Abstract:
Peptides having at least nine amino acid residues each including an amino acid sequence which corresponds to position p200-208 or p262-266 of the human acetylcholine receptor α-subunit, but differing therefrom by one or more amino acid substitutions, are disclosed. These peptides inhibit the proliferative response of human peripheral blood lymphocytes to the myasthogenic peptides p195-212 and p259-271 and are suitable for treatment of subjects afflicted with myasthenia gravis.
Abstract:
A rechargeable zinc halide electrolyte electrochemical cell including a laminate of the sequence a) an electrically conducting chemically inert material, b) a bilayer membrane matrix formed from a pair of hydrophilic polymer matrices in each of which is immobilized zinc halide electrolyte, c) an electrically conducting layer adapted to adsorb and absorb halogen, and d) a layer capable of reversibly absorbing and releasing bromine disposed between the membrane matrices for reducing self-discharging in the cell.
Abstract:
A radiation convertor for use in neutron imaging detectors includes apparatus for conversion of energetic primary charged particles resulting from neutron capture into low energy (eV) secondary electrons. The radiation convertor includes efficient secondary electron emitters, which are preferably alkali halide secondary electron emitters which are preferably CsI secondary electron emitters. The radiation convertor preferably combines at least one layer of Gd and an efficient secondary electron emitter preferably of alkali halide, preferably CsI. The layer of Gd may be at least one metallic layer selected from natural Gd and 157 Gd and this is used in combination with a layer of CsI. The neutron convertor may be alternatively 6Li, LiH or 177 Hf used in combination with an efficient secondary electron emitter, preferably alkali halide emitter, preferably CsI. A neutron imaging detector of the invention may combine a secondary emission composite neutron convertor including efficient secondary electron emitters and an electron multiplier which is sensitive to low energy secondary electrons emitted from the composite neutron convertor. In such a neutron imaging detector combination, the electron multiplier may be a vacuum micro channel plate (MCP) multiplier, a vacuum microsphere plate (MSP), or any other vacuum electron multiplier and imaging device, or a gaseous electron imaging multiplier, preferably a gaseous electron multiplier in which the secondary electron multiplication starts at their emission location from the convertor, preferably a low-pressure multistage electron multiplier.
Abstract:
Conjugates of chlorophyll (Chl) and bacteriochlorophyll (Bchl) derivatives with amino acids, peptides and proteins are provided by the invention.The amino acid, peptide or protein residue is linked to the 17-propionic acid group of a Chl or Bchl residue directly or through a chain.The conjugates are for use as photosensitizers in photodynamic therapy and in diagnostics of tumors. Conjugation with cell-specific ligands, such as hormones, growth factors or tumor-specific antibodies, will target the Chl or Bchl moiety to the tumor site. Thus, conjugates with melanocyte stimulating hormones are suitable for photodynamic therapy of melanoma tumors.
Abstract:
Water softening is achieved by a combination of electrodialysis and calcium carbonate precipitation. The hard feed water or alternatively recycled soft water is rendered alkaline and is then subjected to a treatment by which precipitation of calcium carbonate is induced. One way of bringing about such precipitation consists in passing the alkaline water across a cake of calcium carbonate crystals having a size not exceeding 100 microns, deposited on a filter (43) and being in an at least fifty fold excess over the amount of calcium carbonate to be precipitated.
Abstract:
L'invention concerne des agents antiviraux, des préparations pharmaceutiques comprenant des quantités efficaces desdits agents, ainsi que des procédés de traitement de mammifères souffrant d'infections provoquées par des virus. Lesdits agents sont des analogues, des isomères, des homologues, des dérivés et des sels de diones polycycliques aromatiques.
Abstract:
A purified protein derived from Leishmania donovani , for use as antigen in an assay for the determination of Leishmaniasis and for use in vaccines against this disease. Such proteins react with monoclonal antibodies raised against Leishmania donovani . Identical or equivalent proteins can be produced by recombinant DNA technology. Instead of the proteins there can also be used effective segments thereof.
Abstract:
An electron multiplier including a multi-layer arrangement of material which provides secondary electron emissions when impinged upon by electrons and apparatus for applying an electric field across the material. A cathode ray tube, and devices incorporating a cathode ray tube, such as televisions and oscilloscopes are also provided in accordance with the invention.