission wavelength. A separation between the first and second emission wavelengths may correspond to a width of a Raman band of a substance of interest. A switch may provide switching between the first and second laser sources. An ensemble of individually addressable laser emitters may be provided. A Bragg grating element may receive laser light from the ensemble. An optical system may direct light from the Bragg grating element into an optical fiber. A combined beam through the optical fiber may contain light from each of the emitters.
Abstract translation: 用于执行拉曼光谱的装置可以包括具有第一发射波长的第一激光源和具有第二发射波长的第二激光源。 第一和第二发射波长之间的间隔可以对应于感兴趣物质的拉曼带的宽度。 开关可以提供第一和第二激光源之间的切换。 可以提供可单独寻址的激光发射器的组合。 布拉格光栅元件可以接收来自集合体的激光。 光学系统可以将来自布拉格光栅元件的光引导到光纤中。 通过光纤的组合光束可以包含来自每个发射器的光。
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