公开(公告)号：WO2014205256A2

公开(公告)日：2014-12-24

申请号：PCT/US2014043245

申请日：2014-06-19

Applicant: GEN HOSPITAL CORP

Inventor： NADKARNI SEEMANTINI K ,  WANG JING

IPC: A61B1/313 ,  A61B1/00

CPC classification number: A61B5/0084 ,  A61B5/0062 ,  A61B5/02007 ,  A61B5/02028 ,  A61B5/6853 ,  A61B5/6869 ,  A61B5/6876 ,  A61B5/7203 ,  A61B5/7275 ,  G01N21/474 ,  G01N21/4788 ,  G01N21/49 ,  G01N2021/4742 ,  G01N2021/479 ,  G01N2201/0683 ,  G01N2201/08 ,  G01N2201/0826 ,  G02B6/0005 ,  G02B23/2453 ,  G02B23/26

Abstract: An apparatus for obtaining information regarding a biological structure(s) can include, for example a light guiding arrangement which can include a fiber through which an electromagnetic radiation(s) can be propagated, where the electromagnetic radiation can be provided to or from the structure. An at least partially reflective arrangement can have multiple surfaces, where the reflecting arrangement can be situated with respect to the optical arrangement such that the surfaces thereof each can receive a(s) beam of the electromagnetic radiations instantaneously, and a receiving arrangement(s) which can be configured to receive the reflected radiation from the surfaces which include speckle patterns.

Abstract translation: 用于获得关于生物结构的信息的装置可以包括例如可以包括可以传播电磁辐射的光纤的导光装置，其中可以向结构或从结构提供电磁辐射 。 至少部分反射布置可以具有多个表面，其中反射布置可以相对于光学布置定位，使得其表面每个可以瞬间接收电磁辐射的波束，以及接收装置， 其可以被配置为从包括斑点图案的表面接收反射的辐射。

公开(公告)号：WO2013164468A1

公开(公告)日：2013-11-07

申请号：PCT/EP2013059295

申请日：2013-05-03

Applicant: FRAS TECHNOLOGY

Inventor： FJERDINGSTAD SOLVE

IPC: G01N21/05 ,  G01N1/20 ,  G01N15/02 ,  G01N21/47 ,  G01N21/53 ,  G01N21/85 ,  G01N33/28

CPC classification number: G01N21/49 ,  G01M3/06 ,  G01N1/2035 ,  G01N15/0227 ,  G01N21/05 ,  G01N21/474 ,  G01N21/532 ,  G01N21/85 ,  G01N21/8507 ,  G01N2001/2071 ,  G01N2021/4742 ,  G01N2021/8557 ,  G01N2201/06113 ,  G01N2201/0697 ,  G01N2201/08 ,  G01N2201/0826 ,  G01N2201/0833 ,  G01N2201/084

Abstract: The embodiments herein relate to a system (100) for analyzing a fluid (103). The system (100) comprises a light source (110) configured to emit light for transmission through a first optical transmission means (107a) to a measurement device (105). The measurement device (105) comprises at least a part of the fluid (103) and is configured to be illuminated by the emitted light. The system comprises a second optical transmission means (107b) configured to transmit shadowed or reflected light from the fluid (103) when the measurement device (105) is illuminated to an image capturing device. The image capturing device (113) is configured to capture an image of the fluid (103) in the measurement device (105) based on the transmitted information about the fluid (103). The light source (110) and the one or more image capturing device (113) are remotely arranged from the at least one measurement device (105).

Abstract translation: 本文的实施例涉及用于分析流体（103）的系统（100）。 系统（100）包括被配置为发射光以通过第一光传输装置（107a）传输到测量装置（105）的光源（110）。 测量装置（105）包括流体（103）的至少一部分并被构造成被发射的光照亮。 该系统包括第二光传输装置（107b），其被配置为当测量装置（105）被照射到图像捕获装置时，从流体（103）传输阴影或反射的光。 图像捕获装置（113）被配置为基于所传送的关于流体的信息（103）来捕获测量装置（105）中的流体（103）的图像。 所述光源（110）和所述一个或多个图像捕获装置（113）从所述至少一个测量装置（105）远程布置。

公开(公告)号：WO2013131017A1

公开(公告)日：2013-09-06

申请号：PCT/US2013/028693

申请日：2013-03-01

Applicant: LAXCO, INC.

Inventor： CHEN, Cong, Liang ,  CASSADY, Kevin

IPC: G01N37/00 ,  G01N21/00

CPC classification number: G01N21/0303 ,  G01N21/01 ,  G01N21/17 ,  G01N21/253 ,  G01N21/27 ,  G01N21/6452 ,  G01N2201/0639 ,  G01N2201/08 ,  G01N2201/0826 ,  G02B6/006 ,  G02B6/04 ,  G02B6/29388 ,  G02B6/32

Abstract: An analytical instrument may have multiple distinct channels. Such may include one or more illumination sources and sensors. Illumination may be delivered to specific locations of a specimen holder, and returned illumination may be delivered to specific locations of a sensor array. Illumination may first pass a specimen, and a mirror or reflector may then return the illumination past the specimen. Optical splitters may be employed to couple pairs of fiber optics proximate a specimen holder. Such channels may further include a plurality of illumination sources positioned on one side of a specimen holder and a plurality of sensors on the other side. The plurality of sensor may capture image of a specimen and a spectrophotometer may concurrently scan the specimen. A plurality of specimens may be imaged and scanned in a single pass of a plurality of passes. Spherical or ball lenses may be placed in an optical path of the illumination to achieve a desired illumination pattern.

Abstract translation: 分析仪器可能具有多个不同的通道。 这样可以包括一个或多个照明源和传感器。 照明可以被传送到样本保持器的特定位置，并且返回的照明可以被传送到传感器阵列的特定位置。 照明可以首先通过样本，然后镜子或反射器可以使照射通过样本。 可以使用光分路器将靠近样本保持器的成对的光纤耦合。 这样的通道还可以包括位于样品架一侧的多个照明源和另一侧的多个传感器。 多个传感器可以捕获样本的图像，并且分光光度计可以同时扫描样本。 可以在多次通过的单次通过中对多个样本进行成像和扫描。 球形或球形透镜可以放置在照明的光路中以实现期望的照明图案。

公开(公告)号：WO2010007617A2

公开(公告)日：2010-01-21

申请号：PCT/IL2009000684

申请日：2009-07-09

Applicant: BRIGHTVIEW SYSTEMS LTD ,  FINAROV MOSHE

Inventor： FINAROV MOSHE

IPC: G01N21/95 ,  G01N21/31

CPC classification number: G01N21/8422 ,  G01N21/31 ,  G01N21/6489 ,  G01N21/8901 ,  G01N2021/3568 ,  G01N2021/8908 ,  G01N2201/0826 ,  G01N2201/0833 ,  G01N2201/1085

Abstract: Photovoltaic thin film quality control is obtained where the thin film is supported by a support and a section of the film is illuminated by a polychromatic illumination source. The source forms on the thin film a continuous illuminated line. Discrete sampled points located on the illuminated line are imaged onto a two dimensional optical switch. A concordance look-up-table between the coordinates of the above sampled points on the thin film and their coordinates on the two dimensional optical switch are generated. The spectral composition of the illumination reflected by the sampled points is determined and photovoltaic thin film parameters applicable to the quality control are derived from the spectral composition of reflected or transmitted by the photovoltaic thin film illumination.

Abstract translation: 获得光电薄膜质量控制，其中薄膜由支撑体支撑并且膜的一部分被多色照明源照射。 源在薄膜上形成连续的照明线。 位于照明线上的离散采样点成像到二维光学开关上。 产生薄膜上面的采样点的坐标与二维光开关上的坐标之间的一致性查找表。 确定由采样点反射的照明的光谱组成，并且适用于质量控制的光电薄膜参数是从光电薄膜照射反射或透射的光谱组成得出的。

公开(公告)号：WO2009050633A1

公开(公告)日：2009-04-23

申请号：PCT/IB2008/054197

申请日：2008-10-13

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH ,  KOEHLER, Thomas ,  NIELSEN, Tim ,  BRENDEL, Bernhard, J. ,  ZIEGLER, Andy ,  ZIEGLER, Ronny ,  BAKKER, Levinus, P. ,  VAN DER MARK, Martinus, B.

Inventor： KOEHLER, Thomas ,  NIELSEN, Tim ,  BRENDEL, Bernhard, J. ,  ZIEGLER, Andy ,  ZIEGLER, Ronny ,  BAKKER, Levinus, P. ,  VAN DER MARK, Martinus, B.

IPC: A61B5/00 ,  G01N21/47

CPC classification number: G01N21/4795 ,  A61B5/0073 ,  A61B5/0091 ,  A61B5/4312 ,  A61B2562/146 ,  G01N2021/1787 ,  G01N2201/0826 ,  G01N2201/0833

Abstract: A device (1) for imaging the interior of an optically turbid medium is provided. The device comprises a receptacle (3; 103) structured to accommodate an optically turbid medium for examination and an optically matching medium filling a space between an inner surface (6; 106) of the receptacle (3; 103) and the optically turbid medium. The device comprises at least one light source generating light to be coupled into the receptacle (3; 103) and at least one detector for detecting light emanating from the receptacle (3; 103). A coupling surface (10; 110) optically coupled to the inner surface (6; 106) of the receptacle and a coupling member (11; 111) optically coupled to the light source and the detector are provided. The coupling surface (10; 110) and the coupling member (11; 111) are movable to a plurality of different positions relative to each other and structured to establish an optical connection from the light source to the inner surface (6; 106) of the receptacle and from the inner surface (6; 106) of the receptacle to the at least one detector in the plurality of different positions.

Abstract translation: 提供了用于对光学混浊介质的内部成像的装置（1）。 该装置包括构造成容纳用于检查的光学混浊介质的容器（3; 103）和填充容器（3; 103）的内表面（6; 106）与光学混浊介质之间的空间的光学匹配介质。 所述装置包括至少一个光源，其产生要耦合到所述插座（3; 103）中的光和至少一个用于检测从所述插座（3; 103）发出的光的检测器。 光耦合到容器的内表面（6; 106）的耦合表面（10; 110）和光学耦合到光源和检测器的耦合构件（11; 111）。 联接表面（10; 110）和联接构件（11; 111）可以相对于彼此移动到多个不同的位置，并被构造成建立从光源到内表面（6; 106）的光学连接 所述容器和所述容器的内表面（6; 106）到所述多个不同位置中的所述至少一个检测器。

公开(公告)号：WO2007131055A3

公开(公告)日：2008-12-04

申请号：PCT/US2007068061

申请日：2007-05-02

Applicant: OCELA TECHNOLOGIES

Inventor： HEANUE JOHN F ,  HEANUE JOSEPH A ,  WILFLEY BRIAN P ,  LOWELL AUGUSTUS P

IPC: G01N21/76

CPC classification number: G01N21/6408 ,  A61B5/0071 ,  A61B5/0084 ,  A61B5/415 ,  A61B5/418 ,  A61B5/6848 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/10 ,  G01J3/2823 ,  G01J3/4406 ,  G01N2201/0826 ,  G01N2201/0833

Abstract: A system and method for measuring fluorescence lifetimes utilizing a light source modulated with a code sequence to interrogate a sample of interest. The system is useful for studying the interaction of chemicals, biomolecules, and other substances. The fluorescence lifetime is used as an indicator of chemical binding and chemical environment. A system and method for measuring photons. The system produces an estimate of the distribution of flight times for photons traveling from the source to the detector. A system and method for optical lymph node mapping. A correlation of a photo-detector signal and a digital code sequence, used to modulated light signal, is calculated to produce an estimate of the distribution of flight times for photons traveling from a given source to a given detector. These distributions are used along with the measured amplitudes to reconstruct a map of contrast agent location within the tissue.

Abstract translation: 一种利用利用代码序列调制的光源来测量荧光寿命的系统和方法来询问感兴趣的样品。 该系统可用于研究化学物质，生物分子和其他物质的相互作用。 荧光寿命用作化学结合和化学环境的指标。 用于测量光子的系统和方法。 该系统产生从源到检测器的光子的飞行时间分布的估计。 一种用于光学淋巴结图谱的系统和方法。 计算用于调制光信号的光检测器信号和数字码序列的相关性，以产生从给定源到给定检测器的光子的飞行时间分布的估计。 这些分布与测量的幅度一起使用以重建组织内造影剂位置的图。

公开(公告)号：WO2008041524A1

公开(公告)日：2008-04-10

申请号：PCT/JP2007/068433

申请日：2007-09-21

Applicant: 富士フイルム株式会社 ,  小倉 信彦

Inventor： 小倉 信彦

IPC: G01N21/27

CPC classification number: G01N21/253 ,  G01N2201/0826 ,  G01N2201/0833

Abstract: 【課題】バイオセンサ検出装置において、装置構成の複雑化および装置サイズの大型化を抑制しつつ測定における処理能力を高める。 【解決手段】複数の領域に区画されたバイオセンサ（１０）中の各測定領域（Ｒ）の全てで反射された光束（Ｌｒ）それぞれを同時に分光可能な１つ以上の分光器（２０）によって分光された各光束（Ｌｓ）の全てを、１つ以上の受光器（３０）で同時に受光して各光束（Ｌｓ）のスペクトル強度分布を個別に取得可能とする。

Abstract translation: [问题]为了提高生物传感器的测量性能而不使设备配置复杂并增加设备尺寸。 解决问题的方法光谱仪（20）可以将由所有测量区域（R）反射的光通量（Lr）同时分散在划分成多个区域的生物传感器（10）中。 通过一个或多个光接收器（30）同时接收由一个或多个光谱仪分散的所有光通量（Ls），并分别获得每个光通量（Ls）的光谱强度分布。

公开(公告)号：WO2008039988A2

公开(公告)日：2008-04-03

申请号：PCT/US2007/079906

申请日：2007-09-28

Applicant: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES ,  GODAVARTY, Anuradha ,  REGALADO, Steven ,  JAYACHANDRAN, Bhavani ,  ZHU, Banghe

Inventor： GODAVARTY, Anuradha ,  REGALADO, Steven ,  JAYACHANDRAN, Bhavani ,  ZHU, Banghe

IPC: A61B5/00 ,  G01N21/47 ,  G02B6/08 ,  G02B6/06

CPC classification number: G02B6/06 ,  A61B5/0091 ,  A61B5/064 ,  A61B5/4312 ,  G01N21/359 ,  G01N21/474 ,  G01N21/4795 ,  G01N21/6456 ,  G01N2021/1787 ,  G01N2021/4742 ,  G01N2201/0221 ,  G01N2201/0826 ,  G01N2201/0833 ,  G02B6/08

Abstract: The claimed method and system uses a hand-held based optical process to image large tissue volumes using a flexible probe head, increased data acquisition using multi-source illumination and multi-detector sensing, and tomographic reconstruction of sub-surface structures of a target object using ultrasonic tracking facilities.

Abstract translation: 所要求保护的方法和系统使用基于手持的光学过程来使用柔性探头来成像大的组织体积，使用多源照明和多检测器感测的增加的数据采集以及目标对象的子表面结构的断层重建 使用超声波跟踪设施。

公开(公告)号：WO2007016544A3

公开(公告)日：2007-09-27

申请号：PCT/US2006029884

申请日：2006-07-31

Applicant: OG TECHNOLOGIES INC ,  CHANG TZYY-SHUH ,  GUTCHESS DANIEL ,  HUANG HSUN-HAU

Inventor： CHANG TZYY-SHUH ,  GUTCHESS DANIEL ,  HUANG HSUN-HAU

IPC: G06K9/00 ,  G01B20060101 ,  G01B11/30 ,  G01N21/88 ,  G01N21/95 ,  G01N21/952 ,  H04N7/18 ,  H04N9/47

CPC classification number: G01N21/952 ,  G01N2201/0826 ,  G01N2201/084 ,  H04N7/18

Abstract: The present invention is directed to solving the problems associated with the detection of surface defects on metal bars as well as the problems associated with applying metal flat inspection systems to metal bars for non-destructive surface defects detection. A specially designed imaging system, which is comprised of a computing unit, line lights and high data rate line scan cameras, is developed for the aforementioned purpose. The target application is the metal bars (1) that have a circumference/cross-section-area ratio equal to or smaller than 4.25 when the cross section area is unity for the given shape, (2) whose cross-sections are round, oval, or in the shape of a polygon, and (3) are manufactured by mechanically cross-section reduction processes. The said metal can be steel, stainless steel, aluminum, copper, bronze, titanium, nickel, and so forth, and/or their alloys. The said metal bars can be at the temperature when they are being manufactured. A removable cassette includes various mirrors. A protection tube isolates the moving metal bar from the line light assembly and image acquisition camera. assembly and image acquisition camera. A contaminant reduction mechanism applies a vacuum to remove airborne contaminants.

Abstract translation: 本发明旨在解决与检测金属棒表面缺陷相关的问题以及将金属平面检查系统应用于金属棒以用于非破坏性表面缺陷检测相关的问题。 为了上述目的开发了一种专门设计的成像系统，由计算单元，线路灯和高数据速率线扫描摄像机组成。 目标应用是当给定形状的横截面积为1时，具有等于或小于4.25的圆周/横截面积比的金属棒（1），（2）横截面为圆形，椭圆形 ，或多边形的形状，（3）通过机械截面缩小工艺制造。 所述金属可以是钢，不锈钢，铝，铜，青铜，钛，镍等，和/或它们的合金。 所述金属棒可以处于制造时的温度。 可拆卸的盒子包括各种镜子。 保护管将移动的金属条与线灯组件和图像采集相机隔离。 装配和图像采集相机。 污染物减少机制应用真空去除空气污染物。

公开(公告)号：WO2004063698A2

公开(公告)日：2004-07-29

申请号：PCT/IL2004/000023

申请日：2004-01-11

Applicant: NEGEVTECH LTD. ,  FURMAN, Dov ,  NEUMANN, Gad ,  WAGNER, Mark ,  DOTAN, Noam ,  SEGAL, Ram ,  SILBERSTEIN, Shai

Inventor： FURMAN, Dov ,  NEUMANN, Gad ,  WAGNER, Mark ,  DOTAN, Noam ,  SEGAL, Ram ,  SILBERSTEIN, Shai

IPC: G01N

CPC classification number: G01N21/9501 ,  G01N21/8806 ,  G01N21/95607 ,  G01N21/95623 ,  G01N2021/479 ,  G01N2021/8825 ,  G01N2201/0697 ,  G01N2201/0826

Abstract: Fast on-line electro-optical detection of wafer defects by illuminating with a short light pulse from a repetitively pulsed laser, a section of the wafer while it is moved across the field of view of an imaging system, and imaging the moving wafer onto a focal plane assembly, optically forming a continuous surface of photo-detectors at the focal plane of the optical imaging system. The continuously moving wafer is illuminated by a laser pulse of duration significantly shorter than the pixel dwell time, such that there is effectively no image smear during the wafer motion. The laser pulse has sufficient energy and brightness to impart the necessary illumination to each sequentially inspected field of view required for creating an image of the inspected wafer die. A novel fiber optical illumination delivery system, which is effective in reducing the effects of source coherence is described. Other novel aspects of the system include a system for compensating for variations in the pulse energy of a Q-switched laser output, methods for autofocussing of the wafer imaging system, and novel methods for removal of repetitive features of the image by means of Fourier plane filtering, to enable easier detection of wafer defects.

Abstract translation: 通过用来自重复脉冲激光器的短光脉冲照射晶片缺陷的快速在线电光检测，晶片的一部分在成像系统的视场内移动，并将移动的晶片成像到 焦平面组件，在光学成像系统的焦平面处光学地形成光电检测器的连续表面。 持续移动的晶片被持续时间明显短于像素停留时间的激光脉冲照亮，使得在晶片运动期间实际上没有图像污迹。 激光脉冲具有足够的能量和亮度，以对于产生被检查的晶片管芯的图像所需的每个顺序检查的视场赋予必要的照明。 描述了一种有效减少源相干效应的新型光纤照明传输系统。 该系统的其他新颖的方面包括用于补偿Q开关激光输出的脉冲能量变化的系统，用于晶片成像系统的自动聚焦的方法，以及通过傅立叶平面去除图像的重复特征的新颖方法 过滤，以便更容易地检测晶片缺陷。